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About the test
What is this test done for?
C- peptide is a blood test to help evaluate insulin production by the pancreas or to determine the cause of low blood glucose levels.
Why is it Done?
C- peptide is a protein produced by beta cells in pancreas along with insulin. C-peptide and insulin are produced at the same rate, making C-peptide a useful marker of insulin production. It is not used for diagnosis of diabetes. It may be used to diagnose insulinomas, a tumor of the insulin producing cells of pancreas. In some cases, it helps to evaluate people diagnosed with metabolic disorders include abdominal obesity, increased blood glucose, unhealthy lipids or hypertension.
When should it be performed?

This test is done when the following signs and symptoms:

  • Sweating
  • Palpitations
  • Hunger
  • Confusion
  • Blurred vision
  • Fainting
  • Seizures and loss of consciousness.
How is it done
A blood sample will be collected from a vein in your arm. The test is done after 12 hours of fasting.
The normal values are 0.8 to 3.1 ng/mL. High levels indicate usually high level of endogenous insulin production which is due to high blood glucose. It may also indicate insulinomas but need to be confirmed with other tests. It is low when a patient is diabetic and production of insulin is suppressed by external treatment.
Other Tests
For diabetes, fasting and post prandial blood glucose levels can be assessed. Potassium, antiphospholipids antibodies, renal function test to confirm the diagnosis of insulinomas might be necessary tests.
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