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Nasal Drops for Babies and Kids: Types, Uses, and Safety Guide 

Introduction

The nasal airway plays a vital role in both breathing and smell. In addition to allowing respiration, the nose and sinuses (air-filled spaces around the nose) help condition inhaled air by humidifying and filtering it, while also trapping harmful particles1.

This natural defence system is especially important in newborns, who rely mainly on nasal breathing during their first few months of life. Any obstruction of the nasal passages at this stage can therefore lead to significant issues, including breathing difficulty, sleep disturbances, feeding problems, and a higher risk of conditions such as obstructive apnoea1.

In infants and children, nasal obstruction and a runny nose are most commonly caused by viral upper respiratory tract infections (URTIs), allergic reactions, or neonatal rhinitis. Since babies cannot blow their noses effectively, the accumulation of mucus can worsen discomfort and respiratory distress1,2.

To relieve this, nasal drops or sprays are commonly recommended1,2.They are safe, gentle, and effective in easing congestion, but their correct and careful use is essential. Therefore, through this guide, we aim to help parents understand the different types of nasal drops available for babies, their uses, and important safety tips. 

What Are Nasal Drops and Sprays?

Nasal drops or sprays are liquid formulations designed to be placed directly into the nasal cavity to help relieve a blocked or stuffy nose. They are usually water-based (aqueous) solutions or suspensions and may contain active ingredients or simple saline1,3.

Nasal Drops vs. Nasal Sprays 

Both nasal drops and sprays are used to relieve nasal congestion, dryness, or allergies but the difference lies in how they are delivered3:

Saline nasal drops in particular are gentle, drug-free, and safe, making them a preferred choice for babies. They help loosen mucus, clear nasal passages, and improve breathing, which supports more comfortable feeding and sleeping1,2.

Types of Nasal Drops for Babies and Kids

Nasal drops or sprays are packaged in single-use or multi-use containers. They are often equipped with droppers or nozzles to ensure safe and accurate dosing3.

Nasal drops for kids can be either simple saline or medicated formulations, depending on the purpose: 

Saline Nasal Drops 

Medicated Nasal Drops (doctor-prescribed only) 

Another option is nasal sprays; however, these are generally used in older children. 

Saline Nasal Spray

Medicated Nasal Sprays(doctor-prescribed only) 

Disclaimer: Always consult your paediatrician before using medicated nasal drops or sprays for children. Even with saline drops or sprays, it is best to check with your doctor, especially for newborns and infants, to ensure proper use and safety. 

When Are Nasal Drops Needed?

Doctors may recommend nasal drops for babies and nasal sprays for kids in the following situations: 

Note: Saline nasal drops for babies do not cure the underlying illness, but they help relieve congestion and make breathing, feeding, and sleeping more comfortable. 

How to Use Nasal Drops for Babies and Kids

Using nasal drops correctly helps ensure they work safely and effectively. Follow these steps when using a nasal drop/spray for your child10,12:

Note: Always be gentle with newborns and infants. Avoid forcing the head back or inserting the dropper deep into the nostril.  

Safety and Dosage Guidelines on Using Nasal Drops for Infants

The safe use of nasal drops in newborns, infants, and children depends on following the correct dosage and frequency. Moreover, every child is different, and the right amount may vary depending on age, weight, and medical condition. 

Therefore, even if the recommended saline nasal drops dosage for babies is mentioned on the product packaging, parents should always follow their paediatrician’s instructions rather than relying on general guidance.  

Key point: Always consult your paediatrician for the correct type, dosage, and frequency of nasal drops or sprays for your child. Remember, safe handling and proper use are just as important as the medicine itself. 

Possible Side Effects of Nasal Drops

Nasal drops and sprays are generally safe, especially saline ones, but rarely some side effects may occur, particularly with medicated drops: 

1. Saline nasal drops side effects may include

2. Effects from prolonged or overuse of medicated drops may include

Tips for Parents

Here are some tips to help you use nasal drops and sprays safely for your baby: 

When to See a Doctor?

While nasal drops and sprays are generally safe and helpful, parents should consult a paediatrician if any of the following occur: 

Conclusion

Saline nasal drops and sprays are a safe, gentle, and effective way to relieve nasal congestion in babies and children. They help loosen and clear mucus, ease nasal blockage, and make breathing more comfortable (especially during colds, allergies, or dryness). 

When used correctly, nasal drops are highly safe and well-tolerated. However, it is important for parents to follow the right dosage, handling, and frequency, and to seek medical advice before using medicated drops or sprays. 

Remember, with proper use and guidance from your paediatrician, nasal drops can provide valuable relief, support restful sleep and feeding, and help little ones recover more comfortably and quickly. 

Frequently Asked Questions (FAQs)

Can I put nasal drops while the baby is sleeping? 

It is possible, but not always practical. For safety and effectiveness, it is usually easier when the baby is slightly upright or lying down with the head gently tilted back. This position helps the drops spread properly and reduces the risk of choking or discomfort11,12.

How many times a day can I give saline drops to my baby?

Saline drops are usually safe and can be used 2 to 3 times a day, which can be increased up to 6 times or as directed on the packaging. Always follow your paediatrician’s advice and avoid overuse13

Are nasal sprays safe for toddlers? 

Yes, saline nasal sprays are generally safe for toddlers (usually above 2 years). However, medicated sprays should only be used if prescribed by a doctor16.

Can saline nasal drops cause side effects? 

Saline drops are drug-free and rarely cause side effects. In some cases, babies may briefly sneeze or feel mild irritation, but this usually passes quickly11.

Do nasal drops cure a cold? 

No, nasal drops do not cure a cold. They help relieve congestion, clear mucus, and make breathing easier, but the cold itself will resolve naturally over time1,2.

References

  1. Chirico G, Beccagutti F. Nasal obstruction in neonates and infants. Minerva Pediatr. 2010 Oct;62(5):499-505. Available from:https://pubmed.ncbi.nlm.nih.gov/20940683/ 
  1. Chirico G, Quartarone G, Mallefet P. Nasal congestion in infants and children: a literature review on efficacy and safety of non-pharmacological treatments. Minerva Pediatr. 2014 Dec;66(6):549-57. Available from: https://pubmed.ncbi.nlm.nih.gov/25336097/ 
  1. U.S. Food and Drug Administration. Nasal Spray and Inhalation Solution, Suspension, and Spray Drug Products—Chemistry, Manufacturing, and Controls Documentation: Guidance for Industry[Internet]. U.S. Department of Health and Human Services; [cited 2025 Sep 10]. Available from: https://www.fda.gov/media/70857/download 
  1. Cleveland Clinic. Nasal Saline Irrigation for Babies [Internet]. Cleveland, OH: Cleveland Clinic; [cited 2025 Oct 7]. Available from: https://health.clevelandclinic.org/nasal-saline-irrigation-for-babies
  1. Cabaillot A, Vorilhon P, Roca M, Boussageon R, Eschalier B, Pereirad B. Saline nasal irrigation for acute upper respiratory tract infections in infants and children: A systematic review and meta-analysis. Paediatr Respir Rev. 2020 Nov;36:151-158. Available from: https://pubmed.ncbi.nlm.nih.gov/32312677/ 
  1. Deve L, Poduval J. Effectiveness of Over-The-Counter Intranasal Preparations: A Randomized Trial. Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1923-1928. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6848630/ 
  1. van Stralen KJ, van Tol JE, de Wildt SN, Becker ML, van Houten MA. Use of xylometazoline in hospitalised infants: is it safe? A retrospective cohort study. Arch Dis Child. 2023 Jan;108(1):62-66. Available from: https://pubmed.ncbi.nlm.nih.gov/36171065/ 
  1. Kim KT, Kerwin E, Landwehr L, Bernstein JA, Bruner D, Harris D, Drda K, Wanger J, Wood CC; Pediatric Atrovent Nasal Spray Study Group. Use of 0.06% ipratropium bromide nasal spray in children aged 2 to 5 years with rhinorrhea due to a common cold or allergies. Ann Allergy Asthma Immunol. 2005 Jan;94(1):73-9. Available from: https://pubmed.ncbi.nlm.nih.gov/15702820/ 
  1. World Health Organization. Pocket book of hospital care for children: guidelines for the management of common childhood illnesses [Internet]. WHO; [cited 2025 Sep 29]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK154448/ 
  1. Queensland Paediatric Emergency Care. Nasopharyngeal suctioning skill sheet [Internet]. Queensland Paediatric Emergency Care Working Group; [cited 2025 Sep 10]. Available from: https://www.childrens.health.qld.gov.au/__data/assets/pdf_file/0026/179720/nasopharyngeal-suctioning.pdf 
  1. Drug Office, Department of Health, Hong Kong. How to use nasal drops [Internet]. Hong Kong: Department of Health; 2022 Dec [cited 2025 Sep 10]. Available from: https://www.drugoffice.gov.hk/eps/do/en/consumer/news_informations/popular_drug_usages/how_to_use_nose_drops.html 
  1. GP Liaison and Integration Unit, Women’s and Children’s Hospital. How to use a nasal spray: Patient information sheet [Internet]. Women’s and Children’s Hospital; [cited 2025 Sep 10]. Available from: https://cdn.wchn.sa.gov.au/downloads/WCH/professionals/clinical-resources/GP-Collab-Care/WCHN-GP-Collaborative-Care-How-to-Use-a-Nasal-Spray-Fact-Sheet.pdf 
  1. Ramalingam S, Graham C, Oatey K, Rayson P, Stoddart A, Sheikh A, Cunningham S; ELVIS Kids Trial Investigators. Study protocol of the Edinburgh and Lothian Virus Intervention Study in Kids: a randomised controlled trial of hypertonic saline nose drops in children with upper respiratory tract infections (ELVIS Kids). BMJ Open. 2021 May 5;11(5):e049964. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8103393/ 
  1. Electronic Medicines Compendium (eMC). Patient Information Leaflet: Pseudoephedrine 60 mg Film-coated Tablets [Internet]. eMC; [cited 2025 Sep 10]. Available from: https://www.medicines.org.uk/emc/files/pil.6156.pdf 
  1. Wahid NWB, Shermetaro C. Rhinitis medicamentosa [Internet]. StatPearls Publishing; [updated 2023 Sep 4; cited 2025 Sep 10]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538318/ 
  1. U.S. Food and Drug Administration. Use caution when giving cough and cold products to kids [Internet]. U.S. Food and Drug Administration; [cited 2025 Sep 10]. Available from: https://www.fda.gov/drugs/special-features/use-caution-when-giving-cough-and-cold-products-kids 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof. 

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes. 

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Blue Baby Syndrome in Infants: Causes, Symptoms & Treatment 

Introduction

Blue Baby Syndrome is a condition where an infant’s skin, lips, or nails appear bluish because the blood cannot carry enough oxygen. This can happen from birth (congenital) or develop later (acquired) in life.  In this condition, haemoglobin (the oxygen-carrying part of red blood cells) gets converted into methaemoglobin, which cannot deliver oxygen efficiently to the tissues and leads to the bluish skin colour. Babies under six months are especially vulnerable to this because their organ systems are still developing.  

It is important for parents to understand this condition because early detection can prevent serious complications such as breathing difficulties or loss of consciousness. If left untreated, reduced oxygen supply to the brain and other vital organs can quickly make the condition life-threatening. By knowing the warning signs, causes, and available treatments, parents can respond quickly and ensure their baby receives the right care1,2

What Is Blue Baby Syndrome? 

Blue Baby Syndrome, also called infant methemoglobinemia, happens when a baby’s blood cannot carry enough oxygen to the body. This is because normal haemoglobin in red blood cells changes into methaemoglobin, which cannot transport oxygen like regular haemoglobin does. Even if the baby is breathing normally, the body’s tissues and organs may not get enough oxygen. In healthy blood, haemoglobin picks up oxygen from the lungs and carries it to all parts of the body. In Blue Baby Syndrome, some haemoglobin becomes methaemoglobin and loses its ability to carry oxygen. Babies are more sensitive to this because their red blood cells are still developing, and they have lower levels of certain enzymes that can convert methaemoglobin back into normal haemoglobin.  

When enough haemoglobin is affected, the body receives less oxygen than it needs. This is why the lips, skin, and sometimes nails can turn blue or purple. The colour change is a sign that oxygen delivery is reduced, which can affect important organs like the brain and heart if it continues for too long. The main issue in Blue Baby Syndrome is not with breathing itself but with the blood’s ability to carry oxygen properly. This can affect organs such as the brain and heart if oxygen delivery remains low for a long period1,3

Since Blue Baby Syndrome carries serious risks, we need to understand what causes it and address it early to prevent serious problems for the baby. 

What Causes Blue Baby Syndrome?

Blue Baby Syndrome is caused by various factors, and each cause plays a role in reducing the amount of oxygen reaching the baby’s body. These are: 

1. Heart Defects

Blue Baby Syndrome in infants is mainly caused by congenital heart defect, where a baby is born with a heart problem. This means the heart did not form normally before birth. Because of this, oxygen-rich blood and oxygen-poor blood may mix, or less blood may reach the lungs to pick up oxygen. Both situations lower the amount of oxygen reaching the body. A common example is Tetralogy of Fallot (TOF). This includes four heart issues together: 

These changes reduce oxygen delivery and can make the baby’s skin look bluish1

2. Nitrate Contamination in Water and Food

Another important reason babies can get Blue Baby Syndrome is when drinking water has too many nitrates. These come naturally from rain, plants, or animal waste, but the main problem is from chemical fertilisers, manure, or human and industrial waste. When there is too much nitrate, it can seep into wells, especially in villages where people use well water for drinking or making baby formula. If a baby drinks formula made with this water, the nitrates can change into nitrites, which stop the blood from carrying oxygen properly. Babies are more at risk because their blood had more affinity towards nitrates, their bodies are small, their digestive systems and enzymes are still developing, and they cannot handle this change well. Since nitrate contamination is not visible, the only way to know if water is safe is by testing it regularly3,4

3. Respiratory Conditions

Breathing problems can also cause Blue Baby Syndrome because they stop enough oxygen from reaching the blood. Some babies are born with blocked airways, such as choanal atresia (back of the nose is closed), Pierre Robin sequence (small jaw pushes the tongue back), laryngomalacia (soft voice box that collapses while breathing), tracheal stenosis (narrow windpipe), vocal cord paralysis (voice box does not move), or vascular rings (blood vessels pressing on the windpipe). Lung problems like pneumonia (lung infection), lung malformations (abnormal lung growth), underdeveloped lungs or conditions like Respiratory Distress Syndrome can also reduce oxygen saturation. Unlike nitrates, these problems do not change the blood itself but make it harder for oxygen to reach the blood, causing the baby to look blue5

4. Rare Blood Disorders

When the baby is born with a weak or missing enzyme called CYB5R or with a special type of haemoglobin called haemoglobin M, these changes stop the blood from carrying enough oxygen. In one form, only the red blood cells are affected, while in a more serious form, all the body’s cells are affected. Because the blood cannot deliver enough oxygen, the baby’s body may not get enough oxygen for normal functioning6

These conditions lower the amount of oxygen reaching the baby’s body. As a result, certain signs and changes in the skin, lips, and nails often appear, which help identify Blue Baby Syndrome. 

Symptoms of Blue Baby Syndrome

Symptoms of Blue Baby Syndrome can appear in different ways depending on how much oxygen the baby’s blood is carrying. Normally, only a tiny part of the blood has methaemoglobin, about 1%. If this increases, the blood cannot carry enough oxygen, and the baby starts showing signs like: 

Even a small rise in methaemoglobin can make the baby’s skin look bluish, which is called cyanosis. Cyanosis can occur when methaemoglobin reaches 1.5 g/dL compared to 5 g/dL of normal deoxygenated haemoglobin, showing the body is not getting enough oxygen1,7

Other common signs may include  

Detecting signs early and restoring oxygen can help prevent serious complications in the baby. 

Diagnosis

Blue baby syndrome cannot be confirmed just by looking at a baby’s skin colour. A proper medical check-up is needed. Doctors begin with a physical examination (a careful body check-up), checking the baby’s skin, lips, and tongue for bluish colour. They also listen to the heart and lungs (breathing organs) and look for signs of trouble such as rapid breathing (very fast breathing), nasal flaring (widening of the nose while breathing), or chest retractions (chest pulling in while breathing). These help them understand if the problem is linked to the heart, lungs, or blood1,3

Doctors may use a pulse oximeter (a small clip device put on finger or toe) to measure oxygen in the blood. If oxygen is low, they may order an arterial blood gas (ABG) test (a blood test to check oxygen and carbon dioxide levels). If methemoglobinemia is suspected, it can be detected by ABG along with other special tests like co-oximetry (a test that measures different forms of haemoglobin) or a direct methaemoglobin test can confirm it. 

