The following can help to assess:
- High risk: CHD or CHD risk equivalent
- ApoB < 90 mg/dL / LDL-C< 100 mg/dL
- Moderate risk: ≥ 2 risk factors
- ApoB < 110 mg/dL / LDL-C < 130 mg/dL
- Low risk: 0-1 risk factors
- ApoB < 130 mg/dL / LDL-C < 160 mg/dL
Abnormal levels of Apo- b are seen in:
- Use of certain medications like androgens, beta blockers etc.
- Nephrotic syndrome
- Pregnancy (temporary)
Apo-B may decrease with:
- Physical exercise.
- Weight reduction
- Severe illness
- Reye syndrome
- Use of certain medications like statins, estrogens, oral contraceptives.
High ratio of Apo A-1 and Apo B are associated with the risk of cardiovascular disease.