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Bilirubin (T+D)

About the test
What is this test done for?
Bilirubin is a routine blood test that measures the amount of bilirubin levels in the blood. Bilirubin is of two types, i.e., conjugated and unconjugated; thus, usually two most common form evaluated are total bilirubin and direct (conjugated) bilirubin.
Why is it Done?
This is a routine blood test that checks for the amount of direct and total bilirubin present in the blood. This helps in the evaluation of liver functions, as conjugation of bilirubin occurs in the liver. The amount of bilirubin rises in patients with a damaged liver.The test is done for
  • Identifying diseases of the liver and bile duct
  • For monitoring diseases of the liver and bile duct
  • Evaluating patients who have sickle cell anemia or other hemolytic anemia
  • Identifying the cause of jaundice in the new born
When should it be performed?
This test is performed
  • If a patient presents with symptoms of liver diseases
    • Jaundice
    • Abdominal pain
    • Nausea
    • Vomiting
    • Loss of appetite
    • Weakness and fatigue
    • Itching
  • For measuring and monitoring newborns having jaundice
How is it done
A blood sample will be collected from a vein in your arm. No special precautions like fasting required.
Results
The test result is normal, if levels of total bilirubin are 0.2-1.2 mg/dL and of direct bilirubin is 0.1-0.4 mg/dL. It means
  • No liver disease
  • No hemolysis
The test results are abnormal, if levels of total bilirubin are >1.5 mg/dL and normal level of direct bilirubin. It means
  • High levels of unconjugated bilirubin
  • Hemolytic or pernicious anemia
  • Transfusion reaction
  •  Liver cirrhosis
  • Gilbert’s syndrome
  • Drug reaction
  • Alcoholic liver disease
The test results are abnormal, if levels of total bilirubin are >2.5 mg/dL and of direct bilirubin are >1 mg/dL. It means
  • Gall stones, obstructing the bile duct
  • Tumors that obstruct the bile duct, such as tumor of the head of pancreas
  • Scarring of the bile duct
In newborns, high bilirubin level may be temporary and resolves in a few days to weeks but if it increases rapidly above the threshold level a thorough investigation is carried out to rule out the cause of such high levels of bilirubin. Bilirubin levels are high in children either due to increased RBC destruction caused by Rh incompatibility, congenital infections, lack of oxygen, or liver diseases. High levels of direct bilirubin are also seen in neonatal hepatitis or biliary atresia.
Other Tests
  • SGOT
    • High levels of SGOT indicate liver diseases like hepatitis and cirrhosis
  • SGPT
    • High levels of SGPT indicate liver diseases like hepatitis, cirrhosis, alcohol related liver disease
  • Alkaline Phosphatase
    • High levels of alkaline phosphatase indicate liver disease
  • GGTP
    • High levels of GGTP indicate liver disease
    • GGTP levels help in differentiating between bone and liver diseases
    • GGTP levels are normal in case of bone diseases
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