When heart defects are suspected, doctors may suggest a chest X-ray (picture of chest), electrocardiogram/ECG (a test to check heartbeats), or echocardiogram (heart scan using sound waves). These tests show how the heart is working and whether blood is flowing normally1,6

It is important to remember that only a doctor can confirm the diagnosis. Parents should seek care quickly if their child shows blueness or breathing problems. 

Treatment Options

The treatment of blue baby syndrome depends on the underlying issue (main reason for the blueness). Doctors carefully assess the cause of the problem and then decide on the safest treatment. 

1. Heart-related causes

When the blueness is due to a heart defect (a problem in the structure of the heart), babies may be given medicines like prostaglandins (medicines that help keep certain blood vessels open) soon after birth. This allows more oxygen-rich blood to reach the body. Many babies will also require oxygen therapy (extra oxygen supply through a mask or tube) to improve breathing. In most cases, surgery (an operation to repair the heart problem) is needed during infancy so the baby’s heart can pump blood effectively1,3

2. Blood-related causes

If blue baby syndrome is caused due to nitrate poisoning (exposure to contaminated water or food), the treatment is different. The main medicine used is methylene blue (a hospital injection that helps blood carry oxygen properly again). In cases where methylene blue cannot be used, such as in babies with G6PD deficiency or those who react badly to the medicine, vitamin C (ascorbic acid) can help lower methaemoglobin and restore normal oxygen levels in the blood. Babies usually recover quickly once this is given. In mild cases, removing the contaminated source of water or food is often enough, as the blood slowly returns to normal within a few days1,3,10

3. Respiratory aid and supportive care

For babies with lung problems causing cyanosis (bluish skin or lips), doctors may help the baby breathe using assisted ventilation if there is trouble breathing. Oxygen can be given through a nasal tube (nasal cannula) or a small hood over the head. The oxygen amount is carefully controlled to keep blood oxygen at a safe level (around 90–95%).5 In very severe cases, rarely, doctors may use treatments such as exchange transfusion (replacing some of the baby’s blood with healthy blood) or provide high-flow oxygen (a stronger supply of oxygen in emergencies). These are only done in a hospital under strict medical supervision1,3

It is very important to remember that treatment is always chosen carefully for each baby’s condition. Parents should never attempt home remedies or give medicines on their own. Only trained doctors can decide the correct treatment and ensure the baby’s safety. 

Prevention & Parental Care

Blue baby syndrome may be prevented by safe water use, careful feeding, and proper maternal care during pregnancy. These measures help lower the chance of the condition in infants. 

1. Safe drinking water

safe drinking water

Formula for babies should be prepared only with water tested safe for nitrates. Private wells need yearly testing for nitrates and other impurities. If nitrate levels are higher than 10 mg/L, the water is unsafe for preparing infant formula or food4,11. In such cases, it is safer to use bottled water, public water supply, or deeper wells that usually have lower nitrate levels. Boiling water does not remove nitrates and may make the problem worse by concentrating them2,4

2. Prenatal and maternal care

prenatal and maternal care

Regular check-ups during pregnancy may help to find early risk for blue baby syndrome, like heart problems. Folic acid tablets help in the baby’s brain and heart growth. Smoking, alcohol and second-hand smoke reduce oxygen for the baby. Rubella vaccine before pregnancy lowers the chance of a baby’s heart defect. Good sugar control in the mother with diabetes also reduces the risk of the blue baby problem1

Following the above-mentioned can provide initial protection against blue baby syndrome. Parents also need to recognise warning signs in the baby and take them to the doctor on time. 

When to Seek Medical Help?

Blue baby syndrome can become serious quickly, so recognising warning signs is very important. 

When these warning signs appear, parents should not delay taking the baby to a doctor1,3

Also Read: Super Easy Yoga Poses for Kids to Try at Home

Conclusion

Blue baby syndrome is rare but can become serious fast. Understanding causes like heart problems, nitrate in water, blood or lung issues helps parents take care. Using safe water for formula, and proper care during pregnancy can lower the risk. Yet, it’s important to watch out for warning signs like blue skin, hard breathing, or excessive sleepiness if a child is unwell. Parents should take the baby to a doctor immediately when these signs appear so the baby can get the right treatment in hospital and stay safe. Being aware and following the care measures properly can help prevent serious problems and protect your baby’s health. 

Frequently Asked Questions (FAQs)

What is the blue baby syndrome caused by in water?

It mostly comes from nitrate in drinking water. These nitrates change to nitrites inside the body and block oxygen in the blood. This lowers oxygen supply and makes baby’s skin turn bluish or greyish3,4

Which drug causes blue baby syndrome?

Blue baby syndrome is rarely caused by drugs. The main medicine responsible is dapsone. Others that can sometimes lead to it include benzocaine, nitrate-containing solutions, and certain strong antibiotics. These medicines change the blood’s iron from working (ferrous) to non-working (ferric), reducing oxygen and making the baby appear blue12,13

What blood type causes blue babies?

No specific blood type by itself causes a baby to turn blue. A baby may appear bluish if there is Rh incompatibility, when an Rh-negative mother carries an Rh-positive baby. This can lead to haemolytic disease of the newborn (HDN) and low oxygen, making the skin, lips, or nails look blue. However, this blood type-related Rh incompatibility does not lead to blue baby syndrome, which usually refers to babies who are blue due to heart problems or other oxygen-related conditions5

Which element causes blue baby syndrome?

The main element linked is nitrogen from fertilisers or polluted water. In the body, nitrates turn into nitrites, which block haemoglobin. This cuts down oxygen supply, and slowly the baby shows blue or grey skin3,4

References 

  1. Vankodoth S, Boddu S, Gadila S, Mekala SC, Rao TR. Blue Baby Syndrome. Int J Pharm Pharm Res. 2025 Mar;31(3):418–22. Available from: https://ijppr.humanjournals.com/wp-content/uploads/2025/03/42.Vankodoth-Sireesha-1-Boddu-Shirisha2-Gadila-Sushma2-Mekala-Sai-Charitha2-Dr.T.-Rama-Rao3.pdf 
  2. Methemoglobinemia [Internet]. Health & Human Services. 2023 [cited 2025 Sep 24]. Available from: https://hhs.iowa.gov/health-prevention/providers-professionals/center-acute-disease-epidemiology/epi-manual/environmental-disease/methemoglobinemia 
  3. Majumdar D. The Blue Baby Syndrome – Nitrate Poisoning in Humans. Resonance J Sci Educ. 2003 Oct;8(10):20–30. Available from: https://www.ias.ac.in/article/fulltext/reso/008/10/0020-0030 
  4. Nitrate/Nitrite Toxicity: Initial Check | Environmental Medicine | ATSDR [Internet]. Cdc.gov. 2023 [cited 2025 Sep 24]. Available from: https://archive.cdc.gov/www_atsdr_cdc_gov/csem/nitrate-nitrite/initial_check.html 
  5. Steinhorn RH. Evaluation and Management of the Cyanotic Neonate. Clinical Pediatric Emergency Medicine [Internet]. 2008 Sep;9(3):169–75. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2598396/  
  6. Ludlow JT, Wilkerson RG, Nappe TM. Methemoglobinemia [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537317/ 
  7. Mahmoud Al-Absi. Blue Baby Syndrome. Pediatric Health [Internet]. 2013 Oct 12;8(9):339–404. Available from: https://www.researchgate.net/publication/342820505_Blue_Baby_Syndrome 
  8. NHS website. Congenital heart disease Symptoms [Internet]. nhs.uk. 2017. Available from: https://www.nhs.uk/conditions/congenital-heart-disease/symptoms/ 
  9. Ykeda DS, Lorenzi-Filho G, Lopes AAB, Alves RSC. Sleep in Infants with Congenital Heart Disease. Clinics [Internet]. 2009 Dec 1 [cited 2021 Oct 2];64(12):1205–10. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797590/  
  10. Keats KR, Robinson R, Patel M, Wallace A, Albrecht S. Ascorbic Acid for Methemoglobinemia Treatment: A Case Report and Literature Review. Journal of Pharmacy Practice [Internet]. 2023 Jul 8;8971900231188834. Available from: https://pubmed.ncbi.nlm.nih.gov/37421600/  
  11. Where We Stand: Testing of Well Water [Internet]. HealthyChildren.org. Available from: https://www.healthychildren.org/English/safety-prevention/all-around/Pages/Where-We-Stand-Testing-of-Well-Water.aspx 
  12. Dias E, Mahendrappa KB, Arkasali MR. Drugs causing methemoglobinemia in children. Curr Overv Dis Health. 2023;7(7):52–7. Available from: https://hal.science/hal-05153269v1  
  13. Andrade SJ, Anusha Raj K, Lewis LE, Jayashree Purkayastha, Gaurav Aiyappa. Neonatal Acquired Methemoglobinemia – Can Broad Spectrum Antibiotics be Implicated? The Indian Journal of Pediatrics. 2019 May 20;86(7):663–3. Available from: https://link.springer.com/article/10.1007/s12098-019-02978-5  

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Super Easy Yoga Poses for Kids to Try at Home

Introduction

Yoga is an ancient practice that combines gentle movements, breathing exercises, and mindfulness to enhance both physical and mental well-being1,2. For kids, this ancient practice can be a fun and playful way to stay active.  

Practising yoga regularly helps children improve their flexibility, balance, and coordination. Beyond the physical benefits of yoga for kids, it also supports concentration, relaxation, and energy management (skills that are especially valuable for their growth and daily activities)3

Therefore, as parents, you can feel assured that this guide introduces only simple, safe, and enjoyable yoga asanas for kids to try at home. The goal is to make yoga a fun habit that nurtures both body and mind. 

Why Should Kids Practice Yoga?

Childhood, known in Sanskrit as Balyavastha, is a period of learning, curiosity, and imagination. In ancient times, children lived in Gurukuls where yoga was part of daily life, helping them develop discipline, focus, and resilience. Today, children often lack this structured environment and face numerous distractions (such as technology, media, and busy lifestyles) that can cause stress or restlessness. Yoga provides a way to restore balance, nurturing both the body and mind4. Here are some benefits of yoga for kids: 

Important: Yoga is a wonderful addition to a healthy lifestyle, but it should not replace medical care or professional advice. 

How to Introduce Yoga to Kids

Introducing yoga to children is about making the practice simple, playful, and safe. Since childhood is a time of rapid growth (physically, mentally, and emotionally), yoga should be taught in a safe environment with a soft mat and constant adult supervision.  

​Yoga for children aged 3 to 10 years8

Yoga for children above 10 years8:

Note: Girls should avoid strenuous yoga during menstruation and instead practice relaxation techniques.   

Super Easy Yoga Poses for Kids

Yoga practices instil important life values such as discipline (Yama), self-care (Niyama), calmness, and self-awareness. They encourage children to choose healthy habits and positive attitudes, which guide them toward growth and independence4. Parents can help their children practice daily using these simple yoga steps for kids9

1. Palm Tree Pose (Tadasana)

a kid doing palm tree pose tadasana

Benefits: Improves posture, strengthens legs, stretches shoulders, and may support height growth. 

2. Tree Pose (Vrikshasana)

a kid doing tree pose virkshasana

Benefits: Builds balance, focus, and leg strength. 

3. Mountain Pose (Parvatasana)

a kid doing mountain pose parvatasana

Benefits: Strengthens arms, shoulders, and legs; stretches spine. 

4. Triangle Pose (Trikonasana)

a kid doing triangle pose trikonasana

Benefits: Improves flexibility, strengthens legs, and enhances concentration. 

5. Cat Stretch (Marjariasana)

a kid doing cat stretch pose marijariasana

Benefits: Makes the spine flexible, relieves stiffness, and supports digestion. 

6. Rabbit Pose (Shashakasana / Child’s Rest)

a kid doing rabbit pose shashakasana/ child rest

Benefits: Calms the mind, reduces stress, and improves memory and focus. 

7. Cobra Pose (Saral Bhujangasana)

a kid doing cobra pose bhujangasana

Benefits: Strengthens the back, opens the chest, and relieves fatigue. 

8. Bow Pose (Dhanurasana)

a kid doing bow pose dhanurasana

Benefits: Improves flexibility, strengthens spine, energises body. 

9. Bridge Pose (Setubandhasana)

a kid doing bridge pose setubandhasana

Benefits: Strengthens the back, improves digestion, and relieves anxiety. 

10. Starfish Relaxation (Shavasana)

a kid doing starfish relaxation shavasana

Benefits: Relieves stress, improves focus, and relaxes the mind and body. 

Note: Children should always practice yoga under adult supervision, and if needed, with the guidance of a trained yoga professional to ensure safety and proper technique. 

Tips for Parents to Keep Kids Engaged

Yoga can be a wonderful experience for kids when it feels playful and enjoyable. Here are some tips to help parents while encouraging yoga poses for kids: 

By making yoga asanas for kids enjoyable, storytelling-based, and non-competitive, parents and teachers can help kids see yoga not just as exercise but also as a joyful way to live with balance, confidence, and inner peace. 

Also Read: Stomach Pain in Kids: Causes, Home Remedies, and Treatment Options

Safety & Precautions

While yoga is safe and beneficial for children, it is important to follow a few precautions to make the practice enjoyable and risk-free2,8

Note: Yoga should always be practised on an empty or light stomach and under the guidance of a trained teacher. If a child feels discomfort, stop immediately and provide attention or medical help if necessary. 

Also Read: Baby Weight Gain Foods & Growth Tips Every Parent Should Know

Conclusion

Yoga is a wonderful way for children to stay active, healthy, and calm while having fun. It not only supports physical growth through better strength, flexibility, and balance but also helps kids develop focus, emotional control, and relaxation skills.  

Therefore, practising yoga together at home can become a joyful family activity, strengthening bonds while encouraging healthy habits. It is also important to keep in mind that parents do not need to aim for perfect yoga poses for kids; the key is to keep sessions safe, playful and consistent. Yoga can easily become a part of a child’s daily routine, offering lifelong benefits for both body and mind with a little patience and creativity. 

Frequently Asked Questions (FAQs)

What age is it good for kids to start yoga? 

Any age is a good age to start yoga. Even toddlers can start by kicking and stretching and kids as young as 3 years can do simple, playful poses. However, structured practice is more suitable from around age 10 and above8

Is yoga healthy for kids? 

Yes, yoga is safe and healthy when age-appropriate poses are chosen and practised under adult supervision. It supports physical fitness, emotional balance, and overall well-being1,10

Can yoga improve focus and concentration in kids? 

Yes, breathing exercises and mindful movements in yoga help children calm their minds, which can improve focus, attention span, and learning2,10

Do kids need a yoga mat or special equipment? 

A soft yoga mat is enough2. No special equipment is required, just comfortable clothing and a safe space. 

Can yoga help kids with stress or anxiety? 

