Last updated on December 24, 2021

Content By: Dr. Nikita Toshi BDS, Assistant Manager (Medical Review) & Dr. Ritu Budania MBBS, MD (Pharmacology) Head, Medical Affairs

Last updated on December 24, 2021

Overview


Diabetes, a term that we’re pretty familiar with. From friendly gatherings to family functions, diabetes is often a matter of conversation and contention. What to eat? What not to eat? What works and what doesn’t? Everyone seems to have an opinion and the conversation seems endless.

As we may know, there are two types of diabetes that are commonly known – Type 1 and Type 2 diabetes. As a population, we need to understand what Type 1 and Type 2 diabetes are. But before we delve deep, let’s cover the basics.

Diabetes occurs:

  • when the pancreas stops producing insulin.
  • when the pancreas generates only a tiny amount of insulin.

Insulin resistance is a condition that occurs when the body does not appropriately use the insulin it produces.

The difference between Type 1 and Type 2 diabetes is that people who have Type 1 diabetes don’t produce insulin. It is the equivalent of not having a key to a lock. People with Type 2 diabetes, on the other hand, don’t respond to insulin as well as they should and they typically don’t produce enough insulin as the disease progresses. It’s equivalent to having a misshapen key to a lock.

While Type 1 diabetes is a condition usually diagnosed in children and young adults, Type 2 diabetes mellitus usually occurs in adult life (though it can occur in children as well).

Without further ado, let’s look at what Type 2 diabetes is and how prevalent it’s in the Indian subcontinent.


Overview


Diabetes, a term that we’re pretty familiar with. From friendly gatherings to family functions, diabetes is often a matter of conversation and contention. What to eat? What not to eat? What works and what doesn’t? Everyone seems to have an opinion and the conversation seems endless.

As we may know, there are two types of diabetes that are commonly known – Type 1 and Type 2 diabetes. As a population, we need to understand what Type 1 and Type 2 diabetes are. But before we delve deep, let’s cover the basics.

Diabetes occurs:

  • when the pancreas stops producing insulin.
  • when the pancreas generates only a tiny amount of insulin.

Insulin resistance is a condition that occurs when the body does not appropriately use the insulin it produces.

The difference between Type 1 and Type 2 diabetes is that people who have Type 1 diabetes don’t produce insulin. It is the equivalent of not having a key to a lock. People with Type 2 diabetes, on the other hand, don’t respond to insulin as well as they should and they typically don’t produce enough insulin as the disease progresses. It’s equivalent to having a misshapen key to a lock.

While Type 1 diabetes is a condition usually diagnosed in children and young adults, Type 2 diabetes mellitus usually occurs in adult life (though it can occur in children as well).

Without further ado, let’s look at what Type 2 diabetes is and how prevalent it’s in the Indian subcontinent.


Written by:

Dr. Nikita Toshi

BDS, Assistant Manager (Medical Review)

Reviewed by:

Dr. Ritu Budania

MBBS, MD (Pharmacology) Head, Medical Affairs

Type 2 diabetes is a lifestyle illness that leads to high levels of blood sugar in your body. This kind of diabetes is more common in middle-aged people. It was previously known as adult-onset diabetes. However, now Type 2 diabetes mellitus is affecting children and teenagers, owing to childhood obesity.

In this case, your body’s cells can’t respond to insulin as well as they should. And as the disease progresses, your body may not generate enough insulin. Uncontrolled Type 2 diabetes could result in chronically high blood glucose levels, which can cause a variety of symptoms and consequences.

Diabetes is a significant issue in India, with an estimated 8.7% diabetic population between 20 and 70. Rapid urbanization, sedentary lifestyles, bad diets and cigarette use contribute to the increased incidence of diabetes.

What is type 2 diabetes? Using a glucometer to measure the blood sugar levels

Now that we have got an understanding of what type 2 diabetes is, in this section, we’ll cover what symptoms you need to be concerned about regarding the same.

In the case of Type 2 diabetes mellitus, your body can’t efficiently use insulin to carry glucose into your cells. As a result, your tissues, muscles and organs must depend on different energy sources. This search for various energy sources could cause a range of Type 2 diabetes symptoms.

