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About the test
What is this test done for?
CPK-MB is a test done to distinguish between disease originating in skeletal and heart muscle.
Why is it Done?
The test is done to determine heart attack and to monitor for additional heart damage. It was one of the primary tests for detection of heart or skeletal muscle disease for a very long time, until it was replaced by troponin-I test. If troponin-I, is not available then CPK-MB is still considered.
When should it be performed?

If there are following symptoms or conditions then SGOT test is performed:

  • Shortness of breath
  • Nausea and vomiting
  • Chest pain
  • Extreme fatigue
  • Dizziness
  • It is ordered within 3 to 6 hours of chest pain.
How is it done
A blood sample will be collected from a vein in your arm. If there is chest pain, then it is to perform the test within 3 to 6 hours.

Normal levels for males is 5 to 25 IU/L.

Elevated results suggest that following conditions are possible:

  • Damage of skeletal muscles like heart
  • Trauma, surgery, inflammation or decreased oxygen
  • Kidney failure
  • Rarely chronic muscle disease, low thyroid hormone (T3, T4)
  • Alcohol abuse
Other Tests
Troponin-I is a confirmatory test to detect heart attack along with an electrocardiogram (ECG).
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