Yes, gentle yoga and breathing exercises teach kids how to relax and release tension, making them feel calmer and more confident2,9

References

  1. Woodyard C. Exploring the therapeutic effects of yoga and its ability to increase quality of life. Int J Yoga. 2011 Jul;4(2):49-54. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3193654/ 
  2. Wyoming Department of Education. Yoga for kids [Internet]. Wyoming Department of Education; [cited 2025 Sep 8]. Available from: https://edu.wyoming.gov/downloads/vision-outreach/svi_wreic_2013_yoga_for_kids.pdf 
  3. Hagen I, Nayar US. Yoga for Children and Young People’s Mental Health and Well-Being: Research Review and Reflections on the Mental Health Potentials of Yoga. Front Psychiatry. 2014 Apr 2;5:35. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3980104/ 
  4. MDNIY (Ministry of AYUSH). Yoga for Children [Internet]. MDNIY; [cited 2025 Sep 8]. Available from: https://www.yogamdniy.nic.in/files/pdf/YogaChildren.pdf 
  5. National Commission for Protection of Child Rights (NCPCR). Guidelines for Child Yoga [Internet]. NCPCR; [cited 2025 Sep 8]. Available from: https://ncpcr.gov.in/uploads/165753753662cc0400e2d79_guidelines-for-child-yoga-1615-kb.pdf 
  6. Khajuria A, Kumar A, Joshi D, Kumaran SS. Reducing Stress with Yoga: A Systematic Review Based on Multimodal Biosignals. Int J Yoga. 2023 Sep-Dec;16(3):156-170. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10919405/ 
  7. Martín-Rodríguez A, Gostian-Ropotin LA, Beltrán-Velasco AI, Belando-Pedreño N, Simón JA, López-Mora C, Navarro-Jiménez E, Tornero-Aguilera JF, Clemente-Suárez VJ. Sporting Mind: The Interplay of Physical Activity and Psychological Health. Sports (Basel). 2024 Jan 22;12(1):37. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10819297/ 
  8. Vikaspedia. Guidelines for Child Yoga [Internet]. Vikaspedia; [cited 2025 Sep 8]. Available from: https://health.vikaspedia.in/viewcontent/health/ayush/yoga-1/guidelines-for-child-yoga?lgn=en 
  9. Vikaspedia. Yoga for Children of Age 3–6 Years: Yoga Asanas for Children [Internet]. Vikaspedia; [cited 2025 Sep 8]. Available from: https://health.vikaspedia.in/viewcontent/health/ayush/yoga-1/yoga-for-children-of-age-3-6-years/yoga-asanas-for-children?lgn=en 
  10. Rashedi RN, Rowe SE, Thompson RA, Solari EJ, Schonert-Reichl KA. A Yoga Intervention for Young Children: Self-Regulation and Emotion Regulation. J Child Fam Stud. 2021;30(8):2028-2041. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8188743/ 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Breast Cancer: What It Is, Types, Early Signs, Treatment & Prevention

Introduction

Breast cancer is a disease where the cells and tissues in the breast change and grow out of control1. This extra growth can form a lump called a tumour. If the tumour keeps growing, it can spread to nearby breast tissue, reach the lymph nodes, and move to other parts of the body2. Breast cancer is the second most common cancer in women, after skin cancer3

Getting diagnosed early often leads to more effective treatment. In most cases, screening tests like mammograms can detect breast cancer even before a lump forms. Around 99 in 100 women survive 5 years or more when breast cancer is caught early. Survival drops to about 87 in 100 if it spreads nearby, and to about 33 in 100 if it spreads further4,5. After diagnosis, doctors choose treatment by looking at how advanced the cancer is, what signals the cancer cells show (like hormones or HER2), and the person’s overall health. Treatment may include surgery, radiation, or medicines2

In this blog, we will see what breast cancer is, its types, early signs, and how to lower the risk or manage it. 

What Is Breast Cancer?

The breast is an organ in the front of the chest that makes milk after childbirth. It is more developed in women, while in men it stays smaller6

Breast cancer happens when cells in the breast grow out of control. It usually begins in the milk ducts (tiny tubes that carry milk) or in the lobules (glands that make milk). Sometimes the cancer stays in place, but if it spreads into nearby tissue, it can grow and move to other parts of the body. If the cancer cells stay inside the duct, it is called ductal carcinoma in situ. If they break through the duct wall and spread into nearby tissue, it is called invasive ductal carcinoma. Sometimes, cancer can also begin in the lobules. When it spreads from the lobules into nearby tissue, it is called invasive lobular carcinoma7,9

Breast cancer is one of the most common cancers worldwide, affecting about 2.3 million women each year. In India, it accounts for about 1 in 8 cancer cases, with around 1.6 lakh women diagnosed in 2020. Breast cancer survival rates depend on how early it is found and treated; about 66 out of 100 women in India live at least five years after diagnosis10,12

Causes & Risk Factors of Breast Cancer

The reasons for breast cancer could be due to hereditary or lifestyle-related factors. 

Other causes of breast cancer are: 

The modifiable risk factors of breast cancer are: 

Types of Breast Cancer

There are different types of breast cancer and they vary in tumour behaviour, grade, and treatment response. 

1. Non-invasive breast cancer

2. Invasive breast cancer

Breast cancer is also divided into different subtypes depending on certain proteins called receptors. These include oestrogen and progesterone receptors and another called HER2. Some breast cancers use these proteins to grow faster. 

Breast Cancer Stages

Breast cancer is divided into 5 stages based on how much the cancer has grown and its spread to other parts. 

Doctors use the TNM system to decide the cancer stage. T stands for the size of the tumour, N shows if lymph nodes have cancer, and M indicates whether the cancer has spread to distant parts. 

The higher the stage, the more advanced the cancer is. Staging the cancer helps to formulate the best treatment plan and predict how likely it is that the patient will recover. It also helps track how the cancer changes over time during breast cancer treatment and predict the outcomes18

Early Signs & Symptoms

Many individuals who have breast cancer don’t show symptoms in the early stage, so how to identify breast cancer? You can check for lumps in the breasts yourself or get them checked during regular checkups or screening from a doctor. Symptoms may be seen only when the cancer grows or spreads. 

The common signs and symptoms of early and advanced breast cancer are: 

The table below gives more clarity on breast cancer symptoms in early and advanced stages19,20

Symptoms Early Stage Advanced Stage 
Lump or thickening in breast Yes Yes 
Skin changes (redness, dimpling) Yes Yes 
Nipple changes (pain, discharge) Yes Yes 
Swollen lymph nodes No Yes 
Breast pain Rare Yes 
Bone pain or aches No Yes (bone involvement) 
Weight loss or tiredness No Yes (liver involvement) 
Shortness of breath or cough No Yes (lung involvement) 
Headache or vision changes No Yes (brain involvement) 

How to Check for Breast Cancer

Breast cancer can be checked by different methods. You can check your breasts for changes yourself, or a doctor can do a breast examination to feel for any lumps or unusual signs. 

1. Checking Your Breasts for Changes

If you notice any changes in these areas, see a doctor promptly so that even small changes can be checked thoroughly. 

2. Clinical Breast Examination

This is done by a doctor who will gently feel and check the breasts and underarms for any lumps or unusual signs. They carefully look for anything different in the breast like changes in size, shape, or texture23

There are certain screening tests available to check for breast cancer, as below: 

3. Imaging Tests

Besides exams done by you or your doctor, there are imaging tests that can give a clearer picture of breast cancer. 

The type of screening required for breast cancer depends on your medical condition and risks, as the doctor advises. It is recommended that women aged 40 to 74 years with average breast cancer risk get a mammogram every 2 years. Those who have risks like BRCA1 and BRCA2 gene mutation, or have had chest radiation at a young age, need more frequent screening as advised by the doctor21,23

Is Breast Cancer Curable?

The treatment of breast cancer depends on the stage of breast cancer. No two patients are exactly the same, and treatment and responses to treatment can vary a lot. 

Around the world, about 92 out of 100 women live at least 5 years after being diagnosed with breast cancer. In India, the numbers are lower because many women find out late or don’t get full treatment. 

If breast cancer is found early and before it spreads to other parts, the survival rate increases. Therefore, regular checks and timely screening for women at increased risk can help find cancer early. In India, many women do not get routine mammograms, so doctors mainly use careful breast exams and special imaging tests to detect cancer early and make it easier to treat24,26

Breast Cancer Treatment Options

There are various treatment options for breast cancer, the choice of which depends on the type of breast cancer and its stage, as follows: 

Some patients may receive a combination of therapies to improve their chances of recovery. When breast cancer is diagnosed early, treatment can be planned to get the best outcome and help prevent cancer from coming back2,8

How to Prevent Breast Cancer

Breast cancer cannot be completely prevented, but healthy lifestyle choices and certain measures may help lower the risk. These include: 

When to See a Doctor?

You must see a doctor if you have any of these signs, which could possibly indicate breast cancer: 

Conclusion

Breast cancer can be managed well if found in the early stages. Knowing the early signs and acting promptly helps early detection and treatment initiation. Many types of breast cancer respond well to advanced medicines, especially when diagnosed early, leading to better outcomes and improved recovery. 

Frequently Asked Questions (FAQs)

What are the first signs of breast cancer? 

Most people don’t show any early signs of breast cancer. As the cancer grows, you might feel a lump in the breast. Other signs include changes in breast size or shape, nipple redness or sores, skin dimpling, swelling in the armpit, or persistent breast pain not related to periods8,27

How is breast cancer diagnosed? 

Breast cancer is diagnosed by checking the breast for lumps or changes, getting imaging tests like mammograms, and confirming with a biopsy27.  

Is breast cancer hereditary? 

Some types of breast cancer are hereditary. The BRCA1 and BRCA2 genes, which control cell growth, can undergo mutations causing cancer. The child can get cancer if it is passed from parents, but not everyone with this gene will develop cancer12

How to reduce breast cancer risk? 

You cannot completely prevent breast cancer, but healthy eating, exercise, and limiting alcohol use can lower the risk. High-risk individuals can talk to a doctor about hormone therapy or surgery to reduce cancer risk27

References

  1. MedlinePlus. Breast Cancer [Internet]. Medlineplus.gov. National Library of Medicine; 2019. Available from: https://medlineplus.gov/breastcancer.html 
  2. World Health Organization. Breast cancer [Internet]. World Health Organization. 2024. Available from: https://www.who.int/news-room/fact-sheets/detail/breast-cancer 
  3. National Cancer Institute. Breast Cancer [Internet]. National Cancer Institute. Cancer.gov; 2019. Available from: https://www.cancer.gov/types/breast 
  4. CDC. U.S. Cancer Statistics Breast Cancer Stat Bite [Internet]. United States Cancer Statistics. 2024. Available from: https://www.cdc.gov/united-states-cancer-statistics/publications/breast-cancer-stat-bite.html 
  5. National Cancer Institute. Female Breast Cancer – Cancer Stat Facts [Internet]. SEER. 2024. Available from: https://seer.cancer.gov/statfacts/html/breast.html 
  6. Bazira PJ, Ellis H, Mahadevan V. Anatomy and physiology of the breast. Surgery (Oxford). 2021 Dec;40(2). Available from: https://www.sciencedirect.com/science/article/abs/pii/S026393192100260X  
  7. Centers for Disease Control and Prevention. Breast Cancer Basics [Internet]. Breast Cancer. 2024. Available from: https://www.cdc.gov/breast-cancer/about/index.html 
  8. Alkabban FM, Ferguson T. Breast Cancer [Internet]. www.ncbi.nlm.nih.gov. StatPearls Publishing; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482286/?report=reader 
  9. Łukasiewicz S, Czeczelewski M, Forma A, Baj J, Sitarz R, Stanislawek A. Breast cancer—epidemiology, Risk factors, classification, Prognostic markers, and Current Treatment Strategies—an Updated Review. Cancers [Internet]. 2021;13(17):4287. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8428369/ 
  10. Mehrotra R, Yadav K. Breast cancer in India: Present scenario and the challenges ahead. World Journal of Clinical Oncology [Internet]. 2022 Mar 24;13(3):209–18. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966510/ 
  11. Pillai RN, Alex A, Narassima M.S, Verma V, Ajil Shaji, Keechilat Pavithran, et al. Economic burden of breast cancer in India, 2000–2021 and forecast to 2030. Scientific Reports [Internet]. 2025 Jan 8;15(1). Available from: https://www.nature.com/articles/s41598-024-83896-1#Sec13 
  12. Obeagu EI, Obeagu GU. Breast cancer: A review of risk factors and diagnosis. Medicine [Internet]. 2024 Jan 19;103(3). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10798762/#sec-a.d.btitle 
  13. Centers for Disease Control and Prevention. Breast cancer risk factors [Internet]. CDC. 2024. Available from: https://www.cdc.gov/breast-cancer/risk-factors/index.html 
  14. Udaya Kumar D. Issue 3 www.jetir.org(ISSN-2349-5162). JETIR2403572 Journal of Emerging Technologies and Innovative Research [Internet]. 2024 [cited 2025 Aug 11];11. Available from: https://www.jetir.org/papers/JETIR2403572.pdf 
  15. Yang C, Lei C, Zhang Y, Zhang J, Ji F, Pan W, et al. Comparison of Overall Survival Between Invasive Lobular Breast Carcinoma and Invasive Ductal Breast Carcinoma: A Propensity Score Matching Study Based on SEER Database. Frontiers in Oncology [Internet]. 2020 Dec 22;10. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783385/ 
  16. Yersal O, Barutca S. Biological Subtypes of Breast cancer: Prognostic and Therapeutic Implications. World Journal of Clinical Oncology. 2014;5(3):412. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4127612/ 
  17. Cancer Australia. Stages of breast cancer [Internet]. Cancer Australia. 2024. Available from: https://www.canceraustralia.gov.au/cancer-types/breast-cancer/how-breast-cancer-diagnosed/stages-breast-cancer 
  18. Teichgraeber DC, Guirguis MS, Whitman GJ. Breast Cancer Staging: Updates in the AJCC Cancer Staging Manual 8th Edition and Current Challenges for Radiologists, From the AJR Special Series on Cancer Staging. American Journal of Roentgenology. 2021 Feb 17;217(2). Available from: https://www.ajronline.org/doi/10.2214/AJR.20.25223  
  19. Centers for Disease Control and Prevention. Symptoms of Breast Cancer [Internet]. Breast Cancer. 2024. Available from: https://www.cdc.gov/breast-cancer/symptoms/index.html 
  20. National Breast Cancer Foundation. Stage 4 (advanced or metastatic) breast cancer | NBCF [Internet]. National Breast Cancer Foundation (NBCF) | Donate Online. 2025. Available from: https://nbcf.org.au/about-breast-cancer/diagnosis/stage-4-advanced-or-metastatic-breast-cancer/ 
  21. Centers for Disease Control and Prevention. Screening for breast cancer [Internet]. Breast Cancer. 2024. Available from: https://www.cdc.gov/breast-cancer/screening/index.html 
  22. NHS. How to check your breasts or chest [Internet]. nhs.uk. 2024. Available from: https://www.nhs.uk/tests-and-treatments/how-to-check-your-breasts-or-chest/ 
  23. National Cancer Institute. Breast cancer screening [Internet]. National Cancer Institute. Cancer.gov; 2023. Available from: https://www.cancer.gov/types/breast/patient/breast-screening-pdq 
  24. CDC. U.S. Cancer Statistics Breast Cancer Stat Bite [Internet]. United States Cancer Statistics. 2024. Available from: https://www.cdc.gov/united-states-cancer-statistics/publications/breast-cancer-stat-bite.html 
  25. National Cancer Institute. Female Breast Cancer – Cancer Stat Facts [Internet]. SEER. 2024. Available from: https://seer.cancer.gov/statfacts/html/breast.html 
  26. Mehrotra R, Yadav K. Breast cancer in India: Present scenario and the challenges ahead. World Journal of Clinical Oncology [Internet]. 2022 Mar 24;13(3):209–18. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966510/ 
  27. Healthdirect Australia. Breast cancer [Internet]. www.healthdirect.gov.au. 2019. Available from: https://www.healthdirect.gov.au/breast-cancer 
  28. CDC. Reducing Risk for Breast Cancer [Internet]. Breast Cancer. 2024. Available from: https://www.cdc.gov/breast-cancer/prevention/index.html 
  29. National Cancer Institute. Breast cancer prevention [Internet]. Cancer.gov; 2021. Available from: https://www.cancer.gov/types/breast/patient/breast-prevention-pdq 
  30. Breast Cancer – ICMR – National Institute of Cancer Prevention and Research [Internet]. Cancerindia.org.in. 2015 [cited 2025 Aug 11]. Available from: https://cancerindia.org.in/breast-cancer/#1715844966007-b672ee3f-48d7 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Zepbound vs Wegovy: Side Effects, Effectiveness and More!

Introduction

Obesity is a rising global health concern. Global reports show that hundreds of millions of adults have been affected in recent decades. These numbers indicate the magnitude of obesity, which is medically defined as having a body mass index (BMI) of more than or equal to 30 kg/m² in adults. It is a significant lifestyle-related risk factor as obesity increases the odds of osteoarthritis, cardiovascular disease, stroke, type 2 diabetes (T2D), and metabolic dysfunction-associated steatotic liver disease ([MASLD], a liver condition associated with overweight and diabetes), among many other life-threatening diseases.  