It may take a long time for symptoms of Type 2 diabetes to develop. At first, the symptoms may appear to be minor and straightforward to dismiss. Some early signs of Type 2 diabetes may include:

  Increase in thirst

  Blurred vision

  Peeing frequently

  Constant irritability

  Numbness or tingling in your hands or feet

  Fatigue or a feeling of exhaustion

  Yeast infections that happen frequently

  Feeling hungry all the time

  Unexplained weight loss

  Developing new infections

What is type 2 diabetes? Understanding symptoms of type 2 diabetes

If the condition is left undiagnosed and untreated, symptoms could waterfall into complications. If your blood sugars have been elevated for an extended period, you may have the following symptoms:

  • Wounds or sores that don’t heal easily.
  • Acanthosis nigricans – a disorder that causes dark velvety spots on your skin especially around elbows, neck and armpits.
  • Neuropathy, characterized by numbness in the extremities.
  • Diabetic foot – soreness and wounds in feet.
  • Disturbed vision and pain in the eyes.

If you experience any of these signs and symptoms of Type 2 diabetes, you should consult a doctor immediately as it could cause serious repercussions if left untreated.

In a Nutshell
    • Type 2 diabetes mellitus is a chronic condition that prevents your body from using insulin properly.
    • Type 2 diabetes symptoms include – unusual thirst, blurry vision, frequent urination, fatigue, unusual hunger, irritability, numbness in limbs, frequent yeast infections and unusual weight loss.
    • While type 2 diabetes is common in the middle-aged population, children, young adults and teenagers are not exempt from developing the condition. Therefore, early detection goes a long way in effectively managing the condition.

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What is insulin and how does it help my body regulate blood sugar?

Insulin is a hormone produced by your pancreas. Insulin aids in the transport of glucose from your bloodstream to the body’s cells, where it’s utilized for the generation of energy. Type 2 diabetics produce insulin but unfortunately, their cells don’t use it as well as they should.

Initially, to get the glucose into your cells, your pancreas tries to produce more insulin. Eventually, it becomes tired and is unable to keep up. As a result, glucose levels build up in your blood and your body’s cells don’t get the energy they require.

Main Causes of Type 2 Diabetes

The two main causes for type 2 diabetes mellitus are:

Insulin resistance – The cells in the body, especially those in the muscle, fat cells and cells in the liver, become resistant to insulin and do not respond to insulin as they used to normally. This causes the level of sugar to build up in the blood. Insulin resistance is frequently associated with a slew of symptoms, including high blood sugar, belly fat, high blood pressure, as well as high cholesterol and triglycerides.

Cell dysfunction in the pancreas – Over a period of time, the beta cells of the pancreas which produce insulin are unable to produce enough insulin to meet the demands of rising blood sugar levels.

Now that we’ve covered what Type 2 diabetes is, along with its signs and symptoms and causes, let’s look at the risk factors that could lead to Type 2 diabetes mellitus.

Risk factors of Type 2 Diabetes - What can possibly lead to it?

Researchers aren’t yet sure why some people get prediabetes and Type 2 diabetes while others don’t. What we do know about Type 2 diabetes is that certain circumstances clearly heighten the risk. They include:

Bodyweight and inactivity – The fattier tissue you have in your body, the higher is the risk for your cells to become resistant to insulin. And the lower your level of activity and movement, the higher your chances of getting Type 2 diabetes mellitus. Physical exercise aids in weight management by using glucose as an energy source.

Family history – If your parent or sibling has Type 2 diabetes mellitus, you’re more likely to develop the condition in the future.

Age – As you get older, your chance of developing Type 2 diabetes rises, especially after the age of 45.

High cholesterol levels, and a history of heart disease and blood pressure

Prediabetes – In it, the blood sugar level is greater than usual but not high enough to be classed as diabetes. Prediabetes frequently evolves into Type 2 diabetes if left untreated.

Risks associated with pregnancy – If you had gestational diabetes while pregnant or gave birth to a kid weighing more than 9 pounds (4 kilograms), you’re more likely to develop Type 2 diabetes in the future.

Polycystic ovarian syndrome – Polycystic ovarian syndrome, a common condition that arises due to hormonal imbalance marked by irregular menstrual cycles, excessive hair growth and obesity, raises the chance of a diagnosis of Type 2 diabetes in females.

