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CMV ANTIBOBY IGG

About the test
What is this test done for?
The CMV antibody IgG test is done for diagnosing past infection with cytomegalovirus (CMV) in people infected with mononucleosis or in pregnant women.
Why is it Done?
This test is done in cases where a CMV infection is suspected. In young adults, immune-comprised persons, or pregnant women when flu like symptoms appear, it could suggest a CMV infection. Furthermore, in a new born baby with multiple congenital abnormalities, anemia, and developmental problems, doctors may suggest testing for CMV antibody IgG along with IgM. It is also tested just prior to receiving an organ transplant.
When should it be performed?

The test should be performed when following symptoms are seen:

  • Fatigue,
  • Weakness
  • Sore throat
  • Fever
  • Headache
  • Muscle pain or general body pains
  • Enlarged lymph nodes in the body
How is it done
A blood sample will be collected from a vein in your arm. Fasting is not required for the test.
Results

CMV antibody IgG is reported as: positive, negative, or equivocal.

  • Positive CMV IgG results indicate past CMV infection. These individuals may transmit CMV to susceptible individuals through blood and tissue products.
  • Individuals with negative CMV IgG results are presumed to not have had prior exposure or infection with CMV, and are therefore considered susceptible to new infection.
  • Equivocal CMV IgG results may occur during acute infection or may be due to non-specific binding reactions. Submit an additional sample for testing if clinically indicated.
Other Tests
  • Cytomegalovirus IgM: to detect an active phase of infection.
  • TORCH test: CMV is a part of TORCH (an acronym for Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes simplex virus). Therefore, is done for screening pregnant women for fetal deformities or in those having history of habitual abortions.
  • A kidney profile is also done after the CMV tests (especially if the results are positive) to rule out any kidney complications.
  • Tests for influenza A IgG and IgM, influenza B IgG and IgM , Epstein-Barr virus DNA PCR should be done.
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