With obesity becoming a major health issue, there is a growing interest in new treatment options. Zepbound (tirzepatide) and Wegovy (semaglutide) are two medicines that have come under the spotlight recently. Wegovy is FDA- and EMA-approved at 2.4 mg weekly for chronic weight management. Zepbound is FDA-approved for obesity (in 2023), but availability and approval may differ across countries (not yet EMA-approved as of 2025). They are both GLP-1 receptor agonists (a substance that acts like the natural human GLP-1 hormone and turns on a receptor in the body). Zepbound is a dual GLP-1/GIP agonist, while Wegovy is a GLP-1 agonist1

Overview of Wegovy and Zepbound

Wegovy and Zepbound are the brand names of medicines approved for chronic weight management. Wegovy contains semaglutide and Zepbound contains tirzepatide. Both are injectables used along with a calorie-deficient diet and regular exercise. The FDA had earlier approved semaglutide and tirzepatide for T2D under the brand names Ozempic and Mounjaro, respectively2,3

Brand name Generic name Pronunciation Manufacturer Approved uses 
Wegovy Semaglutide Wee-GOH-vee Novo Nordisk 
For weight management in obese/overweight people (lower risk of cardiovascular problems) 
Zepbound tirzepatide ZEPH-bownd Eli Lily and company 
For weight management in obese/overweight people Obstructive sleep apnoea 

Table 1: Overview on Wegovy and Zepbound 

How Wegovy and Zepbound work

Wegovy’s active ingredient, semaglutide, works as a GLP-1 receptor agonist. It lowers blood sugar and promotes weight management by activating GLP-1 receptors in the gut, pancreas, and brain, as follows. 

The active ingredient in Zepbound, tirzepatide, is a dual agonist that activates both GLP-1 and GIP receptors.  

How the medicines affect appetite, satiety (feeling full), and metabolism: 

GLP-1 agonists like semaglutide and dual agonists like tirzepatide reduce hunger, help to maintain the feeling of being full last longer, and steady blood sugar. They curb appetite through their effect on the brain, slow digestion to boost satiety, and improve insulin balance in the pancreas, thus improving weight control, blood sugar regulation, and metabolic parameters (e.g., lipids, insulin sensitivity, and liver fat reduction). Clinical trials (e.g., SURMOUNT-1 vs STEP) show that tirzepatide generally achieves greater weight loss than semaglutide (~20% vs ~15% body weight) at highest doses3,4

Dosage and Administration of Wegovy and Zepbound

Wegovy

Weeks Dosage 
1-4 0.25 mg per week 
5-8 0.5 mg per week 
9-12 1 mg per week 
13-16 1.7 mg per week 
17 onward 2.4 mg per week (maintenance dose) 

Table 2: Dose escalation schedule 

Zepbound

Weeks Dosage 
1-4 2.5 mg per week 
5-8 5 mg per week 
9-12 7.5 mg per week 
13-16 10 mg per week 
17-20 12.5 mg per week 
21 onward 15 mg per week (maintenance dose) 

Table 3: Dose escalation schedule 

Effectiveness of Wegovy vs Zepbound

Evidence from clinical trials: In large clinical trials (STEP trials for semaglutide and SURMOUNT for tirzepatide), adults with overweight or obesity were treated with either Wegovy (semaglutide, up to 2.4 mg weekly) or Zepbound (tirzepatide, up to 10–15 mg weekly). Both medicines supported significant weight management, but participants taking the highest doses of Zepbound tended to lose more weight than those on Wegovy. This benefit was seen in people with and without diabetes. Zepbound had slightly higher rates of nausea, vomiting, and diarrhoea than Wegovy, particularly during dose escalation. 

Apart from clinical trials, some real-world retrospective cohort studies (like one study published in JAMA 2023) also compared the two drugs. These showed similar patterns, but because they relied on clinic records, the data wasn’t perfect. Parameters like the exact timing of weigh-ins, side effect tracking, and patient motivation weren’t always clear, and the participants did not fully represent the whole U.S. 

In the trials, participants with type 2 diabetes had separate, dedicated trials (STEP 2 for Wegovy, SURMOUNT-2 for Zepbound). People with depression could still participate, unless their condition was severe or unstable7

Average percentage weight loss comparison  

Patient group Semaglutide (0.5 mg, T2D dose) Tirzepatide (5 mg, T2D dose) Semaglutide (2.4 mg, obesity dose) Tirzepatide (10 mg, obesity dose) 
With T2D Around 58% lost at least 5% of weight Around 69% lost at least 5% of weight Around 73% lost at least 5% of weight Around 82% lost at least 5% of weight 
Without T2D Too few patients on these lower doses to measure reliably Too few patients on these lower doses to measure reliably Around 92% lost at least 5% of weight Around 96% lost at least 5% of weight 

Table 4: Average percentage weight loss comparison 

T2D = Type 2 diabetes 

Factors that may affect the outcomes

Zepbound vs Wegovy Side Effects

Wegovy

The side effects associated with Wegovy are discussed in Table 5. 

Side effects Description Precaution 
Thyroid tumours Risk observed in animals; uncertain in humans  Do not administer in patients with medullary thyroid carcinoma/multiple endocrine neoplasia type 2; pay attention to neck swelling or hoarseness 
Pancreatitis Inflammation of pancreas Stop usage if suspected; do not proceed if diagnosed with pancreatitis 
Gallbladder disease Higher risk of gallstones and gallbladder infection Check for gallbladder problems if symptoms occur. 
Low blood sugar More common in people with type 2 diabetes. Monitor glucose and adjust other diabetes medications 
Kidney injury Due to dehydration from vomiting/diarrhoea Stay hydrated and monitor kidney function 
Allergic reactions Anaphylaxis, swelling (rare but serious) Discontinue usage if reaction occurs and avoid if there is a history of allergy to semaglutide. 
Eye problems May worsen diabetic retinopathy (eye condition caused by diabetes) in some patients Monitor vision, especially if history of retinopathy 
Increased heart rate Small rise in resting heart rate reported Monitor heart rate; stop if persistent increase 
Suicidal thoughts Mood changes or suicidal behaviour possible Monitor mental health; avoid in patients with history of suicidal tendencies 
Immunogenicity About 3% of patients developed anti-drug antibodies, with 1.6% persistent; no impact on weight management, drug levels, or side effects was observed. – 

Table 5: Wegovy side effects (less common but serious risks) 

Zepbound

Other side effects of Zepbound are discussed in Table 6. 

Side effect Description  
Gastrointestinal Nausea, vomiting, diarrhoea, constipation, mostly mild/moderate; sometimes causes dehydration or low blood pressure 
Acute kidney disease Rare, sometimes linked to gastrointestinal issues or dehydration 
Gallbladder disease Cholecystitis and gallbladder events were slightly higher 
Pancreatitis Low incidence, mild increases in amylase/lipase 
Hypoglycaemia Lower blood sugar levels when used with insulin or other medicines that increase insulin levels 
Eye problems May worsen diabetic retinopathy in some patients 
Psychiatric disorders Mood changes or suicidal behaviour possible 
Increase in heart rate Small rise in resting heart rate reported 
Immunogenicity 64.5% patients developed antibodies, and some had hypersensitivity or injection site reactions 

Table 6: Zepbound side effects (less common but serious risks) 

Both Zepbound and Wegovy have similar side effects but with slight variation. Below is a table comparing side effects of both weight management drugs5,6

Side effect Zepbound Wegovy 
Gastrointestinal Nausea, vomiting, diarrhoea, constipation, abdominal pain, dyspepsia, flatulence, reflux, fatigue, dizziness Nausea, vomiting, diarrhoea, constipation, abdominal pain, dyspepsia, fatigue, dizziness, flatulence, reflux, gastroesophageal reflux disease, hair loss 
Kidney injury Rare; sometimes linked to gastrointestinal issues/dehydration Due to dehydration from vomiting/diarrhoea 
Gallbladder disease Slightly higher risk of gallstones/cholecystitis Higher risk of gallstones and gallbladder infection 
Pancreatitis Low incidence, mild amylase/lipase increase Inflammation of pancreas 
Hypoglycaemia Lower blood sugar levels when used with insulin or other medicines that increase insulin levels More common in type 2 diabetes 
Eye problems May worsen diabetic retinopathy May worsen diabetic retinopathy 
Psychiatric disorders Mood changes, suicidal behaviour possible Suicidal thoughts or mood changes possible 
Heart rate Small rise reported Small rise reported 
Immunogenicity/ Allergic reactions 64.5% developed antibodies; some hypersensitivity/injection site reactions 2.9% had confirmed anti-drug antibodies 
Thyroid C-cell Tumours Risk observed in animals; uncertain in humans; avoid in medullary thyroid carcinoma/multiple endocrine neoplasia type 2 patients Risk observed in animals; uncertain in humans; avoid in medullary thyroid carcinoma/multiple endocrine neoplasia type 2 patients 

Table 7: Comparison between side effects of Wegovy and Zepbound 

Managing side-effects safely 

When to call the doctor

Call the doctor in case of: 

Most side effects get better with time. Follow the doctor’s plan and check in regularly for optimum results. 

Other Potential Health Benefits

Zepbound

Wegovy

Why additional benefits may influence the choice

Many people living with obesity also deal with other health conditions, so choosing a medication that addresses more than one issue can improve overall health and reduce the need for multiple treatments. Wegovy has been shown to lower the risk of heart attack and stroke and may also support certain liver conditions. It may also be the preferred medicine in individuals at high risk of T2D.1,2 Zepbound, on the other hand, can help improve obstructive sleep apnoea, a condition where breathing repeatedly stops during sleep6. For this reason, it is important to consider not only how much weight can be lost but also the added health benefits each treatment may provide. 

Eligibility for Wegovy and Zepbound

The following table lists the eligibility criteria for both Wegovy and Zepbound5,6

Categories Wegovy Zepbound 
Age group Adults (18 years or older) and adolescents ≥12 years  Adults 
The drug can be prescribed to Adults with overweight and ≥1 comorbidity and adolescents ≥12 yrs with obesity Adults with overweight and ≥1 comorbidity 
Other purposes Reduce risk of cardiovascular events Treat moderate-to-severe obstructive sleep apnoea 
Safety warnings Do not use with other semaglutide-containing products or any GLP-1 receptor agonist Do not use with other tirzepatide-containing products or any GLP-1 receptor agonist 
Contraindications Personal or family history of medullary thyroid carcinoma People with Multiple Endocrine Neoplasia syndrome type 2 Allergic reaction to semaglutide. Personal or family history of medullary thyroid carcinoma People with Multiple Endocrine Neoplasia syndrome type 2 Allergic reaction to tirzepatide. 

Table 8: Eligibility for Wegovy and Zepbound 

Cost of Wegovy and Zepbound

Wegovy is available in pharmacies across India (imported)from the end of June 2025, but Zepbound has not yet been introduced in India. Below is the price list of Wegovy across different doses. 

Dose Monthly price (Rs) Price per dose (Rs) 
0.25 mg Rs 17,345 Rs 4,366 
0.50 mg Rs 17,345 Rs 4,366 
1.00 mg Rs 17,345 Rs 4,366 
1.75 mg Rs 24,280 Rs 6,070 
2.40 mg Rs 26,015 Rs 6,503 

Table 9: cost per dose for Wegovy (imported) 

Factors that affect the cost 

Accessibility challenges in India (Only Wegovy)

Why affordability matters in long term use

Switching from Wegovy to Zepbound or Vice Versa

Conclusion

Wegovy and Zepbound are both promising medicines used to manage overweight and obesity. The key difference is that while both act on GLP-1 receptors, Zepbound also targets GIP receptors. The choice between them depends entirely on a patient’s health needs. It is advisable to research both medicines and consult a doctor before making a decision. Regular check-ups and monitoring of symptoms are vital. It is important to remember that there is no solution that may fit everyone. What works best often depends on health history, side effect tolerance, availability, and cost. 

The safest step is to consult a qualified healthcare professional before making any decision. A doctor can assess medical history, existing health conditions, and long-term goals to recommend the most suitable treatment. 

Frequently Asked Questions (FAQs)

Which is more effective for weight management? 

In the comparison of Wegovy vs Zepbound weight loss, both semaglutide and tirzepatide led to significant reductions, with tirzepatide showing greater results at 3, 6, and 9 months. The study included real patients, but results may not be exact because side effects weren’t fully tracked, weight was only measured at doctor visits, and the patients may not represent everyone7

Which medicine has fewer side effects? 

Both medicines can cause stomach problems, gallbladder issues, and rare serious risks, but Wegovy is linked to fewer immune reactions and injection site problems than Zepbound. The decision must be made after thorough counselling with a doctor5,6

Can both drugs be taken long-term? 

Yes, both drugs can be taken long-term. Studies have shown sustained weight management and metabolic benefits over years with an acceptable safety profile. However, ongoing monitoring by a doctor is important to manage side effects and ensure continued safety14,15

Are Wegovy and Zepbound the same ingredients? 

No, Wegovy and Zepbound do not have same ingredients. Wegovy’s active ingredient is semaglutide, while Zepbound’s active ingredient is tirzepatide. The mechanisms of action of both medicines overlap but they are not identical3,4

References

  1. Qi QYD, Cox A, McNeil S, Sumithran P. Obesity medications: A narrative review of current and emerging agents. OsteoarthrCartil Open. 2024;6(2):100472. Published 2024 Apr 25. doi:10.1016/j.ocarto.2024.100472. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11088184/ 
  2. Singh G, Krauthamer M, Bjalme-Evans M. Wegovy (semaglutide): a new weight loss drug for chronic weight management. J Investig Med. 2022;70(1):5-13. doi:10.1136/jim-2021-001952. Available from:https://pmc.ncbi.nlm.nih.gov/articles/PMC8717485/ 
  3. Farzam K, Patel P. Tirzepatide. [Updated 2024 Feb 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK585056/ 
  4. Kommu S, Whitfield P. Semaglutide. [Updated 2024 Feb 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK603723/ 
  5. Novo Nordisk. Wegovy (semaglutide) injection, for subcutaneous use: U.S. prescribing information. U.S. Food and Drug Administration, Center for Drug Evaluation and Research; Revised June 2021. Application No. 215256. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215256s024lbl.pdf 
  6. Eli Lilly and Company. Zepbound (tirzepatide) injection, for subcutaneous use: U.S. prescribing information. U.S. Food and Drug Administration, Center for Drug Evaluation and Research; November 2023. Application No. 217806. Available from:https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/217806Orig1s020lbl.pdf 
  7. Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064. doi:10.1001/jamainternmed.2024.2525. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11231910/ 
  8. Gorgojo-Martínez JJ, Mezquita-Raya P, Carretero-Gómez J, et al. Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Glp-1 Receptor Agonists: A Multidisciplinary Expert Consensus. J Clin Med. 2022;12(1):145. Published 2022 Dec 24. doi:10.3390/jcm12010145. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9821052/ 
  9. Malhotra A, Grunstein RR, Fietze I, et al. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med. 2024;391(13):1193-1205. doi:10.1056/NEJMoa2404881. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11168245/ 
  10. Sara Sokary, Hiba Bawadi, The promise of tirzepatide: A narrative review of metabolic benefits, Primary Care Diabetes,Volume 19, Issue 3,2025,Pages 229-237,ISSN 1751-9918, Available from: https://www.primary-care-diabetes.com/article/S1751-9918(25)00081-6/fulltext 
  11. Semaglutide for cardiovascular risk reduction in people who are overweight or have obesity without diabetes (new indication). AustPrescr. 2025;48(3):107-108. doi:10.18773/austprescr.2025.024. Available from:https://pmc.ncbi.nlm.nih.gov/articles/PMC12187477/ 
  12. Jabbour S, Paik JS, Aleppo G, Sharma P, Gomez Valderas E, Benneyworth BD. Switching to Tirzepatide 5 mg From Glucagon-Like Peptide-1 Receptor Agonists: Clinical Expectations in the First 12 Weeks of Treatment. EndocrPract. 2024;30(8):701-709. doi:10.1016/j.eprac.2024.05.005. Available from:https://www.endocrinepractice.org/article/S1530-891X(24)00515-9/fulltext 
  13. Almandoz JP, Lingvay I, Morales J, Campos C. Switching Between Glucagon-Like Peptide-1 Receptor Agonists: Rationale and Practical Guidance. Clin Diabetes. 2020;38(4):390-402. doi:10.2337/cd19-0100. Available from:https://pmc.ncbi.nlm.nih.gov/articles/PMC7566932/ 
  14. Ryan, D.H., Lingvay, I., Deanfield, J. et al. Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial. Nat Med 30, 2049–2057 (2024). https://doi.org/10.1038/s41591-024-02996-7.  
  15. Qin W, Yang J, Ni Y, et al. Efficacy and safety of once-weekly tirzepatide for weight management compared to placebo: An updated systematic review and meta-analysis including the latest SURMOUNT-2 trial. Endocrine. 2024;86(1):70-84. doi:10.1007/s12020-024-03896-zAvailable from:https://pmc.ncbi.nlm.nih.gov/articles/PMC11445313/ 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Wegovy vs Ozempic: Differences, Uses, Dosage, Side Effects and More!  