Smoking and Alcohol – Excessive smoking and alcohol intake can also act as risk factors for type 2 diabetes.

Stress – Stress might also increase your risk of getting Type 2 diabetes. Your body’s stress hormones may have a direct impact on your glucose levels.

Steroid-induced medications – Some medicines (eg. corticosteroids and some medicines for mental illness) when taken for a long term may increase your risk of developing type 2 diabetes mellitus.

What is type 2 diabetes? Knowing the risk factors of type 2 diabetes

In a Nutshell
    • Insulin is a hormone secreted by the pancreas that plays an important role in regulating blood glucose levels in the body. It helps transport the glucose absorbed through food from the blood into the cells where it is then metabolized for energy.
    • Some causes of type 2 diabetes include – insulin resistance, cell dysfunction in the pancreas, etc.
    • You may be at risk of developing type 2 diabetes in the future if you lead a sedentary lifestyle without physical activity, if you are overweight, if you are older than 45, if you have been diagnosed with prediabetes, if your family has a history of diabetes or gestational diabetes, if you’re dealing with stress or have been diagnosed with PCOS.

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Do you want to know what you can do to diagnose Type 2 diabetes? If so, you’ve come to the right place.

Your doctor usually tests your blood for indicators of Type 2 diabetes. They’ll usually test you again in two days to confirm the diagnosis. However, if your blood glucose is high or you have several symptoms, one test may be sufficient. Here are a few diagnostic tests, you or your loved one can be prepared for:

1. HbA1C (Haemoglobin A1C test for diabetes)

This test is known as the glycated haemoglobin test and is similar to taking an average of your blood glucose levels over the previous two or three months.

Result Interpretation
< 5.7% Normal
5.7% to 6.4% Prediabetes
6.5% or higher Diabetes

2. Fasting Blood Sugar Test For Diabetes

A fasting blood sugar test is taken on an empty stomach. For the 8 hours leading up to the test, you won’t be permitted to eat or drink anything but water.

This is how your doctor will interpret the results:

  • It’s normal to have a blood sugar level of less than 100 mg/dL.
  • Prediabetes is defined as a blood sugar level that lies between 100 to 125 mg/dL.
  • Diabetes is diagnosed when blood sugar levels are at or higher than 126 mg/dL or greater on two different tests.
Result Interpretation
< 100 mg/dL Normal
100 to 125 mg/dL Prediabetes
126 mg/dL or higher Diabetes

3. Oral Glucose Tolerance Test (OGTT)

For this test, you’ll need to fast overnight before going to the doctor’s office and over there, after checking your fasting blood sugar, you’ll be asked to drink a sweet beverage. For the following two hours, blood sugar levels are checked at periodic intervals. This test helps to know how your body processes sugar. Here is how the results are interpreted after 2 hours:

  • A blood sugar level of less than 140 mg/dL is considered normal.
  • A blood sugar level between 140 to 199 mg/dL is considered prediabetic.
  • After two hours, a blood sugar level of 200 mg/dL or greater indicates diabetes.
Result Interpretation
< 140 mg/dL Normal
140 mg/dl to 199 mg/dL Prediabetes
200 mg/dL or higher after two hours Diabetes

4. Post Prandial Blood Sugar Test (PPBS)

Blood sugar is tested 2 hours after the patient has taken one full meal. This test helps to give an idea of the peak rise in blood sugar level that may happen after consuming food. It also depends on the type and quantity of meal the patient has consumed on the day of the test. Hence, it may also give an inappropriate result as most patients tend to consume an unusually low carb diet on the day of the test. Results of both FBS and PPBS are considered for interpretation:

Stage of Diabetes Fasting Post-Prandial
Diabetes 126 mg/dL or above 200 mg/dL or above
Pre-diabetes 100-125 mg/dL 140-199 mg/dL
The normal blood glucose level below 100 mg/dL Below 140 mg/dL

5. Random Blood Sugar Test (RBS)

RBS is the blood sugar test that is done at any time of the day irrespective of the time lapsed after meals. This gives an overview of the blood sugar levels and is usually advised by your doctor during other lab tests or before any surgical procedure to rule out a risk of undiagnosed diabetes.

A random blood sugar level below 200 is considered normal. Anything above 200 is suggestive of diabetes mellitus.

Am I at risk? Who needs to be screened for Type 2 Diabetes?

