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About the test
What is this test done for?
To check the level of Dehydropiandrosterone – sulphate hormone in the blood & evaluate the functioning of adrenal glands.
Why is it Done?

It is done along with other hormonal tests:

  • In women to diagnose PCOS.
  • To check for congenital adrenal hyperplasia.
  • As screening panel for infertility.
  • As screening panel for delayed puberty.
  • Cushing’s disease.
  • Tumour in the adrenal gland.
  • To check depression & mental function.
When should it be performed?

When the patient presents with symptoms of:

  • No menses since over 2-3 months.
  • Infertility.
  • Virilization  having men-like characteristics like excess facial or body hair, acne, deep voice, decrease breast size, muscularity in women.
  • Infants with ambiguous genitalia.
How is it done

Minimum 8 hours fasting is needed before the test without food or liquid (except water). A blood sample will be collected from a vein in your arm in the morning when the amount of DHEAS is highest. If medication like aspirin, steroids, amlodipine, & supplements of DHEAS are being taken should be avoided for sometime before the test is done.


The normal values are in the reference range. These ranges vary from lab to lab. These values vary with age & the phase of life like women before menopause, after menopause etc. Levels can be high or low. Low levels can be seen in following conditions -

  • In males the adrenal glands are not making enough male sex hormones.
  • In females the adrenal glands are not making enough female sex hormones.
  • An adrenal gland has a tumour.
  • Condition like chronic fatigue syndrome, ulcerative colitis.

High levels can be –

  • Because of stress.
  • Hyperthyroidism.
  • Polycystic ovary syndrome.
  • Congenital adrenal hyperplasia.
  • Adrenal tumours.
Other Tests
Testosterone, estradiol levels, FSH, LH, Prolactin levels should be done to assess the exact cause.
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