Introduction

Are you wondering about the Ozempic vs Wegovy difference? While they both contain the same ingredient (semaglutide), these two drugs have been prescribed by doctors for different uses. 

Ozempic may be prescribed by your doctor to aid in management of Type 2 diabetes mellitus while Wegovy may be prescribed to help with weight management1,2

In this blog, we will explore the uses, dosing, side effects, mechanism, cost and the results of Ozempic vs Wegovy. 

Wegovy vs Ozempic Overview

Wegovy and Ozempic have gained immense popularity over the years. Though both contain the same key ingredient, semaglutide, they have been approved and marketed under separate brand names for different purposes. Ozempic was developed first with the goal of management of type 2 diabetes mellitus while Wegovy was developed to help in weight management1,2,3

This table shows the Wegovy vs Ozempic comparison to understand the key differences in the uses and doses available1,2

 Ozempic Wegovy 
Approval Year 20173 20213 
Key Ingredient Semaglutide Semaglutide 
Primary Use Management of Type 2 diabetes mellitus and may help to reduce the risk of heart diseases in these individuals. Chronic weight management in individuals who are obese or overweight and suffer from any weight related comorbidity such as type 2 diabetes mellitus, hypertension, etc4
Doses and Forms Available 0.25 mg, 0.5 mg, 1 mg, 2 mg Available as pre-filled injection pen with multiple doses. 0.25 mg, 0.5 mg, 1 mg, 1.74 mg, 2.4 mg Available as pre-filled injection for single use only. 

Wegovy vs Ozempic Uses

Semaglutide, a glucagon-like peptide-1 (GLP1) receptor agonist, is approved by the FDA as 2 separate medications – Wegovy and Ozempic5

Wegovy has been approved by FDA along with strict diet and physical activity mainly for chronic weight management in1,5

Ozempic has been approved by FDA mainly for2,5

However, it is also prescribed off-label for weight management. 

While their indications differ, both medications may improve metabolic health and may help in weight management as well. Because they contain the same active ingredient, both these medications share many benefits, such as reducing insulin resistance, lowering inflammation, and potentially decreasing the risk of complications related to obesity and cardiovascular disease1,2,5

Wegovy vs Ozempic Dosage and Dosing

Both Wegovy and Ozempic are generally administered as subcutaneous injections or as advised by your doctor. However, their approved uses, dose escalation schedules, and maximum doses differ. 

Both medications are generally injected subcutaneously into the abdomen, thigh, or upper arm or as advised by your doctor. Your doctor will recommend that you take the medication once weekly, preferably at the same time each week1,2.  

When we consider the Wegovy vs Ozempic dose, Wegovy is available in 5 different pens containing the prescribed doses of semaglutide (0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2 mg)1,6. Ozempic is available in pre-filled pen semaglutide dosages of 0.25 mg (for initiating treatment and not for sugar control), 0.5 mg, 1 mg, 2 mg.  

The differences in the Wegovy vs Ozempic dose in adults is as follows1,2

 Starting Dose Maximum Dose Maintenance 
Wegovy 0.25 mg / week 2.4 mg / week 1.7 mg or 2.4 mg / week 
Ozempic 0.25 mg / week 2 mg / week 0.5 mg or 1 mg or 2 mg / week 

If a dose of either of the medication is missed, it can be taken within 5 days. If beyond 5 days, the missed dose can be skipped. It’s ideal to consult the doctor for best advice on skipped dosages of medicines1,2

Semaglutide injection must always be used as directed and at the dose recommended by doctor.    

Wegovy vs Ozempic Side Effects

Side effects of both Wegovy and Ozempic are usually similar.  

Common ones include7

Serious side effects may include7,8

If you face any of these symptoms, it is important to consult your doctor and seek immediate medical care. 

Wegovy vs Ozempic: Results and Effectiveness

Both Wegovy and Ozempic contain the same active drug semaglutide. Semaglutide has been extensively studied in individuals with type 2 diabetes and obesity. It has shown significant reductions in HbA1c levels in several studies. In the SUSTAIN clinical trial program, the average HbA1c reductions ranged from 1.45% to 1.55%, depending on the dose (0.5 mg to 1 mg weekly). The trial also demonstrated its benefit for weight loss5,9.  

Another study, the STEP trial, established the effectiveness of semaglutide for weight loss at a dose of 2.5mg with a mean reduction in body weight by about 15% after 68 weeks10. Moreover, these trials also showed improvements in cardiometabolic health, including reductions in waist circumference, blood pressure, and lipid levels. 

When comparing Wegovy vs Ozempic for weight loss, there are no studies directly assessing the same. Although, a metanalysis of latest weight loss drugs showed that individuals who took 2.4 mg of semaglutide lost more weight than those who took 1 mg of semaglutide11, which is the usual maintenance dose of Wegovy.  

Thus, it can be summarized that the effects of Ozempic and Wegovy overlap. Both of these can lower blood sugar, manage weight, and improve cardiovascular outcomes, though the degree of benefit varies with the dose and target population. Generally, Ozempic is primarily chosen for patients with type 2 diabetes where glucose control is central, while Wegovy is the primary choice in obese or overweight individuals seeking chronic weight loss. 

Wegovy vs Ozempic Cost and Availability in India

When we look at the Ozempic vs Wegovy cost in the U.S., Ozempic, primarily indicated for type 2 diabetes, costs around $936/month, while Wegovy, primarily indicated for chronic weight management, is priced at $1,349/month. However, these medications are much cheaper in Europe, these drugs are significantly cheaper. Their high cost and effectiveness have kept them in global headlines12

Until recently, Wegovy was not available in India, though oral semaglutide (Rybelsus) was being used for management of diabetes. However, in June 2025, Novo Nordisk officially launched Wegovy in India as a once-weekly injectable for weight loss. Ozempic is still not approved in India, though the semaglutide molecule is available in oral form13. 

Wegovy in India is priced from ₹17,345 to ₹26,015/month depending on the dose you require13.  This is lower than global prices but still high for most patients. Moreover, most Indian health insurance policies do not cover weight management medications unless they are prescribed for conditions like type 2 diabetes. Hence, you should expect out-of-pocket expenses for Wegovy. Global demand for GLP‑1 medications has led to supply shortages, affecting availability in India too14

Wegovy vs Ozempic Ingredients and Mechanism

In Ozempic vs Wegovy ingredients, both medications share the same primary ingredient, semaglutide, however, the excipients may differ. In Wegovy, phenol content is not used as inactive ingredients which is present in Ozempic. 

Both medications act through the same mechanism, as they belong to the class known as GLP-1 receptor agonists. GLP-1 is a natural hormone in the body that helps regulate blood sugar and appetite. Semaglutide mimics the action of this hormone. By slowing down the emptying of food from the stomach, semaglutide makes you feel full for longer, which helps reduce food intake. At the same time, it improves how the body responds to insulin, keeping blood sugar levels more stable5,7

Precautions and Safety Considerations

Before starting Wegovy or Ozempic, a doctor must always be consulted. Any relevant medical and family history and the current health status should be disclosed to ensure safe and effective use. The following should be discussed with a doctor before using semaglutide7

Wegovy and Ozempic may also react with certain medications such as5

Always follow your doctor’s instructions closely as regular communication with your doctor helps reduce risks and ensures the best results. 

Switching Between Wegovy and Ozempic

Though both medications contain the same active ingredient semaglutide, they are prescribed for different purposes. While Wegovy is indicated for chronic weight management with or without diabetes, Ozempic is primarily approved for managing type 2 diabetes1,2. As the results may take time to show, its best to continue with the one prescribed by your doctor based on your needs. 

However, you may sometimes need to switch medications due to supply shortages, insurance coverage issues, or access limitations that make one medication more available than the other. In such cases, it is important to consult your doctor. Although Wegovy and Ozempic share the same active ingredient, their dosing schedules and maximum dosages differ. Hence, it is always recommended that you consult your doctor to understand the dosing equivalence of new medication for best results1,2.  

Moreover, self-switching or overlapping treatments can lead to serious side effects or reduced effectiveness. Therefore, always follow your doctor’s instructions and take the medicine as prescribed1,2

Conclusion

Wegovy and Ozempic are both semaglutide-based medications but are prescribed for different purposes. Wegovy is mainly prescribed for chronic weight management, while Ozempic is mainly prescribed for the management of type 2 diabetes mellitus.  

Though both medications contain the same ingredient, their dosing, approvals, and availability differ, making medical guidance essential when choosing or switching between them. If you are considering either medication, always consult your doctor to ensure the safest and most effective option for your health needs. 

Frequently Asked Questions (FAQs)

Are Wegovy and Ozempic the same? 

Wegovy and Ozempic are prescription medications both containing the same active ingredient semaglutide, however, their inactive ingredients can vary. Although both medications are FDA-approved, Wegovy is approved mainly for chronic weight management, while Ozempic is indicated for blood sugar control in type 2 diabetes1,2.  

Can I use Ozempic for weight loss? 

Ozempic which contains semaglutide, a GLP1 receptor agonist, can lead to weight loss when used off-label. However, it should not be used to manage weight loss alone as it is FDA-approved for the management of type 2 diabetes mellitus. It is important to consult your doctor and take this medication as directed1,2,12

Is Wegovy stronger than Ozempic?

Both medicines contain semaglutide but are approved for different purposes. While the maintenance dose of Wegovy is usually higher than Ozempic, it is primarily for weight management, while Ozempic is for diabetes. Consult your doctor to understand which medication will be most suitable for you1,2

Which has more side effects?

Though both medications can show adverse effects, studies have shown that the risk of gastrointestinal side effects such as nausea and vomiting increases with higher doses of semaglutide. Hence, if you are taking any of these medications and facing any side effects, it is best to consult your doctor as these side effects can be managed by gradually adjusting the dose of your medication15

How long do Wegovy and Ozempic take to show results?

Results vary by individual. Some people may notice appetite or blood sugar changes within weeks, while meaningful weight loss or glucose control usually takes several months of consistent use of semaglutide injections1,2

References

  1. FDA label. WEGOVY (semaglutide) injection, for subcutaneous use [Internet]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215256s007lbl.pdf 
  2. FDA label. OZEMPIC (semaglutide) injection, for subcutaneous use [Internet]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/209637s020s021lbl.pdf 
  3. Ryan N, Savulescu J. The Ethics of Ozempic and Wegovy. Journal of Medical Ethics [Internet]. 2025 Jan 23;jme-2024-110374. Available from: https://jme.bmj.com/content/medethics/early/2025/01/23/jme-2024-110374.full.pdf 
  4. DHSC Media Team. Accessing Wegovy for weight loss: Everything you need to know – Department of Health and Social Care Media Centre [Internet]. healthmedia.blog.gov.uk. 2023. Available from: https://healthmedia.blog.gov.uk/2023/09/04/accessing-wegovy-for-weight-loss-everything-you-need-to-know/ 
  5. Kommu S, Whitfield P. Semaglutide [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK603723/ 
  6. European Medicines Agency. ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS [Internet]. Available from: https://www.ema.europa.eu/en/documents/product-information/wegovy-epar-product-information_en.pdf 
  7. MedlinePlus. Semaglutide injection: MedlinePlus drug information [Internet]. medlineplus.gov. 2022. Available from: https://medlineplus.gov/druginfo/meds/a618008.html 
  8. Pillarisetti L, K. Agrawal D. Semaglutide: Double-edged Sword with Risks and Benefits. Archives of Internal Medicine Research [Internet]. 2025;8(1). Available from: https://fortuneonline.org/articles/semaglutide-doubleedged-sword-with-risks-and-benefits.pdf 
  9. Sorli C, Harashima SI, Tsoukas GM, Unger J, Karsbøl JD, Hansen T, Bain SC. Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial. Lancet Diabetes Endocrinol. 2017 Apr;5(4):251-260. Available from: https://pubmed.ncbi.nlm.nih.gov/28110911/
  10. Xie Z, Yang S, Deng W, Li J, Chen J. Efficacy and Safety of Liraglutide and Semaglutide on Weight Loss in People with Obesity or Overweight: A Systematic Review. Clin Epidemiol. 2022;14:1463-1476. Available from: https://www.dovepress.com/efficacy-and-safety-of-liraglutide-and-semaglutide-on-weight-loss-in-p-peer-reviewed-fulltext-article-CLEP  
  11. Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jódar E, Leiter LA, et al. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine [Internet]. 2016 Nov 10;375(19):1834–44. Available from: https://pubmed.ncbi.nlm.nih.gov/27633186/ 
  12. NEWS: Chairman Sanders Launches Investigation into Outrageously High Price of Ozempic and Wegovy in the United States» Senator Bernie Sanders [Internet]. Senator Bernie Sanders. Available from: https://www.sanders.senate.gov/press-releases/news-chairman-sanders-launches-investigation-into-outrageously-high-price-of-ozempic-and-wegovy-in-the-united-states/ 
  13. TOI Lifestyle Desk. Novo Nordisk’s Wegovy debuts in India: How it works, who it’s for, and how much it costs [Internet]. The Times of India. 2025 [cited 2025 Sep 3].  Available from: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/novo-nordisks-wegovy-debuts-in-india-how-it-works-who-its-for-and-how-much-it-costs/articleshow/122054770.cms 
  14. Chakrabarti SK, Chattopadhyay D. The Impact of Weight Loss Drugs on Health and Society in India. 2025 Jan 9;4(1):1–8.  Available from: https://www.researchgate.net/profile/Swarup-Chakrabarti/publication/387837332 
  15. Petri KCC, Ingwersen SH, Flint A, Zacho J, Overgaard RV. Exposure-response analysis for evaluation of semaglutide dose levels in type 2 diabetes. Diabetes, Obesity and Metabolism [Internet]. 2018 Jun 15 [cited 2021 Oct 22];20(9):2238–45.  Available from: https://pubmed.ncbi.nlm.nih.gov/29748996/ 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Adult Diaper Rash: Causes, Symptoms, Treatment & Home Remedies

Introduction

Diaper rash is not just a concern for babies. It can occur in adults too, and can be just as uncomfortable and frustrating. Adult diaper rash can occur due to several reasons such as incontinence (loss of urine or stool control), high moisture, or irritation to chemicals, and can get superimposed fungal (Candida albicans) or bacterial infections1.  

Adult diaper rash is common, however, it is completely manageable with proper hygiene practices, topical creams, and antifungal or antibacterial treatment, though severe or chronic rashes may require medical attention1. In this article, we will explore the causes, symptoms, effective treatments, and easy home remedies that may help to soothe the skin and prevent further rashes. 

What is an Adult Diaper Rash?

Adult diaper rash (or irritant contact dermatitis), is a simple term used for inflammation of skin that develops in areas covered by diapers, pads or incontinence briefs. While there can be a combination of factors causing this condition, it most commonly occurs when your skin is exposed to prolonged moisture due to contact with stool or urine for a long period of time (thus considered as a form of incontinence-associated dermatitis). This may lead to redness (erythema), maceration, soreness, itchiness, and erosion on your skin2. However, if you notice papules (bumps) or pustules (pus-filled boils) on your skin along with erythema and erosion, it may suggest a secondary fungal or bacterial infection which occurs as a complication to adult diaper rash2,3

Studies4 have shown that approximately 50% of adults with faecal or both (faecal and urinary incontinence) show diaper rash within two weeks. 

Causes of Adult Diaper Rash

Are you wondering what causes diaper rash in adults? In adults what is commonly called diaper rash often represents irritant or allergic contact dermatitis. It mostly occurs in individuals with incontinence due to excessive contact of skin with urine or stool, causing breakdown of skin barrier from prolonged moisture contact or pH disruption of skin, leading to inflammation. Other contributing factors include1,2,5

By understanding the common causes of diaper rash, you can take preventive steps and choose the right care to keep your skin healthy and comfortable1,5

Symptoms of Adult Diaper Rash

Diaper rash adult symptoms include1,5,7

Recognising these symptoms early can help prevent the rash from worsening and ensure timely treatment. 

Treatment for Adult Diaper Rash

To treat diaper rash effectively, you can follow these simple home remedies for diaper rash in adults which can be remembered with the pneumonic “ABCDE”8,9

1. Air

air

The area of your skin should be exposed to air as much as possible. Removing your diaper may minimise the friction and contact with moisture. 

2. Barrier

topical cream

Application of creams that contain zinc oxide or petroleum may help to create a barrier between your skin and the diaper, serving as a protective layer and reducing contact with urine and stool. 