The American Diabetes Association advises routine Type 2 diabetes screening test using diagnostic testing in all individuals 45 and older, as well as in the following groups:

People under the age of 45 who are overweight or obese and have one or more diabetes risk factors.

Women who have experienced gestational diabetes.

People with prediabetes.

Overweight or obese children with a family history of Type 2 diabetes or other risk factors.

In a Nutshell
    • Two main tests that doctors conduct to diagnose type 2 diabetes are the fasting blood sugar test and the HbA1c test.
    • An oral glucose tolerance test is primarily done to diagnose gestational diabetes in pregnant women.
    • A random blood sugar level below 200 is considered normal. Anything above 200 is suggestive of diabetes mellitus.

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Type 2 diabetes, although a chronic condition, can be effectively managed with a combination of lifestyle modifications and medication. By making lifestyle modifications through diet and exercise for diabetes, you might be able to manage your Type 2 diabetes mellitus. These include:

#1 Taking Medication for Diabetes

It is important to take the medicines prescribed by your doctor on time and follow up with your doctor regularly.

In patients with high blood pressure and high cholesterol, Blood pressure and cholesterol-lowering medicines may also be prescribed by your doctor in addition to diabetic medications to help prevent heart and blood vessel damage as a result of uncontrolled sugar levels.

#2 Following a healthy diet for diabetes

Contrary to common belief, there is no such thing as one specific diabetic diet for all. However, it’s critical to focus your diet on:

Lowering your calorie intake.

Reducing refined carbohydrates, particularly sweets and processed foods.

Adding fruits and vegetables to your diet.

Increasing your fibre intake.

Eating in small portions at frequent intervals.

Your doctor may suggest that you consult a certified dietician who can assist you with:

Determining which of your dietary preferences is healthy.

Planning nutritious and well-balanced meals.

Developing new habits and overcoming obstacles to change habits.

Keeping your blood sugar levels more steady.

#3 Physical activity

Exercising is crucial for weight loss and maintaining a healthy weight. It also aids in the control of Type 2 diabetes blood sugar levels. Before beginning or altering your exercise routine, consult your doctor to confirm that the activities are safe for you.

So, what are the best exercises for Type 2 diabetes patients?

Aerobic exercises – Pick an aerobic activity you love, such as walking, swimming, bicycling or running. Adults should strive for at least 150 minutes of moderate aerobic activity each week or 30 minutes on most days of the week. Every day, children should engage in 60 minutes of moderate to intense aerobic activity.

Resistance exercises – Resistance training improves your strength, balance and ability to carry out daily tasks more easily. Weightlifting, yoga for diabetes and calisthenics are all examples of resistance training.

#4 Weight Management

Weight loss that basically aims at shedding off that extra fat, leads to better regulation of your blood sugar, cholesterol, triglyceride and blood pressure. If you’re overweight, you could see a difference in these factors with just a 5% loss of your body weight. The more weight you lose, the better you’ll be able to manage Type 2 diabetes mellitus.

Your doctor or dietician can help you create realistic weight-loss goals and urge you to make lifestyle changes to help you reach them.

#5 Regularly monitoring your blood sugar levels

Your doctor will tell you how often you should check your blood sugar to make sure you stay within your goal range.

A blood glucose meter, a tiny at-home device that detects the quantity of sugar in a drop of your blood, is often used for monitoring. It is best to keep note of the information so you can show them to your doctor upon visit.

#6 Insulin therapy

Insulin therapy may be required for certain patients with Type 2 diabetes mellitus. Insulin therapy was once considered a last resort, but it’s now more likely to be recommended if blood sugar goals aren’t attained with lifestyle modifications and other medications.

Though there are all these treatments of Type 2 diabetes mellitus, it takes a lot of effort to manage Type 2 diabetes. While your doctor may advise you to make dietary and exercise modifications, as well as adjustments to your general lifestyle, you don’t have to do it all by yourself. Having the support of friends, family and loved ones may help you remain on top of your illness and improve your mood. However, it’s equally important to seek out support from those who have diabetes. Others who have Type 2 diabetes mellitus know exactly what you’re going through. Currently, online support groups are a popular source of help.

