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molecule

Penicillamine

Molecule Description

Penicillamine is ‘Disease Modifying Anti Rheumatic Drug (DMARD)’ primarily used

for the treatment of Wilson’s disease (a rare genetic disorder which causes copper accumulation in the body) and Rheumatoid Arthritis.

uses

Uses of Penicillamine

  • Wilson’s disease
  • In severe rheumatoid arthritis that has not responded to other treatment
  • In cystinuria (excess of an amino acid called cystine in the urine which causes kidney stones)
  • Lead metal poisoning
  • Liver disease called chronic active hepatitis in adults
contraindications

Contraindications of Penicillamine

When should one not use Penicillamine

  • Do not take this medicine if you have an allergy to this medicine
  • After taking this medicine your white blood cells, platelets and red blood cells count decreases
  • You have systemic lupus erythematosus, a disease in which the body attacks its healthy tissue
  • You have kidney disease
sideEffects

Side effects of Penicillamine

Common side effects of this drug are:

  • Bleeding through nose, gums, etc.
  • Skin bruise
  • Appearance of protein in urine
precautionsAndWarnings

Precautions and Warnings of Penicillamine

pregnancy

Pregnancy

Q:
Can I take Penicillamine during pregnancy?
A:
It is probably considered unsafe to use this medicine during pregnancy, as it can cause adverse effects on unborn babies. Consult your doctor before taking this medicine.
breastfeeding

Breast Feeding

Q:
Can I take Penicillamine while breastfeeding?
A:
This medicine can pass into breast milk and can cause adverse effects on the breastfed baby, therefore avoid this medicine in breastfeeding. Consult your doctor for advice.
driving

Driving

Q:
Can I drive if I have consumed Penicillamine?
A:
Using this medicine usually does not usually affect your ability to drive.
alcohol

Alcohol

Q:
Can I consume alcohol with Penicillamine?
A:
No study found about an interaction of this medicine with alcohol.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have allergy with gold or medicines containing gold
  • Your urine contains protein or blood
  • You have low white blood cell count
  • Your age is more than 60 years
modeOfAction

Mode of Action of Penicillamine

How Does It Work?

This medicine reduces the unusual response of the body's immune system in Rheumatoid Arthritis. It also acts by binding to accumulated copper and lead and its elimination through the body.
interactions

Interactions of Penicillamine

Interactions with other medicines

  • Gold, Ibuprofen, Naproxen, Clozapine increase the side effects of this medicine when taken together
  • Iron medicine, antacids, zinc can change the effectiveness of this medicine
  • Digoxin

Interactions with food items

No specific interactions with food have been reported yet.
dietaryRestrictions

Dietary Restrictions of Penicillamine

No data available.
dosage

Dosage of Penicillamine

Overdose

Consult your doctor as soon as possible if you consume more medicine than your usual dosing.

Missed a Dose

Take the missed dose as early as you remember. If the time for next dose is near, skip the missed dose and do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What should I discuss with my healthcare expert before taking this medicine?

A: You should not use this medicine if you are allergic to it, if you have kidney disease, liver disease, a history of stomach ulcers, a weak immune system or if you are malnourished.

Q: When should I consult a doctor if I am on treatment with this medicine?

A: Consult your doctor if there is severe joint and muscle pain when you are on treatment with this medicine.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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