3. Cleansing

employing safer hygiene practices

The skin in contact with the diaper should be cleaned gently and thoroughly with water and gentle cleansers. 

4. Dry Diaper

dry diaper

You should change your diaper frequently or as soon as it is soiled. This reduces the moisture on the skin which can lead to a diaper rash. Moreover, studies have shown that individuals using disposable, breathable and absorbable diapers are found to have a lesser incidence of diaper rash compared to reusable cloth diapers8

5. Education

washing hand with soap

Diaper rash can be prevented by following simple diaper hygiene techniques such as washing your hands before and after every diaper change, using a soft cloth for cleaning, avoiding the use of irritants (such as fragrances or alcohol) in cleaning agents, use of proper fitting diapers, and monitoring for secondary infections. 

6. Medication

Antibiotics and antifungal medication may be prescribed by the doctor if infection is confirmed. Low potency topical corticosteroids (such as hydrocortisone 0.5%) may be considered in moderate to severe inflammation. Consult your doctor and use as directed with caution, especially if you have infected skin1

By following the simple ABCDE steps, you can effectively reduce the risk of adult diaper rash and maintain healthy, comfortable skin8,9

Treatment for Diaper Rash from a Yeast or Fungal Infection

Diaper rashes caused by yeast or fungal infection (commonly Candida) need special care as they may not improve with simple measures. The classical sign of fungal infection by Candida albicans is bright red erythema with satellite pustules. This helps to distinguish it from irritant dermatitis. Its treatment focuses on keeping the area clean, reducing moisture, and using antifungal medicines1

If your rash is severe, painful, or does not improve after a few days of antifungal application, your doctor may suggest oral antifungal medicines if needed to help relieve your symptoms1

Complications of Untreated Diaper Rash

An untreated diaper rash can lead to1,2,5,7

You are more likely to develop these complications if you have a weak immune system or if you suffer from any chronic health conditions1,5,7

How to Prevent Adult Diaper Rash

Simple tips that you can follow to reduce diaper rash adults symptoms include1,5,9

Always monitor your skin for signs of redness and irritation and seek medical advice early to prevent any further complications. 

Also Read: Top Balance Exercises for Seniors to Improve Stability

When to Seek Medical Help?

You should see a doctor if your rash is not showing any improvement with treatment after 2 to 3 days, or if your rash spreads to other regions of your body such as your arms, face, abdomen. If you develop a fever or notice any pimples, sores filled with pus or large bumps, it is best to consult your doctor and seek prompt medical care for your condition5.  

Also Read: UTI in the Elderly: Symptoms, Causes, Treatment, and Prevention

Conclusion

Adult diaper rash is a common yet manageable problem that can cause discomfort and irritation, if it is not treated in time. By recognizing the early signs, practicing good hygiene, and following simple care practices such as the “ABCDE” approach, you may effectively manage and reduce the risk of rashes. 

In most cases, these steps are sufficient to relieve symptoms, but if the rash becomes severe, spreads to other areas, or does not improve within a few days, it is important to seek medical advice. Timely medical advice ensures proper treatment and prevents complications, keeping your skin healthy and comfortable.

Frequently Asked Questions (FAQs)

Does prolonged use of antibiotics increase the risk of diaper rash? 

Yes, taking antibiotics for a prolonged period of time can disrupt your normal skin and gut flora, thereby increasing your chances of developing fungal infections (such as Candida) that cause rashes.  If you are on antibiotics and notice a rash developing, it is important to consult your doctor so that antifungal treatment can be considered10

Can stress or anxiety worsen diaper rash? 

Stress does not directly cause diaper rash, but it can weaken your immune system and slow down healing. People under stress may also neglect proper hygiene or diaper care, which increases the risk of your rash worsening. Managing stress through relaxation techniques, exercise, or adequate rest can indirectly help the rash heal faster11

Are there specific clothes to avoid when experiencing a diaper rash? 

Yes. Tight or synthetic fabrics such as nylon and polyester should be avoided as they tend to trap heat and moisture against the skin, which can worsen irritation. Loose-fitting, breathable clothing material is recommended as it allows air circulation and helps keep the diaper area dry, reducing friction and discomfort5

Is adult diaper rash contagious? 

The rash itself is not contagious, so it cannot spread from one person to another just by touch. However, if the rash is caused by a fungal infection (like Candida) or bacteria, those organisms may spread in shared environments or through improper hygiene. Good handwashing and proper diaper disposal reduce this risk12

References

  1. Benitez A, Mendez MD. Diaper Dermatitis [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559067/ 
  2. Connolly M. Incontinence Associated Dermatitis (IAD) – Best Practice Principles [Internet]. 2018. Available from: https://www.cec.health.nsw.gov.au/__data/assets/pdf_file/0015/424401/Incontinence-Associated-Dermatitis-IAD-Best-Practice-Principles.pdf 
  3. Talapko J, Juzbašić M, Matijević T, Pustijanac E, Bekić S, Kotris I, et al. Candida albicans—The Virulence Factors and Clinical Manifestations of Infection. Journal of Fungi [Internet]. 2021 Jan 22;7(2):79. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7912069/ 
  4. Bliss DZ, Funk T, Jacobson M, Savik K. Incidence and Characteristics of Incontinence-Associated Dermatitis in Community-Dwelling Persons With Fecal Incontinence. Journal of Wound, Ostomy and Continence Nursing [Internet]. 2015 [cited 2019 Apr 24];42(5):525–30. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5068913/ 
  5. Atherton DL. The aetiology and management of irritant diaper dermatitis. 2001 Dec 21;15(s1):1–4.  Available from: https://pubmed.ncbi.nlm.nih.gov/11720071/ 
  6. Baren JM, Goldman RD, Al E. Pediatric emergency medicine [Internet] – Irritant Diaper Dermatitis. Philadelphia: Saunders / Elsevier, Cop; 2008. Available from: https://www.sciencedirect.com/science/article/abs/pii/B9781416000877501276 
  7. Better Health VIC. Nappy rash [Internet]. Vic.gov.au. 2012. Available from: https://www.betterhealth.vic.gov.au/health/HealthyLiving/nappy-rash 
  8. Wesner E, Vassantachart JM, Jacob SE. Art of prevention: The importance of proper diapering practices. International Journal of Women’s Dermatology [Internet]. 2019 Sep;5(4):233–4. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6831759/ 
  9. American Academy of Dermatology Association. How to treat diaper rash [Internet]. www.aad.org. Available from: https://www.aad.org/public/everyday-care/itchy-skin/rash/treat-diaper-rash 
  10. Mohsen S, Dickinson JA, Ranjani Somayaji. Update on the adverse effects of antimicrobial therapies in community practice. Canadian Family Physician [Internet]. 2020 Sep;66(9):651. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7491661/ 
  11. Alotiby A. Immunology of Stress: A Review Article. Journal of Clinical Medicine [Internet]. 2024 Oct 25;13(21):6394–4. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11546738/ 
  12. MedlinePlus. Candida infection of the skin: MedlinePlus Medical Encyclopedia [Internet]. medlineplus.gov. Available from: https://medlineplus.gov/ency/article/000880.htm 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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What is Magnesium Glycinate? Benefits, Uses, Dosage & Side Effects 

Introduction

Magnesium is an important mineral that may help the body in several processes, including producing energy, helping muscles move, and supporting nerves to send signals. It also helps control blood sugar and blood pressure. Most of the magnesium is stored in bones and muscles, and only a small amount circulates in the blood. Low magnesium levels in blood can cause muscle cramps, weakness, poor nerve function, and even serious heart problem1,2.  

When magnesium levels drop, doctors may recommend the most suitable form of magnesium supplementation to meet individual needs. There are different types of magnesium supplements available, like magnesium oxide, citrate, chloride, lactate, and glycinate. Among these, magnesium glycinate is a well-absorbed form in which magnesium is bound to an amino acid called glycine. This combination not only improves absorption but also makes it gentler on the stomach, reducing the chance of digestive discomfort compared to other forms. Magnesium glycinate has been shown to be helpful for people experiencing stress, anxiety, sleep difficulties, or tiredness3,4

In this blog, we will explore magnesium glycinate benefits, uses, side effects, and foods containing magnesium glycinate. 

What Is Magnesium Glycinate?

Magnesium glycinate is a nutritional supplement that provides the body with magnesium. In this form, magnesium is joined with glycine, a small building block of protein. Together, they form a stable compound called a chelate4,5. This may help the body absorb magnesium better, giving it high bioavailability. Bioavailability means the amount of magnesium the body can actually use after taking it6

The amount absorbed may depend on many factors. Internal factors include age, overall health, and how much magnesium is already in the body. External factors include the dose, the type of food eaten with it, and the form of the supplement. Some suppliers of raw materials do not fully join magnesium with glycine. Instead, they may just mix magnesium carbonate or magnesium oxide with glycine and call it magnesium glycinate. This is only a dry mix of two separate compounds, with little or no actual bonding, so it is not the same as true magnesium glycinate. It is recommended to choose a high-quality, approved supplement with good formulation4,6.  

Next, we will look at the benefits of magnesium glycinate. 

Benefits of Magnesium Glycinate

Magnesium glycinate may be recommended when the body’s magnesium levels are low, or when magnesium from food is not enough5,7. It is considered useful for supporting various areas of health including: 

1. Brain and Nerve Health

brain

Magnesium supplementation may play an important role in calming certain brain switches called NMDA receptors, which may become overactive when magnesium levels are low. It may also help relax blood vessels and aid in circulation to support healthy brain and nerve function4,8

2. Blood Sugar and Energy

regulates blood sugar

Magnesium supplementation, along with zinc, selenium, vitamin C, and vitamin E, may show positive effects in regulating blood sugar. It may help improve insulin sensitivity, keeping fasting sugar levels under control. It may also help maintain healthy cholesterol levels in people with diabetes and heart disease. 

3. Improve Bone Health

strengthen bones

Magnesium is needed to convert vitamin D into its active form, helping the body absorb calcium and support parathyroid hormone activity. Supplementation with magnesium may contribute to bone health, especially when combined with vitamin D and calcium. It may also help lower bone turnover in elderly women after menopause. 

4. Heart Benefits

heart

Magnesium taken orally may act as a natural calcium channel blocker, which can help ease blood vessel tension, improve blood vessel function in the heart, and may even help control blood pressure in people with diabetes and heart disease. 

5. Improve Muscle Function

boost immune system

Magnesium may help in muscle contraction. When levels are low, magnesium deficiency can cause muscle cramps. By restoring magnesium levels, muscle function may improve3,7

6. Kidney Stone Prevention

kidney stone

Magnesium supplementation may reduce calcium oxalate crystal formation and decrease intestinal oxalate absorption, helping prevent kidney stone formation6

7. Mental Health and Sleep

sleep

Magnesium helps the body make serotonin, a chemical that affects mood and feelings of happiness. Magnesium supplementation may help calm the brain by slowing overactive signals and supporting relaxing signals (GABA agonist), which can make it easier to feel calm and sleep better, but these effects are not very strong or consistent3,7

8. Antioxidant and anti-inflammatory support

reduces inflammation

Magnesium glycinate may help protect the body from oxidative stress and help fight inflammation in the body owing to its antioxidant and anti-inflammatory properties3,8

An important benefit of magnesium glycinate is that it is a chelated form, where magnesium is bonded with glycine. It is well absorbed by the body, with some of it taken in as a small, complete unit called a dipeptide in the upper part of the small intestine. This special absorption makes it gentle on the stomach and an effective option compared to other types of magnesium supplements4,6

Note: While initial studies have shown benefits of magnesium supplementation, further large-scale human-trials are needed to confirm these.  

Magnesium Glycinate Uses

Magnesium glycinate may be used in the management of several health conditions including: 

Thus, magnesium glycinate may be useful inmanaging magnesium deficiency and related health issues, and next we will see how it compares with other types of magnesium in effectiveness, absorption, and tolerance. 

Magnesium Glycinate vs. Other Forms

Magnesium supplements come in many forms, mainly divided into two types: inorganic or organic. Inorganic forms, like magnesium oxide, may provide a high amount of magnesium but may not be absorbed well in the gut. Organic forms, like magnesium citrate, may dissolve more easily and may be absorbed better1.  

One important magnesium glycinate benefit is, it is one of the organic forms that is gentle on the gut and may usually cause fewer stomach issues or loose stools compared to some other forms. It has high bioavailability and is usually absorbed well in the gut14,15. Thus, it may be a suitable option for long-term use and for people with special needs, like after intestinal surgery (ileal resection), where absorption is affected13

Other forms of magnesium may vary in absorption and effects: 

Overall, magnesium glycinate may offer better absorption, higher bioavailability, and fewer digestive issues, and may be a well-tolerated choice compared to many other forms of magnesium. 

Signs of Magnesium Deficiency

Low magnesium may not always show clear signs, especially if the shortage is mild. However, when the deficiency becomes excessive, it may affect muscles, nerves, and the heart. 

People with conditions like diabetes may be more likely to have low magnesium, and long-term deficiency may increase the risk of heart problems6,7

Dosage: How Much Should You Take?

Magnesium glycinate may be prescribed in different amounts depending on the situation. The recommended dose is mostly 200- 400mg of elemental magnesium per day, sometimes given in divided doses. At higher doses, side effects like diarrhoea may occur4.  

The doctor may decide the exact dose based on your individual needs, condition, and health situation. 

Side Effects

Magnesium glycinate is generally well tolerated, and side effects are uncommon. Some people may notice mild stomach issues at high doses of supplements, which can sometimes cause loose stools, nausea, or abdominal cramps. Very high levels may rarely lead to more serious issues like low blood pressure, extreme tiredness, or irregular heartbeat3,7. Other effects like sleep changes, headaches, dizziness, increased thirst, frequent urination, or joint pain are very rare or unlikely14,17.  

When you experience these magnesium glycinate side effects, you need to pay attention and let your doctor know. Your doctor may adjust the dose or check for interactions with any medicines you are taking. The dose your doctor decides may depend on your health condition and what magnesium is prescribed for. 

Foods Rich in Magnesium

Foods do not naturally have magnesium glycinate, but many contain magnesium itself, which the body can use. Green leafy vegetables like spinach and kale, legumes such as beans and lentils, nuts including almonds and cashews, and seeds like pumpkin or chia are good sources. Whole grains, brown rice, soy products, and some dairy like milk and yogurt also provide magnesium. Certain breakfast cereals are fortified with magnesium to add extra amounts. 

The amount of magnesium in foods can vary depending on how they are processed. For example, refined grains lose magnesium when the nutrient-rich parts are removed. Water can also contain magnesium, though levels vary by source. Eating a mix of these foods helps the body get enough magnesium to support normal functions. 

Examples of magnesium-rich foods: spinach, kale, beans, lentils, almonds, cashews, pumpkin seeds, chia seeds, brown rice, oatmeal, milk, yoghurt, salmon, and avocado2,7

Conclusion

Magnesium glycinate may be a helpful option when your body needs extra magnesium or food alone is not enough to meet the needs. It may be absorbed well, is gentle on the stomach, and suitable for long-term use in healthy adults with normal kidney function, or for special needs, like after intestinal surgery. People with kidney problems should use it with caution and under monitoring. Other forms of magnesium may work differently in absorption and tolerance. Your doctor may decide if magnesium glycinate is right for you, and the exact dose will depend on your health and what it is prescribed for. 

Frequently Asked Questions (FAQs)

Which magnesium is best for high blood pressure?

Magnesium in forms like citrate, oxide, aspartate, and chloride are used to support healthy blood pressure. No single form is shown to be superior; dose and duration are more important. A daily intake of about 400-500 mg may be associated with blood pressure benefits. Among the types, magnesium citrate is absorbed well, oxide may sometimes upset the stomach, and magnesium glycinate is gentle and its use in high blood pressure is under research4,18

Is magnesium glycinate a sleeping pill?

Magnesium glycinate is not a sleeping pill. It may support relaxation and calm the nervous system, which can help with sleep in some people. Your doctor may decide if it is appropriate for your sleep needs3,7.  

Is magnesium glycinate good for migraines?

Magnesium glycinate may be used to reduce the frequency and severity of migraine headaches. It is well absorbed and gentle on digestion. Your doctor may advise if it is suitable for your situation and the correct dose4

What does magnesium glycinate do to the brain?

Magnesium glycinate may help regulate nerve signals in the brain, supporting calmness and normal function. It may help protect nerve cells and support overall brain activity4,8

What is the best time to take magnesium glycinate?


