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molecule

Omeprazole+Domperidone

Molecule Description

Omeprazole+Domperidone is a combination medicine. It is an anti-reflux medicine

used for the treatment of gastrointestinal reflux disease (GERD) which does not respond to omeprazole. It provides relief from symptoms of acid reflux disease like heartburn and chest discomfort. Both the medicines, together work by reducing the amount of acid produced in the stomach and improves the mortality in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Omeprazole+Domperidone is available in the form of tablet, capsule, injection.

uses

Uses of Omeprazole+Domperidone

Omeprazole+Domperidone is used to treat gastrointestinal reflux disease (GERD), not responding to omeprazole alone.
contraindications

Contraindications of Omeprazole+Domperidone

When should one not use Omeprazole+Domperidone

  • If you are allergic to omeprazole+domperidone
  • If you have problems with your heart, liver or kidney.
  • If you suffer from bleeding in the digestive system.
  • If you have problems relating to the bones such as osteoporosis and a fracture.
  • If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
  • If you have low magnesium levels in your blood.
sideEffects

Side effects of Omeprazole+Domperidone

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Stomach pain
  • Diarrhoea
  • Dry mouth
  • Injection site reactions
precautionsAndWarnings

Precautions and Warnings of Omeprazole+Domperidone

pregnancy

Pregnancy

Q:
Can I take omeprazole+domperidone during pregnancy?
A:
It is not advised to take omeprazole+domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.
breastfeeding

Breast Feeding

Q:
Can I take omeprazole+domperidone while breastfeeding?
A:
Omeprazole+Domperidone passes in the breastmilk in a small amount. Your doctor may prescribe you this medicine while you are breastfeeding, only if it is necessary. Inform your doctor if you are a nursing mother.
driving

Driving

Q:
Can I drive if I have taken omeprazole+domperidone?
A:
Omeprazole+Domperidone may cause dizziness, thus you need to be cautious while driving.
alcohol

Alcohol

Q:
Can I consume alcohol with omeprazole+domperidone?
A:
Avoid consuming alcohol with omeprazole+domperidone, as it may worsen the side effects.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You suffer from any heart problems such as heart failure, heart rhythm problems, electrolyte imbalance
  • You have problems with your liver or kidney.
  • You have a stomach tumour/cancer
  • You are taking medicines to treat HIV.
  • You have a history of fractures or have osteoporosis or are taking steroids.
  • You develop watery/black stools or fever after taking omeprazole+domperidone.
  • You get rashes on your skin on exposure to sun after taking this medicine.
  • Your blood magnesium levels may drop, if you are taking this medicine for more than three months. Your doctor may perform regular tests.
  • Taking omeprazole+domperidone for more than one year may increase the chances of developing bone fractures.
modeOfAction

Mode of Action of Omeprazole+Domperidone

How Does It Work?

  • A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Omeprazole works by binding to this proton pump in stomach cells, thus blocking acid secretion.
  • Domperidone works by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.
interactions

Interactions of Omeprazole+Domperidone

Interactions with other medicines

  • Some medicines can affect the way omeprazole+domperidone works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines...
    Read more
  • Especially if you are taking medicine to treat your heart problems, psychiatric illnesses, HIV infection, fungal or bacterial infections or are taking blood thinners or medicines like methotrexate, ta...
    Read more
  • Medicines like clopidogrel, atazanavir, nelfinavir, erythromycin, posaconazole, ketoconazole, itraconazole should not be used along with this combination.

Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: Is omeprazole+domperidone an antibiotic?

A: No, omeprazole+domperidone is not an antibiotic, it is an anti-reflux medicine.

Q: In which all dosage forms is omeprazole+domperidone available?

A: Omeprazole+Domperidone is available in the form of tablet, capsule, injection.
Last Updated on: 19 Nov 2021 | 10:55 AM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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