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Tolaz La 300mg Injection

By TORQUE PHARMACEUTICALS PVT LTD
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Tolaz La 300mg Injection Description

Tolaz La 300mg Inj belongs to the group of atypical antipsychotics used to treat psychiatric disorders like schizophrenia and manic and bipolar disorders. The active ingredient in Tolaz La 300mg Inj

is olanzapine. The mode of action of Tolaz La 300mg Inj is through its ingredient Olanzapine, which acts by regulating dopamine and serotonin levels in the brain, causing a reduction in the overexcitement of brain cells. It helps to reduce symptoms of acute schizophrenic episodes and is also used to maintain long-term schizophrenia. Tolaz La 300mg Inj helps to improve mood, behaviour, and general life responses. Tolaz La 300mg Inj comes as a white powder in a glass vial and is administered as an intramuscular injection by a qualified medical professional. Side effects of Tolaz La 300mg Inj include sleepiness, increased prolactin levels, weight gain, increased blood sugar, and sexual dysfunction. It can also cause orthostatic hypotension (dropping blood pressure by suddenly standing from a sitting or sleeping position). Abrupt stoppage may cause withdrawal symptoms or worsen side effects like dizziness, fainting, muscle tremors, and thinking difficulties. Limited data studies have shown that Tolaz La 300mg Inj may carry a risk causing obsessive-compulsive disorder (OCD) in users and increased risk of self-harm, especially among older adults. Therefore, regular monitoring is a must for persons with a history of self-harm or substance abuse. Tolaz La 300mg Inj is only given to children when the benefits outweigh the risks and side effects involved with Olanzapine.

modeOfAction

Product Summary

Offer Price₹1254.40
You Save₹204.20 (14% on MRP)
ContainsOlanzapine
UsesSchizophrenia, Bipolar disorder, Manic episodes
Side effectsSleepiness, Dizziness, Low blood pressure, Confused thinking, Prolactin elevation, Increased blood sugar levels, Sexual dysfunction
TherapyANTI-PSYCHOTICS
molecules
Check more medicines with composition as Olanzapine
uses

Uses of Tolaz La 300mg Injection

  • Tolaz La 300mg Inj is used to treat:
  • Onset of acute schizophrenia
  • Therapeutic care of long-term schizophrenia
  • Bipolar disorder
  • Manic episodes or mania
contraindications

Contraindications of Tolaz La 300mg Injection

  • Tolaz La 300mg Inj should not be given to/given with caution:
  • If you are an older adult with dementia
  • If you have high glucose levels after use or pre-existing diabetes
  • If you have bleeding disorders
  • If you have a history of seizures
  • If you have a history of brain tissue disorders
  • If you have a history of or presently have cardiac ailments
  • If you have low magnesium or potassium levels
  • If you are obese
  • If you have low blood pressure
  • If you have been diagnosed with obsessive-compulsive disorder (OCD)
  • If you have closed-angle glaucoma (increased intra-eye pressure due to angle defects between the iris and cornea)
sideEffects

Side effects of Tolaz La 300mg Injection

  • Side effects of Tolaz La 300mg Inj include:
  • Increased glucose levels
  • Orthostatic hypotension (drop in blood pressure by suddenly standing from a sitting or sleeping position)
  • Increase prolactin levels
  • Blurry vision
  • Uncontrolled muscle tremors
  • Dizziness
  • Headache
  • Increased heart rate
  • Weight gain
  • Sexual dysfunction
  • Gynecomastia (enlarged breast in males)
precautionsAndWarnings

Precautions and Warnings of Tolaz La 300mg Injection

pregnancy

Pregnancy

Q:
Can I take Tolaz La 300mg Inj during pregnancy?
A:
No. Reported clinical data shows that Tolaz La 300mg Inj can cause harmful effects on the foetus like decreased limb movements in the latter part of pregnancy. Consult your physician if you get pregnant or are planning a pregnancy while taking this medication.
breastfeeding

Breast Feeding

Q:
Can I take Tolaz La 300mg Inj while breastfeeding?
A:
No. Animal studies have shown Tolaz La 300mg Inj to excrete into breast milk. Therefore, it might not be safe to take this injection while breastfeeding. Consult your physician.
driving

Driving

Q:
Can I drive if I have been given a Tolaz La 300mg Inj ?
A:
Driving or operating a vehicle/heavy machinery is not advised after taking Tolaz La 300 mg inj. Consult a physician to know when you can get back to driving after taking the injection.
alcohol

Alcohol

Q:
Can I consume alcohol while taking Tolaz La 300 mg inj?
A:
No. Consuming alcohol while taking Tolaz La 300mg Inj may increase the severity of its side effects like dizziness, low blood pressure, tremors, and confused thinking.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You develop an allergy to Tolaz La 300 mg Inj.
  • You do not wish to take Tolaz La 300 mg Inj.
  • You have severe and persistent effects.
  • You have noticeable paradoxical side effects like aggression and self-harm.
  • You face any other medical issues after taking Tolaz La 300 mg Inj.
modeOfAction

Mode of Action of Tolaz La 300mg Injection

How Does It Work?