The best time to take magnesium glycinate depends on doctor guidance and the condition being treated. Some people may take it at different times, in divided doses, or after meals or at bedtime. Timing can vary and should follow individual recommendations16,18

References

  1. Blancquaert L, Vervaet C, Derave W. Predicting and Testing Bioavailability of Magnesium Supplements. Nutrients. 2019 Jul 20;11(7):1663. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6683096/  
  2. National Institutes of Health. Magnesium [Internet]. National Institutes of Health. 2022. Available from: https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/  
  3. Cepeda V, Ródenas-Munar M, García S, Bouzas C, Tur JA. Unlocking the Power of Magnesium: A Systematic Review and Meta-Analysis Regarding Its Role in Oxidative Stress and Inflammation. Antioxidants. 2025 Jun 16;14(6):740–0. Available from: https://www.mdpi.com/2076-3921/14/6/740 
  4. Magnesium Glycinate – an overview | ScienceDirect Topics [Internet]. www.sciencedirect.com. Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/magnesium-glycinate  
  5. PubChem. Magnesium glycinate [Internet]. pubchem.ncbi.nlm.nih.gov. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-glycinate  
  6. Pardo MR, Garicano Vilar E, San Mauro Martín I, Camina Martín MA. Bioavailability of magnesium food supplements: A systematic review. Nutrition (Burbank, Los Angeles County, Calif) [Internet]. 2021 Sep 1 [cited 2021 Nov 8]; 89:111294. Available from: https://pubmed.ncbi.nlm.nih.gov/34111673/  
  7. Schwalfenberg GK, Genuis SJ. The importance of magnesium in clinical healthcare. Scientifica. 2017 Sep 28;2017(1):1–14. Available from: https://onlinelibrary.wiley.com/doi/full/10.1155/2017/4179326  
  8. Magnesium Glycinate – an overview | ScienceDirect Topics [Internet]. www.sciencedirect.com. Available from: https://www.sciencedirect.com/topics/nursing-and-health-professions/magnesium-glycinate  
  9. Factors Group Australia Pty Ltd. Public Summary – ARTG Entry: 503930 Magnesium Glycinate [Internet]. TGA; 22 July 2025. Available from: https://www.ebs.tga.gov.au/servlet/xmlmillr6?dbid=ebs/PublicHTML/pdfStore.nsf&docid=503930&agid=%28PrintDetailsPublic%29&actionid=1 
  10. Abbasi B, Masud Kimiagar, Khosro Sadeghniiat, Shirazi MM, Hedayati M, Bahram Rashidkhani. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences [Internet]. 2012 Dec;17(12):1161. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC3703169/  
  11. Boyle N, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review. Nutrients. 2017 Apr 26;9(5):429. Available from: https://pubmed.ncbi.nlm.nih.gov/28445426/  
  12. Interventions for leg cramps during pregnancy | Cochrane [Internet]. Cochrane.org. 2020 [cited 2025 Sep 17]. Available from: https://www.cochrane.org/evidence/CD010655_interventions-leg-cramps-during-pregnancy  
  13. Schuette SA, Lashner BA, Janghorbani M. Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection. JPEN Journal of parenteral and enteral nutrition [Internet]. 1994;18(5):430–5. Available from: https://pubmed.ncbi.nlm.nih.gov/7815675/
  14. 101.Fatima G, Dzupina A, Alhmadi HB, Magomedova A, Siddiqui Z, Mehdi A, et al. Magnesium Matters: A Comprehensive Review of Its Vital Role in Health and Diseases. Cureus [Internet]. 2024 Oct 13;16(10). Available from: https://www.cureus.com/articles/300811-magnesium-matters-a-comprehensive-review-of-its-vital-role-in-health-and-diseases# 
  15. 102.Aniebo Umoh E, Obembe AO, Ikpi DE, Ekpenyong Eniang-Esien O, Okon Asuquo J, Effiom-Ekaha OO. Effect of chronic administration of magnesium supplement (magnesium glycinate) on male albino wistar rats’ intestinal (Ileum) motility, body weight changes, food and water intake. Heliyon [Internet]. 2023 Aug 1;9(8):e19042. Available from: https://pubmed.ncbi.nlm.nih.gov/37636381/ 
  16. 103.Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Medical Hypotheses [Internet]. 2006 Jan;67(2):362–70. Available from: https://pubmed.ncbi.nlm.nih.gov/16542786/ 
  17. 104.Schuster J, Igor Cycelskij, Lopresti A, Hahn A. Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial. Nature and Science of Sleep [Internet]. 2025 Aug 1 [cited 2025 Sep 17];Volume 17:2027–40. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC12412596/ 
  18. ClinicalTrials.gov. Magnesium Supplementation and Blood Pressure Reduction. Study record for NCT03688503 [Internet]. Bethesda (MD): National Library of Medicine (US); 2018 Nov 16 [cited 2025 Sep 17]. Available from: https://clinicaltrials.gov/study/NCT03688503   

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Flu Shot Side Effects: Duration, Common Reactions & Ways to Feel Better

Introduction

Flu or influenza is an infection caused by influenza viruses, typically the A, and B types. Influenza spreads easily and can affect people of any age, from children to the elderly1,2.  While most of them recover within a few days, uncomplicated flu takes about 5–7 days to resolve, and tiredness or cough can last up to 2 weeks3

Sometimes flu can lead to serious problems like pneumonia (directly caused by the flu, or by superimposed bacterial infection) and worsening of diseases like asthma, diabetes, and heart problems. Every year, millions of people get affected by flu worldwide, with many even needing hospital admission. Taking a flu shot is the most effective way to lower this risk. It not only helps prevent flu infection but also reduces the risk of complications and hospitalisation4,5

While the benefits of the flu shot are clear, some people worry about what happens after the flu shot and whether they will get side effects. Like any vaccine, the flu shot may cause some side effects, but they are mostly mild and short-term6. In this blog, let’s see what the flu shot side effects are, how long they last, and simple ways to feel better.  

Types of Flu Vaccines

There are three main types of influenza vaccines: the inactivated influenza vaccine, the live attenuated influenza vaccine and the recombinant influenza vaccine (RIV). The inactivated vaccine contains killed viruses and is given as an injection. The live attenuated vaccine is made from weakened viruses and is available as a nasal spray1,7. Recombinant vaccines, such as FluBlok, are newer vaccines made without using the flu virus or eggs, especially for people with egg allergies. These are available in some countries but are not common in India.  

In India, the commonly used form is the inactivated influenza vaccine, which is administered as an injection into the arm muscle in adults, and into the thigh muscle in infants1,7. It is recommended for people at higher risk, such as children aged six months and older, adults over 65 years, pregnant women, healthcare workers, and people with chronic illnesses like asthma, diabetes, or heart disease1. It is not recommended for all adults, unlike in some countries such as the US, where vaccination is advised for everyone4

How to Prepare for the Flu Shot?

When you get the flu shot, your body’s immune system is activated to produce protective antibodies against the flu virus. The antibodies are developed within 2 weeks after you get your flu shot. These antibodies are mainly responsible for the effectiveness of vaccines and protect children and adults from severe infection. When you get infected with flu, your body also produces antibodies, but this protection works only against the same type of flu and slowly fades away, especially because the flu virus keeps changing its form. In the same way, the antibodies produced by the vaccine gradually decline over time4,9. Therefore, it is recommended to get your flu shot yearly once before the flu season to protect yourself.  

You can prepare yourself by following these simple things before you get a flu shot: 

What to Expect After Getting the Flu Shot?

After getting the flu shot, it’s normal to experience mild soreness, pain, swelling or redness at the site of injection. Small children may become irritable and cry excessively. These signs are generally nothing to worry about and resolve soon on their own4,6.  

Some individuals, especially adolescents, may have a fainting sensation during or after the vaccination, but this is mainly due to anxiety related to the injection process and not the side effects of injection per se. If you feel dizzy, you will be made to sit for 15-20 mins and monitored after the injection11

There are some other minor or rarely major side effects that may occur after getting the flu shot. We’ll discuss these in detail in the following sections. 

Most Common Side Effects

Flu shots are generally safe, but mild flu vaccine side effects may be seen. 

Serious Side Effects

Serious flu shot side effects are very rare. Only 1 to 2 people out of 1 million doses may have a severe allergic reaction seen as: 

These reactions can sometimes start even after leaving the clinic or hospital15,16

In very rare cases, some people may have a risk of developing flu vaccine long-term side effects like Guillain-Barré syndrome (GBS) a few days or weeks after vaccination. GBS is a rare disorder where the immune system attacks the nerves, causing weakness and, in some cases, paralysis. However, the chance of getting GBS from the flu vaccine is extremely rare, about 1 to 2 people in every 1 million. This risk is much lower than getting GBS from catching the flu itself17

Can You Get the Flu from the Flu Shot?

Flu vaccines are made with viruses that are no longer active or with particles that mimic the flu virus, so they cannot cause flu directly. Instead, they help your body build an immune response and produce antibodies against flu6,9

Sometimes, a person may still get flu after being vaccinated, but this is not because of the vaccine. It could happen if you are exposed to flu within 1–2 weeks after the shot, before your body develops full protection, or if you catch a flu strain not covered by the vaccine. 

The nasal spray flu vaccine (not available in India) contains a weakened form of the virus. In rare cases, it may cause mild cold-like symptoms, but not true flu. This is not seen in other types of flu vaccines4,7

In fact, it helps protect you and usually makes illness milder if you do get infected. Vaccinated people have a much lower risk of hospitalisation and death from flu. 

Other reasons someone might get flu after vaccination include catching it before the body has finished building protection, facing a flu strain not covered by the vaccine, or the vaccine’s effect wearing off later in the season4,9

How Long Do Side Effects Last?

Most flu shot side effects are mild, like pain at the injection site, headache, tiredness, and muscle pain, usually go away within 1 to 3 days. In some cases, soreness or swelling at the injection site may last up to 7 days14

Some may develop mild allergic skin reactions, like hives, which settle within 24 hours. Rarely, delayed reactions like skin rashes are seen which may occur hours to several days after receiving the flu shot18

Serious allergic reactions, such as angioedema (swelling of the face, lips, or throat) or anaphylaxis, occur within minutes to a few hours, but are very rare. With proper treatment, symptoms usually resolve within hours if not severe19,20

Guillain-Barré Syndrome (GBS) is an extremely rare flu vaccine long-term side effect that may occur 2 to 6 weeks after vaccination. Recovery may take months to years, depending on severity21,22. 

Managing Flu Shot Side Effects

The flu vaccine side effects can be managed by doing these simple things at home: 

Should You Get the Flu Shot Even with Possible Side Effects?

The flu vaccine may cause mild side effects, but these are very minor compared with the benefits. It protects against influenza virus infection and greatly lowers the risk of serious illness. While no vaccine gives 100% protection, people who get the flu after vaccination are far less likely to experience severe complications, hospitalizations and even prevents ICU admissions. This protection is especially important for high-risk groups such as children, pregnant women, older adults, and people with chronic conditions. Even if you get the flu after vaccination, it is usually milder when compared with those who are not vaccinated. This makes it important to get your yearly flu shot26,27

When to Talk to Your Doctor

You should see a doctor after a flu shot if pain or fever is not relieved by paracetamol, or if symptoms are severe, worsening, persistent, or causing concern. Seek medical advice if these symptoms last more than seven days. Seek urgent care immediately if you experience flu vaccine side effects like severe allergic reactions, including difficulty breathing, swelling of the face or throat, a rapid heartbeat, widespread rash, dizziness, or weakness16,25

Conclusion

Flu shots are safe and effective, with side effects that are usually mild and short-term. They protect against flu infection, reduce the risk of complications, hospitalizations, and ICU admissions, and also protect high-risk groups such as children, pregnant women, older adults, and those with other long-term health conditions. Getting a flu vaccine every year can protect you and those around you, helping keep the community healthy throughout the flu season. 

Frequently Asked Questions (FAQs)

Can I receive a flu shot while I am pregnant?

Yes, you can get a flu shot during pregnancy. It helps protect you from getting the flu, reduces the risk of hospitalization, and passes antibodies to your baby before birth28

Are there special flu shots for older adults?


Yes, people over 60 can get stronger flu vaccines, such as the high-dose or adjuvanted flu vaccine, which boost the immune system and provide better protection than the regular flu shot. These vaccines also help reduce complications. 

Should I get the flu shot every year?

Yes, you need to get a flu shot every year because the influenza virus changes constantly. Annual vaccination prepares your body to fight the current type or strain of flu circulating that season. 

Is the flu shot just one injection?

For most adults, only one injection is needed. However, children aged 6 months to 9 years who are receiving the flu shot for the first time, and people who have undergone transplant or have special health conditions, may need two shots, spaced one month apart8.  

References

  1. Ministry of Health and Family Welfare; Directorate General of Health Services (Emergency Medical Relief). Seasonal Influenza: Guidelines for Vaccination with Influenza Vaccine [Internet]. Updated 25 April 2017. Available from: https://www.mohfw.gov.in/sites/default/files/Seasonal%20Influenza%20-%20Guidelines%20for%20vaccination%20with%20Influenza%20Vaccine%20%28updated%29.pdf  
  2. World. Influenza (Seasonal) [Internet]. Who.int. World Health Organization: WHO; 2023. Available from: https://www.who.int/news-room/fact-sheets/detail/influenza-%28seasonal%29  
  3. CDC. Clinical Signs and Symptoms of Influenza [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/hcp/clinical-signs/index.html  
  4. Centers for Disease Control and Prevention. Key Facts About Seasonal Flu Vaccine [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/vaccines/keyfacts.html  
  5. Rothberg MB, Haessler SD, Brown RB. Complications of Viral Influenza. The American Journal of Medicine. 2008 Apr;121(4):258–64. Available from: https://www.sciencedirect.com/science/article/pii/S0002934308000727  
  6. CDC. Flu Vaccine Safety [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/vaccine-safety/index.html 
  7. Types of seasonal influenza vaccine [Internet].. 2010. Available from: https://www.who.int/europe/news-room/fact-sheets/item/types-of-seasonal-influenza-vaccine 
  8. Australia H. Flu vaccine FAQs [Internet]. 2020. Available from: https://www.healthdirect.gov.au/flu-vaccine-faqs  
  9. Jones CH, Hauguel T, Beitelshees M, Davitt M, Welch V, Lindert K, et al. Deciphering immune responses: a comparative analysis of influenza vaccination platforms. Drug Discovery Today [Internet]. 2024 Sep [cited 2024 Oct 9];29(9):104125. Available from: https://www.sciencedirect.com/science/article/pii/S1359644624002502#f0025 
  10. CDC. Vaccine Administration: Before Giving Vaccine [Internet]. Vaccines & Immunizations. 2025. Available from: https://www.cdc.gov/vaccines/hcp/administration/before.html 
  11. CDC. Before, During, and After Shots [Internet]. Vaccines for Your Children. 2024. Available from: https://www.cdc.gov/vaccines-children/before-during-after-shots/index.html 
  12. Channels D. About your vaccination appointment [Internet]. NSW Government. 2021 [cited 2025 Aug 22]. Available from: https://www.nsw.gov.au/health/covid-19/vaccination/what-to-expect 
  13. CDC. Getting a Flu Vaccine and other Recommended Vaccines at the Same Time [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/vaccines/coadministration.html 
  14. Trombetta CM, Gianchecchi E, Montomoli E. Influenza vaccines: Evaluation of the safety profile. Human Vaccines & Immunotherapeutics [Internet]. 2018 Jan 30 [cited 2019 Oct 28];14(3):657–70. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861790/pdf/khvi-14-03-1423153.pdf 
  15. CDC. Inactivated Influenza Vaccine VIS [Internet]. Vaccines & Immunizations. 2024. Available from: https://www.cdc.gov/vaccines/hcp/current-vis/influenza-inactivated.html 
  16. U.S. Department of Health and Human Services. Vaccine side effects [Internet]. HHS.gov. 2021. Available from: https://www.hhs.gov/immunization/basics/safety/side-effects/index.html 
  17. CDC. Guillain-Barré Syndrome and Flu Vaccine [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/vaccine-safety/guillainbarre.html 
  18. McNeil MM, DeStefano F. Vaccine-associated hypersensitivity. Journal of Allergy and Clinical Immunology. 2018 Feb;141(2):463–72. Available from: Vaccine-associated hypersensitivity – PMC 
  19. Canada PHA of. Anaphylaxis and other Acute Reactions following Vaccination: Canadian Immunization Guide [Internet]. 2007. Available from: https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-2-vaccine-safety/page-4-early-vaccine-reactions-including-anaphylaxis.html 
  20. CDC. Preventing and Managing Adverse Reactions [Internet]. Vaccines & Immunizations. 2024. Available from: https://www.cdc.gov/vaccines/hcp/imz-best-practices/preventing-managing-adverse-reactions.html 
  21. Nizar Souayah, Yacoub HA, Khan HMR, Farhad K, Lubna Shafiq Mehyar, Maybodi L, et al. Guillain–Barré Syndrome After Influenza Vaccination in the United States, A Report From the CDC/FDA Vaccine Adverse Event Reporting System (1990–2009). Journal of Clinical Neuromuscular Disease. 2012 Nov 21;14(2):66–71. Available from: https://journals.lww.com/jcnmd/abstract/2012/12000/guillain_barr__syndrome_after_influenza.2.aspx 
  22. Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barré syndrome. Lancet. 2016 Aug 13;388(10045):717–27. Available from: https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0140673616003391?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0140673616003391%3Fshowall%3Dtrue&referrer=https:%2F%2Fpubmed.ncbi.nlm.nih.gov%2F  
  23. Immunization Action Coalition. After the shots…what to do if your child has discomfort. Item #P4015. St. Paul, MN: Immunization Action Coalition; 2023 Mar 29. Available from: https://www.immunize.org/wp-content/uploads/catg.d/p4015.pdf 
  24. CDC. Getting Your COVID-19 Vaccine [Internet]. COVID-19. 2024. Available from: https://www.cdc.gov/covid/vaccines/getting-your-covid-19-vaccine.html 
  25. What to do before, during and after getting vaccinated for COVID-19 [Internet]. Available from: https://www.unicef.org/rosa/stories/what-do-during-and-after-getting-vaccinated-covid-19 
  26. CDC. Factors Influencing Flu Vaccine Effectiveness [Internet]. Flu Vaccines Work. 2024. Available from: https://www.cdc.gov/flu-vaccines-work/how-well/index.html 
  27. Australian Government Department of Health and Aged Care. Table. Comparison of the effects of diseases and the side effects of vaccines on the National Immunisation Program [Internet]. The Australian Immunisation Handbook. 2021. Available from: https://immunisationhandbook.health.gov.au/resources/tables/table-comparison-of-the-effects-of-diseases-and-the-side-effects-of-vaccines-on-the-national-immunisation-program 
  28. CDC. Flu Vaccine Safety and Pregnancy [Internet]. Influenza (Flu). 2024. Available from: https://www.cdc.gov/flu/vaccine-safety/vaccine-pregnant.html 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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Falls in the Elderly: Life expectancy, Causes, Prevention, & Safety Tips 

