Reference range is as follows:
Men- abnormal if greater than 120mg/dL
Women- abnormal if greater than 140mg/dL.
Apo A-1 may decrease with:
- Chronic kidney disease
- Use of certain medications like androgens, beta- blockers
- Uncontrolled diabetes
Apo A-1 may increase with:
- Physical exercise.
- Weight reduction
- Use of statins (lipid lowering drugs)
- Use of certain medications like estrogens, oral contraceptives, Phenobarbital.
Low Apo A-1 and high Apo B are associated with the risk of cardiovascular disease.