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CARDIOLIPIN IGA

About the test
What is this test done for?
Cardiolipin IgA is a test done to detect the presence of cardiolipin antibodies in the blood.
Why is it Done?
Cardiolipin IgA is a test which helps to investigate inappropriate blood clot formation. It is also done as a part of an evaluation for antiphospholipid syndrome or other autoimmune diseases.
When should it be performed?

The test is performed when individual has symptoms of blood clot, especially if it is recurrent. The signs and symptoms depend on the location where the clot is formed:

  • In deep veins:
    • Leg pain or tenderness, usually one leg
    • Swelling of legs
    • Discolouration in skin of legs
  • In lungs:
    • Sudden shortness of breath.
    • Laboured breathing
    • Coughing
    • Blood stained cough
    • Lung related chest pain
  • Rapid heart rate
It is also performed when a women has recurrent miscarriages.
How is it done
A blood sample will be collected from a vein in your arm. Fasting is not needed prior to sample collection.
Results
  • The levels for low positive results: Fewer than 20 G phospholipids (GPL), M phospholipids (MPL), A phospholipids (APL) units
  • The levels of medium positive results: 20 or more but fewer than 80 GPL, MPL, APL units.
  • The levels of high positive: 80 or more GPL, MPL, APL units.
A negative result mostly suggests that the antibodies are not detectable at that particular time. Positive results should be obtained twice with a 12 week gap between the tests to validate the diagnosis.
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