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About the test
What is this test done for?
It is test to measure the amount of Vitamin B12 level in the blood.
Why is it Done?

It is done –

  • To assess deficiency of this vitamin that an cause megaloblastic anaemia
  • To monitor treatment with B12 supplements
  • As part of pre-natal screening panel
When should it be performed?

It is done when patients complain of any of the following signs and symptoms- Patient complains of tiredness even after sleeping well.

  • Lack of energy in normal activities.
  • Complaining of memory or mood problems.
  • Complains of weakness, dizziness, has pale skin & headache.
  • Numbness & coldness of hands & feet.
  • Low body temperature.
  • Shortness of breath, chest pain.
  • Anaemia like iron deficiency anaemia, aplastic anaemia, thalassemia, sickle cell anaemia.
  • Children eating pica i.e. clay, ice etc.
  • Women with excessive menstrual bleeding.
How is it done
A blood sample will be collected from a vein in your arm. Fasting is not required prior to sample collection.

Normal values:  81 -1107 picomoles per litre

High values are seen in conditions like  liver disease, cirrhosis, hepatitis, obese people with  diabetes.

Low values are seen in conditions likedeficiency of vitamin B12 .

  • Due to pernicious anaemia.
  • dietary B12 deficiency
  • Folic acid deficiency.
  • Hyperthyroidism, multiple myeloma.
  • Gastric malabsorption of B12 due to any surgical procedure of the stomach or ileum, tropical sprue, celiac disease, etc.
Other Tests
Other tests like folic acid, MMA blood test, homocysteine levels may also be done to assess cause of anaemia, etc.
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