Tolaz La 300mg Inj is primarily used to treat schizophrenia, acute schizophrenic episodes, manic events, long-term control of schizophrenia, and when other treatments have not helped. Tolaz La 300mg...
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directionsForUse

Directions for Use of Tolaz La 300mg Injection

  • A box of Tolaz La 300mg Inj contains the medication in powder form in a glass vial to be constituted with sterile liquid for the injection. It is given intramuscularly in the gluteus muscle (lower bac...
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  • Tolaz La 300mg Inj is given weekly or once every 2/4 weeks depending on the affected person's condition and after consultation with a physician.
  • Proper inspection of the vial is a must before administering. It should be inspected for expiry, particulate matter, or any discolouration. The unused liquid in the vial and the needle/syringe should ...
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  • Tolaz La 300mg Inj carries a risk of developing post-injection syndrome (increased sedation, confused thoughts, difficulty in speech, and uncoordinated muscle and limb movements). All persons being ad...
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  • Tolaz La 300mg Inj should never be self-administered or taken with the help of a non-medical person or without the knowledge and consent of the treating doctor.
  • Do not stop taking Tolaz La 300mg Inj on your own even if you have started feeling better. It may cause withdrawal symptoms like dizziness, vision disturbances, and fainting. The dosage has to be tape...
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interactions

Interactions of Tolaz La 300mg Injection

Interactions with other medicines

  • Tolaz La 300mg Inj is known to interact with the following medications. They should not be given or given with caution when on treatment with Tolaz La 300mg Inj.
  • Bromocriptine and cabergoline (medicines to treat prolactin levels in the blood) reduce the efficacy of Tolaz La 300mg Inj.
  • Dopamine, apomorphine, and lisuride (used in Parkinson's therapy) decreases the action of Tolaz La 300 mg inj.
  • Fluvoxamine (antidepressant) increases Olanzapine levels in the blood.
  • Levodopa and methyldopa (blood pressure medication) severely decrease blood pressure.
  • Mefloquine (anti-malarial) increases the side effects of bipolar disorder.
  • Pramipexole and ropinirole (Parkinson's medication) may counter effect Olanzapine.
  • Sodium oxybate (medication for muscle lethargy and general weakness) can cause respiratory problems like breathing difficulties.
  • Vilanterol + Fluticasone (medication for asthma and COPD ) increases toxicity causing dizziness, fainting, or coma.
  • Carbamazepine (anticonvulsant) decreases the efficacy of Tolaz La 300mg Inj.
  • Diazepam and lorazepam (sedatives) increase dizziness and sedation.

Interactions with food items

  • Avoid a high-sugar diet. Tolaz La 300mg Inj causes high blood sugar and weight gain, so an appropriate diet is recommended after consultation with a doctor.
storageAndDisposal

Storage and disposal of Tolaz La 300mg Injection

Tolaz La 300mg Inj vials are kept in a hospital setting between 20-25 ℃. They should be kept away from direct sunlight and stored away from potential misuse, and not at home. Tolaz La 300mg Inj vials ...
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dosage

Dosage of Tolaz La 300mg Injection

Overdose

Overdose is a rare possibility with Tolaz La 300mg Inj as it is strictly administered in a hospital setting by a medical professional. Accidental/intentional overdose may cause low blood pressure, rap...
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Missed a Dose

Inform your physician if you will miss your scheduled Tolaz La 300mg Inj so it can be rescheduled for later.

Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)

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Q: When will I see the effects of Tolaz La 300mg Inj?

A: Most antipsychotic injectables require at least 1-3 weeks to start working effectively in cases of schizophrenia. You may need to wait up to 2 weeks to start feeling better. Consult a physician if you do not feel better even after taking 2-4 injections of Tolaz La 300mg Inj.

Q: Will Tolaz La 300mg Inj make me sleepy?

A: Yes. You may feel very sleepy, especially on the day of taking the injection. Olanzapine in Tolaz La 300mg Inj reduces the excitability of nerve cells, thus enhancing the sleep effect.

Q: Can I take Tolaz La 300mg Inj if I have kidney problems?

A: Most reported data suggest that Tolaz La 300mg Inj can be safely prescribed to persons with kidney disease. No significant dose adjustment is generally required.
Last Updated on: 21 Mar 2022 | 10:52 AM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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