CA-125 is usually done as a screening test.
Positive test results mean that the patient is having more than 35 units per mL of the antigen and indicates ovarian cancer. However, many other health conditions can also elevate the levels. These include the following:
Negative test results mean that the patient does not have ovarian cancer.
Any result of the CA-125 test should be supplemented with transvaginal sonography, rectovaginal pelvic examination, and serial CA-125 testing.