In a Nutshell
    • Dietary alterations to include foods less in refined carbohydrates and more in protein and fibre has been seen to help diabetics effectively manage their blood sugar levels.
    • Physical activity, weight management along with other lifestyle alterations have seen to not only aid in weight loss and shedding of body fat but help people easily manage type 2 diabetes as a result.
    • Insulin therapy and diabetes medication may be recommended by your doctor in addition to diet, exercise and lifestyle alterations, to achieve a reduction in blood sugar levels.

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What you should know is that Type 2 diabetes isn’t always preventable. You generally can’t control your genetics, ethnicity or age.

However, irrespective of whether you have diabetes risk factors like prediabetes, a few lifestyle changes can help postpone or minimize the onset of Type 2 diabetes.

Being Active

Inactivity is related to the onset of Type 2 diabetes. Getting 30 minutes of aerobic activity each day can help you live a healthier life. Also, make an effort to move more during the day. Long periods of inactivity, such as sitting at a computer, can be broken up to help regulate blood sugar levels. Every 30 minutes, take a few minutes to stand, move about or perform some moderate movement.

Controlling your weight

If you’re overweight, you’re more likely to develop Type 2 diabetes. Keeping your weight under control may be as simple as eating a healthy, balanced meal and exercising on a daily basis. If such adjustments don’t work, your doctor can offer some weight-loss recommendations that are both safe and effective.

Getting a diabetes test regularly

If you have a predisposition to develop Type 2 diabetes mellitus, ensure that you take regular blood tests and stay ahead. Be aware of prediabetes symptoms so that you can prevent them before it becomes potentially dangerous.

Limiting your alcohol intake and smoking habits

Excessive alcohol intake and smoking can put you at a risk of developing diabetes. Quit or atleast try to limit these habits for good health.

Taking care of your mental and emotional health

Stress management techniques, meditation and relaxation exercises can be of great help in reducing the harmful effects of stress on your body.

Type 2 diabetes, though a chronic condition, can be effectively dealt with in many ways. Many type 2 diabetics have the potential to lead a normal life just like any other and hence do not have to fear the diagnosis itself. As mentioned above, dietary changes, physical activity and weight loss and other lifestyle modifications are some of the many ways you can keep your blood glucose levels in the optimal range throughout the day and help you effectively manage Type 2 diabetes.

In a Nutshell
    • Type 2 diabetes may not always be preventable as some factors like genetics, ethnicity and age are out of one’s control.
    • If diagnosed with prediabetes, a few ways that can help you prevent or delay the onset of type 2 diabetes in the future are by – being active and incorporating physical activity in your day-to-day life, being mindful of what you eat and ensure your diet is low in refined carbohydrates and sugars and lastly, regularly monitoring your blood sugar levels either by scheduling regular checkups with your doctor or by using a glucometer kit at home.

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What does diabetes Type 2 mean?

Type 2 diabetes is defined as a condition in which cells of your body are unable to properly utilize blood sugar (glucose) for producing energy. When cells become unresponsive to insulin, then blood sugar levels rise to harmful levels.

Can Type 2 diabetes be cured?

Though Type 2 diabetes has no recognized cure, it can be managed with the right treatment and lifestyle modifications.

Which is worse, Type 1 or 2 diabetes?

Type 1 diabetes treatment involves injecting insulin daily through injections, pen or pump which is not a very comfortable experience, however, most cases of type 2 diabetes respond well to oral medications and only some of them require insulin. Neither condition is life-threatening if managed appropriately and it is also true that both type 1 diabetes and type 2 diabetes may lead to serious complications if left untreated. So, you’ll need to ensure that you keep your blood sugar levels in check.

How long can you live with Type 2 diabetes?

The predicted life expectancy of a person varies greatly based on their age, lifestyle conditions and treatments.

For instance:

  • A 55-year-old man with Type 2 diabetes may expect to live another 13.2 – 21.1 years, with a general life expectancy of 24.7 years.
  • A 75-year-old man with the illness may expect to live for another 4.3 – 9.6 years, compared to a 10-year average life expectancy.

But don’t worry, a lot of people with Type 2 diabetes go on to live long and happy lives.

Who is most at risk for Type 2 diabetes?

Although we don’t know the specific causes of Type 2 diabetes, we know that some variables might increase the risk factor.