Introduction

The World Health Organisation defines fall as “an event which results in a person coming to rest inadvertently on the ground or floor or other lower level.” About 684,000 falls are reported each year worldwide involving all ages1. However, accidental falls are more common in the elderly (over the age of 65 years). An estimated 30% of the elderly population have one or more falls each year, increasing up to 50% in adults over 80 years, worldwide2. By 2050, there are expected to be about 200 crore (2 billion) people over the age of 60 years worldwide. In India, the percentage of elderly people is estimated to be 12.4% of the entire population by the end of 20263. About 10 lakh (1 million) elderly people die in India annually, and almost twice as many are injured due to accidental falls. About 10% of the elderly experience recurrent falls4. This can lead to increased health care costs, especially out-of-pocket expenses. Accidental falls in the elderly are fast becoming a major health concern, leading to mental health issues in them and impacting their quality of life5. Fall prevention in the elderly and management of related injuries is a critical challenge for health care personnel globally. 

Who is at Most Risk?

Although anyone can fall anytime, certain groups of people are at a higher risk of experiencing a fall, such as: 

Causes of Falls in the Elderly

There is no one specific reason why the elderly fall. However, there are several factors which can increase the risk of falls and injury in the elderly. Some of these include: 

1. Extrinsic or environmental factors

2. Intrinsic or personalised factors

3. Factors involving special circumstances

Most falls are the result of a combination of one or more factors. 

Symptoms of Falls in the Elderly

Symptoms such as dizziness or light-headedness often precede some accidental falls. Many accidental falls may not cause major injuries. However, it is best to watch out for the following symptoms after a fall that may lead to serious complications: 

Contact your doctor immediately if you have any serious symptoms after a fall10,11

Diagnosis

There are no specific mandatory tests to be performed after a fall. However, doctors follow standard guidelines and may advise testing depending on the suspected cause of the fall, the type of injuries and your physical condition. These may include: 

Treatment of Falls in the Elderly

Treatment of falls in the elderly depends on the cause of the fall, the injuries caused by the fall and the physical condition. Broadly, they can be categorised as: 

Every treatment should be tailored to each case, specifically involving multiple specialists like doctors, nurses, physiotherapists, social and community workers, etc. It is best to discuss the treatment options with your doctor13,14

How to Prevent Falls in the Elderly?

Although it may not be realistically possible to prevent falls completely, steps may be taken to reduce the chances of falling and fall-related injury in elderly. Fall prevention in the elderly requires a multidimensional approach, for example: 

Besides medical or clinical interventions, lifestyle changes and exercise programs should be incorporated in routine. Environmental or home modifications may be required to make the surroundings safer13,15

Let’s have a look at these in detail in the next section. 

Lifestyle and Environmental Changes

Making the elderly feel safe and building their confidence is of prime importance. Adopting certain lifestyle changes and following some safety guidelines can help reduce the risk of accidental falls, such as:  

Emergency Response and Follow-up

If you are attending to someone who has had a fall, call for an ambulance or emergency services if: 

When to Seek Medical Help?

Many falls may cause only a slight injury or discomfort. However, if you do not recover from the mild symptoms within a couple of weeks, you should consult your doctor5,10. If you or someone around you is not feeling well or is uncomfortable after a fall, contact your doctor immediately.  Seek medical help if you experience worsening of symptoms or developing new serious symptoms like: 

Also Read: Pneumonia in the Elderly: Causes, Symptoms, Treatment, and Prevention 

Conclusion

Falls in elderly are common and can be dangerous. A single fall can lead to a domino effect of health issues ranging from minor injuries to prolonged hospitalisations, immobility, and loss of independence. Fortunately, avoiding a fall or reducing the chances of a fall is frequently possible with the certain proactive measures. Fall prevention in the elderly is achievable by adopting a multidimensional approach of early recognition and reduction of the risk factors, regular health check-ups, and making optimal lifestyle changes.  The responsibility of fall prevention is shared by health care professionals, family members, caregivers, the elderly themselves, and the wider community. Together, with a multidisciplinary, holistic approach, our elderly can not only avoid falls, but also enjoy a life of dignity, independence, and vitality that they deserve in their golden years. 

Also Read: Adult Diaper Rash: Causes, Symptoms, Treatment & Home Remedies

Frequently Asked Questions (FAQs)

How can I know my risk of falling? 

Doctors can assess your risk of falling with the help of STEADI (Stopping Elderly Accidents, Deaths, and Injuries) protocol, which is developed by the Centres for Disease Control and Prevention in three stages:
-Screening: A detailed history of previous falls, medical conditions, and problems with movement, like unsteadiness, imbalance, etc 
Assessment: Your doctor can perform a series of tests to assess your fall risk. Ask your doctor if you want to know more about them. 
Intervention: By helping you to make decisions on your health and implement strategies to reduce fall risk19

What types of injuries are common with falls in the elderly? 

Depending on the force of the fall and how you fall, different parts of the body may be involved, such as bones, joints, muscles, nerves, ligaments, tendons, and blood vessels. A fall can cause fractures of the bones or inside the joints, dislocations, sprains, muscle pulls, nerve damage, cuts, and bruises3,15.  

How long does it take to recover from a fall? 

The recovery process is slow in the elderly. The recovery time depends on the nature of the fall, injuries caused and the physical condition of an individual. Minor injuries may take a few days to heal. Major injuries like fractures, brain injuries, etc, may take a few months to more than a year. Ask your doctor about the recovery plan and how long it might take in your specific case20

What is Tai Chi? How does it help reduce the risk of falls?? 

Tai Chi is a type of exercise routine used in China. It involves several `poses´ that use body weight and gravity to improve balance and strength. Movements like twisting of the torso, shifting of weight, squatting, and controlling the posture help with cognitive improvement. Tai Chi exercises may reduce the risk of falls by improving balance and strength21,22.     

Which yoga exercises can help reduce my risk of falls? 

Work under the supervision of a certified yoga teacher to learn `asanas´ or poses that improve balance and strength. Follow a simple yoga routine that is tailored to your fitness level and health conditions. To begin with, start with slow and simple exercises, gradually increasing in complexity to achieve the optimal benefits of yoga, and to reduce the risk of falls. Some such poses are:
Tree pose 
Dancer pose 
Crescent warrior pose 
Warrior III pose 
Side plank  
Figure 4 pose 
Upward and downward facing dog poses23,24

References 

  1. World Health Organization: WHO. Falls [Internet]. 2021. [Cited 2025 Aug 25]. Available from: https://www.who.int/news-room/fact-sheets/detail/falls 
  2. Vaishya R, Vaish A. Falls in Older Adults are Serious. Indian J Orthop. 2020 Jan 24;54(1):69-74.[Cited 2025 Aug 15]. doi: 10.1007/s43465-019-00037-x. PMID: 32257019; PMCID: PMC7093636. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7093636/
  3. Amaljith A, Marzo RR, Lekamwasam S, Kisa A, Behera A, S P, Saravanan PB, Shah PB, Mahapatra SS, Gopi K, P V, Swathika R, Baddar NU, John DM, Rajagopal V, Prevalence of fall and its associated factors among elderly population in India: Evidence from the Longitudinal Aging Study of India (LASI). The Evi. 2024:2(2):1-. DOI:10.61505/evidence.2024.2.1.47 [Cited 2025 Aug 15]. 
    Available From
    https://the.evidencejournals.com/index.php/j/article/view/47 
  4.  Biswas I, Adebusoye B, Chattopadhyay K. Risk factors for falls among older adults in India: A systematic review and meta-analysis. Health Sci Rep. 2022 Jun 21;5(4):e637. [Cited 2025 Aug 15]. doi: 10.1002/hsr2.637. PMID: 35774830; PMCID: PMC9213836. Available from: https://pubmed.ncbi.nlm.nih.gov/35774830/
  5. Joseph A, Kumar D, Bagavandas M. A Review of Epidemiology of Fall among Elderly in India. Indian J Community Med. 2019 Apr-Jun;44(2):166-168. [Cited 2025 Aug 15]. doi: 10.4103/ijcm.IJCM_201_18. PMID: 31333298; PMCID: PMC6625258. https://pmc.ncbi.nlm.nih.gov/articles/PMC6625258/
  6. National Center for Injury Prevention and Control. Stopping elderly accidents, deaths & injuries [Internet]. Centers for Disease Control and Prevention. 2017. Available from: https://www.cdc.gov/steadi/pdf/steadi-factsheet-medslinkedtofalls-508.pdf 
  7. NHS inform. Causes of falls | NHS inform [Internet]. NHS Inform. 2025. Available from: https://www.nhsinform.scot/healthy-living/preventing-falls/causes-of-falls/ 
  8. Lee AK, Juraschek SP, Windham BG, Lee CJ, Sharrett AR, Coresh J, Selvin E. Severe Hypoglycemia and Risk of Falls in Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2020 Sep;43(9):2060-2065. doi: 10.2337/dc20-0316. Epub 2020 Jul 1. PMID: 32611607; PMCID: PMC7440903. Available from: https://pubmed.ncbi.nlm.nih.gov/32611607/
  9. Appeadu MK, Bordoni B. Falls and Fall Prevention in Older Adults. [Updated 2023 Jun 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan- [Cited 2025 Aug 15].  Available from: https://www.ncbi.nlm.nih.gov/books/NBK560761/ 
  10. Falls Prevention Health Network. Health advice following a fall [Internet]. 2015. [Cited 2025 Aug 15]. Available from: https://www.health.wa.gov.au/~/media/Files/Corporate/general-documents/falls/PDF/12653-health-advice-following-a-fall-web-accessible.pdf 
  11. Stefanacci RG, Wilkinson JR. Falls in older adults [Internet]. MSD Manual Consumer Version. 2025. [Cited 2025 Aug 15]. Available from: https://www.msdmanuals.com/home/older-people-s-health-issues/falls-in-older-adults/falls-in-older-adults#Symptoms_v836662 
  12. The National Falls Prevention Resource Center and Resources Available | ACL Administration for Community Living [Internet]. Available from: https://acl.gov/programs/falls-prevention/national-falls-prevention-resource-center-and-resources-available 
  13. Falls compendium [Internet]. Older Adult Fall Prevention. 2025. [Cited 2025 Aug 15]. Available from: https://www.cdc.gov/falls/interventions/falls-compendium.html 
  14. Burns E, Kakara R, Moreland B, Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. A CDC COMPENDIUM OF EFFECTIVE FALL INTERVENTIONS: What Works for Community-Dwelling Older Adults [Internet]. Centers for Disease Control and Prevention; 2022. [Cited 2025 Aug 15].  Available from: https://www.cdc.gov/falls/pdf/Steadi_Compendium_2023_508.pdf 
  15. Biswas I, Adebusoye B, Chattopadhyay K. Health Consequences of Falls among Older Adults in India: A Systematic Review and Meta-Analysis. Geriatrics [Internet]. 2023 Apr 18;8(2):43. [Cited 2025 Aug 15]. Available from: https://doi.org/10.3390/geriatrics8020043 
  16. Falls prevention for older adults [Internet]. Department of Aging | Commonwealth of Pennsylvania. [Cited 2025 Aug 20].  Available from: https://www.pa.gov/agencies/aging/health-topics-for-older-adults/falls-prevention 
  17. Fall prevention tips [Internet]. mass.gov. [Cited 2025 Aug 20]. Available from: https://www.mass.gov/info-details/fall-prevention-tips-and-informational-resources 
  18. Jindal HA, Duggal M, Jamir L, Sharma D, Kankaria A, Rohilla L, Avasthi A, Nehra R, Grover S. Mental health and environmental factors associated with falls in the elderly in North India: A naturalistic community study. Asian J Psychiatr. 2019 Jan;39:17-21. doi: 10.1016/j.ajp.2018.11.013. Epub 2018 Nov 15. PMID: 30472349 Available from: https://pubmed.ncbi.nlm.nih.gov/30472349/ 
  19. Fall Risk assessment [Internet]. [Cited 2025 Aug 15].   Available from: https://medlineplus.gov/lab-tests/fall-risk-assessment/ 
  20. Tillou A, Kelley-Quon L, Burruss S, Morley E, Cryer H, Cohen M, Min L. Long-term postinjury functional recovery: outcomes of geriatric consultation. JAMA Surg. 2014 Jan;149(1):83-9. doi: 10.1001/jamasurg.2013.4244. PMID: 24284836; PMCID: PMC3947094.[Cited 2025 Aug 20]. Available from: https://pubmed.ncbi.nlm.nih.gov/24284836/
  21. Chen W, Li M, Li H, Lin Y, Feng Z. Tai Chi for fall prevention and balance improvement in older adults: a systematic review and meta-analysis of randomized controlled trials. Front Public Health. 2023 Sep 1;11:1236050. doi: 10.3389/fpubh.2023.1236050. PMID: 37736087; PMCID: PMC10509476. [Cited 2025 Aug 20]. Available from: https://pubmed.ncbi.nlm.nih.gov/37736087/
  22. Tai Chi: What you need to know [Internet]. NCCIH. .[Cited 2025 Aug 20]. Available from: https://www.nccih.nih.gov/health/tai-chi-what-you-need-to-know 
  23. Yazzie MK, Salt River Pima-Maricopa Indian Community. Yoga for elder fall Prevention: Pilot study of a 10-Week program for older adults in the Salt River Pima-Maricopa Indian community [Internet]. https://www.ihs.gov/sites/injuryprevention/themes/responsive2017/display_objects/documents/general-injury-prevention/Yoga_for_elder_fall_prevention_Pilot_study_of_a_10_week_program_for_older_adults.pdf 
  24. Harvard Health. Yoga balance workout [Internet]. Harvard Health. 2015. [Cited 2025 Aug 20].Available from: https://www.health.harvard.edu/exercise-and-fitness/yoga-balance-workout 

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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