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Home>QnA>Questions>Can Zerodol-SP cause swelling in the...

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Sim****
Sim****
Asked: January 7, 20262026-01-07T08:40:01+00:00 2026-01-07T08:40:01+00:00

Can Zerodol-SP cause swelling in the feet?

I’ve been taking Zerodol-SP for 2 days, and I’ve started noticing mild swelling in my feet. It’s not painful, just unusual. Could this be happening because of the medicine?

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  1. Dr. Nikita Toshi
    Dr. Nikita Toshi
    2026-01-07T08:58:19+00:00Added an answer on January 7, 2026 at 8:58 am

    Dear Reader,

    Swelling in the feet is not a common side effect of Zerodol SP. Swelling in the feet or ankles can be due to other causes, such as fluid retention, orthopedic problems, thyroid disorders, kidney problems, heart-related issues, high uric acid, or medications, including certain antihypertensive agents. 

    Zerodol-SP contains Aceclofenac, Paracetamol, and Serratiopeptidase. Of these, Aceclofenac (a nonsteroidal anti-inflammatory drug, or NSAID) can occasionally cause fluid retention. This happens because NSAIDs may affect how your kidneys handle salt and water, leading to slight swelling, especially if:

    • You’re taking the medicine for several days in a row
    • You already have high blood pressure, kidney, or heart issues
    • You’ve been sitting or standing for long periods

    What you can do:

    • Elevate your legs when resting to help reduce the swelling.
    • Stay hydrated, but avoid excessive salt intake.
    • Watch for warning signs such as shortness of breath, rapid weight gain, or swelling in both legs, which may require prompt medical attention.

    It is important to consult your doctor immediately. They may check your kidney function and rule out any other possible causes of swelling. If needed, they will suggest an alternative pain reliever that’s gentler on your system.

    Take care.

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Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment/advice by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

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