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CRP (C-Reactive-Protein)

About the test
What is this test done for?
CRP stands for C-reactive protein. This is a blood test that measures the amount of CRP in the blood.
Why is it Done?
  • This is a specialized blood test marker for detecting inflammation in the body. CRP is known as an acute phase reactant, which means its level rises immediately in response to inflammation.
  • CRP helps in identifying and monitoring diseases that cause inflammation (diseases like cancer, lupus, rheumatoid arthritis and infections like tuberculosis, osteomyelitis). It also helps in monitoring how well the treatment is working, like in cancer or rheumatoid arthritis.
When should it be performed?

This test is performed to

  • Diagnose diseases
    • Autoimmune diseases like rheumatoid arthritis, lupus (SLE)
    • Giant cell arteritis
    • Cancer
    • Inflammatory bowel diseases
      • Crohn’s disease
      • Ulcerative colitis
  • Identify infection
    • Tuberculosis (TB)
    • Osteomyelitis
  • Tracking the treatment of diseases
    • Rheumatoid arthritis
    • SLE
    • Cancer
How is it done
A blood sample will be collected from a vein in your arm. No special preparations like fasting required.
Results

The test result is normal, if levels are < 10 mg/L. It means

  • No active inflammation
  • No source of active inflammation
  • Good response to therapy for autoimmune diseases like lupus, rheumatoid arthritis and diseases like cancer

The test results are high, if levels are > 10 mg/L. It means

  • Active inflammation is present in the body, which can happen in
    • Trauma
    • Infections
      • Acute infections (it increases and drops quickly)
      • Tuberculosis (it remains high for a longer duration)
      • Osteomyelitis (it remains high for a longer duration)
    • Burns
    • Heart attack
    • Stroke
    • Cancer
  • Inflammation present in autoimmune diseases like
    • Rheumatoid arthritis
    • Lupus or SLE (Systemic Lupus Erythematosus)
    • Giant cell arteritis
    • Inflammatory bowel diseases (Crohn’s disease or ulcerative colitis)
Other Tests
  • ESR
    • It is a routine blood test carried out to evaluate the sedimentation of RBCs at the end of 1 hour
    • High levels of ESR indicate inflammation
  • Haptoglobin levels
    • It is a specialized blood test carried out to evaluate the amount of haptoglobin present in the blood
    • High levels of haptoglobin indicate active inflammation in the body
  • Complement factors
    • It is a specialized test carried out to evaluate complements that help to tackle infection
    • High levels of complement factors indicate active inflammation due to infection
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