What is this test done for?
Serum protein electrophoresis (SPEP) is an easy and inexpensive blood test used to determine the levels of protein subtypes in the blood sample.
Why is it Done?
SPEP is generally done in any patient with an elevated total protein count on liver function test.
When should it be performed?
It is especially ordered in patients with elevated globulin level relative to albumin (in liver profile analysis). It is also done if there are any signs and symptoms such as unexplained anemia, back pain, bone pain, fatigue, or pathologic fracture, kidney insufficiency with bland urine sediment, or recurrent infections (suggesting an underlying plasma cell disorder such as multiple myeloma), Waldenstrom’s macroglobulinemia, or primary amyloidosis.
How is it done
A blood sample will be collected from a vein in your arm. Fasting is not needed prior to sample collection.