  • If you have a Type 2 diabetic sibling or parent, your risk is higher.
  • Type 2 diabetes can strike at any age, although the risk rises as you become older. Once you reach the age of 45 your risk increases.
  • African-Americans, Asian-Americans, Hispanic-Americans, Pacific Islanders and Native Americans (American Indians and Alaska Natives) are more vulnerable than Caucasians.
  • Women who suffer from polycystic ovarian syndrome (PCOS) are at a higher risk.
  • If you are obese and have a sedentary lifestyle.
  • If you have a habit of smoking and/or consuming alcohol excessively.

How do you reverse Type 2 diabetes?

Although there is no cure for Type 2 diabetes, you may be able to achieve and maintain normal blood sugar levels with the help of medication and by making dietary adjustments and losing weight.

Can Type 2 diabetes turn into Type 1?

Type 2 diabetes can not progress to Type 1 as both have different causes. However, a person who is first misdiagnosed with Type 2 diabetes may later be diagnosed with Type 1 diabetes. Because Type 2 diabetes mellitus is the most common, a doctor may think an adult with diabetes has it at first.

Can you be misdiagnosed with Type 2 diabetes?

A person with Type 2 diabetes likely gets misdiagnosed. Many of the symptoms of Type 2 diabetes may be present, but they may be suffering from a disease that’s more closely connected to Type 1 diabetes. In adults, this condition is known as latent autoimmune diabetes (LADA).

What is latent autoimmune diabetes in adults (LADA)?

Adults with latent autoimmune diabetes (LADA) have a kind of autoimmune diabetes that progresses slowly. LADA, like Type 1 diabetes, develops when your pancreas stops generating enough insulin, most likely as a result of some “injury” that destroys the pancreas insulin-making cells over time.

What is the difference between Type 2 diabetes and LADA?

LADA is identified in adulthood and develops slowly, similar to Type 2 diabetes. However, unlike type 2 diabetes, LADA is an autoimmune illness that affects your pancreas.

I don't eat sugar, nor do I eat rice; still I got Type 2 diabetes mellitus. Is that normal?

While we don’t know what causes Type 2 diabetes, it isn’t connected to a particular diet. Sugar or rice are not the cause of Type 2 diabetes. The rise in your sugar levels happens because the cells of your body do not respond to insulin the way they should to utilise the blood sugar. When this problem happens in metabolism, it does not matter whether the sugar in the blood has come from rice or any other dietary carbohydrate. Therefore, sugar or carbs aren’t a direct cause.

Will taking insulin make you gain weight?

Insulin therapy, a popular diabetic treatment, can lead to weight gain. However, insulin users can control their weight with specific dietary and lifestyle changes.

Doctor's Section

Dr. Nikita Toshi
Dr. Nikita works with PharmEasy as a medical content writer. She completed her B.D.S. from Rama Dental College, Hospital and Research Center, Kanpur in 2013 with an excellent academic record. Holding a clinical experience of 7 years in dental practice, she has worked at Rameti Oral and Maxillofacial Centre, Allahabad as Associate Dental Surgeon and Raipur Institute of Medical Sciences as Junior Resident. Her clinical skills include bleaching, restorations, R.C.T, Re R.C.T., single visit R.C.T. and F.P.Ds, dental extractions, minor OT procedures, oral prophylaxis, curettage, root planing, and perio-splint. Dr. Nikita frequently speaks on dental health talks organized at schools and other institutes to help in raising awareness on dental health in society. She has also written a research paper published in a reputed journal.

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Dr. Ritu Budania
Dr. Ritu Budania heads PharmEasy’s medical content and catalogue management teams. She did her MBBS from Topiwala National Medical College, Mumbai; followed by post-graduation in MD Pharmacology from Government Medical College, Nagpur. She was awarded a bronze medal for topping the Maharashtra University of Health Sciences in her MD. She has six publications in international and national medical journals. She is also an esteemed industry speaker in the field of pharmacology and has been invited as chief guest/speaker in several medical / pharmacy colleges. She has also helped author the World Health Organisation’s document on ‘Desk View and Situation analysis of Clinical Trials in India’ and helped in signal detection activities for the Pharmacovigilance Programme of India. She holds expertise in medical writing, ethics, and GCP in biomedical research, advanced pharmacovigilance, and biostatistics.

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