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ANTI PHOSPHOLIPID IGG

About the test
What is this test done for?
Anti phospholipid antibodies IgG is a screening test for the quantitative determination of the IgG antibodies.
Why is it Done?
This test is used to determine the cause of:
  • Inappropriate blood clot formation.
  • Recurrent miscarriage/ abortion
  • Low platelet count
  • Prolonged Prothombin time test (PTT).
When should it be performed?
The test is performed when the signs and symptoms are suggestive of blood clot, symptoms like pain and swelling in the extremities, shortness of breath, headaches. In women, it is done when she has experienced recurrent miscarriages and prolonged PTT. Depending on the signs and symptoms following more tests may be performed:
  • Cardiolipin antibodies are the ones frequently ordered since they are the most common antiphospholipid antibodies.
  • Lupus anticoagulant assays are done if a person has a prolonged PTT test.
  • Beta-2 glycoprotein 1 testing may be ordered along with the other antiphospholipid antibodies to detect their presence.
How is it done
A blood sample will be collected from a vein in your arm. Fasting is not needed prior to sample collection.
Results
If the antibodies test is negative it means that it is negative for that particular strain which is been tested. If the results for that antibody are positive, it would means that the antibody is present. Strong positive results for antiphosopholipid antibody suggests presence of antiphospholipid syndrome. Occasionally, it is also tested for determining the cause for positive VDRL for syphilis.
Other Tests
VDRL test is performed in order to confirm syphilis as antiphospholipid antibodies are often present if VDRL is positive. As reagents for syphilis contain phospholipids, it can cause false positive results.
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