{"id":277844,"date":"2026-05-08T13:29:06","date_gmt":"2026-05-08T13:29:06","guid":{"rendered":"https:\/\/pharmeasy.in\/blog\/?p=277844"},"modified":"2026-05-08T14:04:11","modified_gmt":"2026-05-08T14:04:11","slug":"diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention","status":"publish","type":"post","link":"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/","title":{"rendered":"Folate Deficiency: Meaning, Causes, Symptoms, Treatment &amp;\u00a0Prevention\u00a0"},"content":{"rendered":"<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><head><meta http-equiv=\"Content-Type\" content=\"text\/html; charset=utf-8\">\n<\/head><body><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69fec7976ef8c\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"ez-toc-cssicon\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69fec7976ef8c\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Introduction\" >Introduction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#What_Is_Folate_Deficiency\" >What Is Folate Deficiency?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Why_Is_Folate_Important_for_the_Body\" >Why Is Folate Important for the Body?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Symptoms_of_Folate_Deficiency\" >Symptoms of Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Causes_of_Folate_Deficiency\" >Causes of Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Risk_Factors_for_Folate_Deficiency\" >Risk Factors for Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Folate_Deficiency_in_Pregnancy\" >Folate Deficiency in Pregnancy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Complications_of_Folate_Deficiency\" >Complications of Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Diagnosis_of_Folate_Deficiency\" >Diagnosis of Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Treatment_of_Folate_Deficiency\" >Treatment of Folate Deficiency<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#How_to_Manage_Folate_Deficiency_Naturally\" >How to Manage Folate Deficiency Naturally?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#When_to_See_a_Doctor\" >When to See a\u00a0Doctor?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Conclusion\" >Conclusion<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#Frequently_Asked_Questions_FAQs\" >Frequently Asked Questions (FAQs)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/pharmeasy.in\/blog\/diagnostic-folate-deficiency-meaning-causes-symptoms-treatment-prevention\/#References\" >References<\/a><\/li><\/ul><\/nav><\/div>\n    <a rel=\"nofollow\" href=\"https:\/\/pharmeasy.in\/blog\/channel-health-talk\"\n       class=\"pe-healthtalk-banner\"\n       style=\"position:relative; display:block; margin:10px; border-radius:10px; border-bottom:2px solid #117B77; overflow:hidden;\">\n        <span aria-hidden=\"true\" style=\"position:absolute; left:0; bottom:0; width:2px; height:50%; background:#10847e;\"><\/span>\n        <img alt=\"Join Health Talk by PharmEasy on WhatsApp\"\n             src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/PEhealthtalk-1.png\"\n             style=\"width:100%; display:block; border-radius:10px;\">\n    <\/a>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Introduction\"><\/span><strong>Introduction<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Vitamins are essential substances that our body\u202fneeds to stay healthy and function properly. They play a key role in a variety of functions, including,\u00a0helping in\u00a0energy production, immunity, growth, and tissue repair. One such important vitamin is folate (vitamin B9).\u00a0Folate plays a key role in the formation of red blood cells and in the making of DNA, which is the genetic material present in all our cells<sup><a href=\"https:\/\/medlineplus.gov\/ency\/article\/002399.htm\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.<\/p>\n\n\n\n<p>When the body does not receive enough folate, it develops\u00a0folate deficiency.\u00a0This is a more prevalent dietary condition that can affect people of any age, including children, adults, pregnant women, and older people. Because folate is essential for healthy blood and cell formation, its\u202fdeficiency can lead to a variety of health problems if not handled properly<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<p>Understanding the causes, symptoms, treatment, and prevention of folate deficiencies is critical because it aids in the early detection and effective management of this condition, resulting in improved health and well-being.\u00a0In this article, we will discuss on all these topics.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Folate_Deficiency\"><\/span><strong>What Is Folate Deficiency?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>As mentioned earlier, folate deficiency is a condition that develops when the body does not have enough folate to meet its daily needs.\u00a0It\u00a0means your body is lacking an important vitamin that is necessary for making new cells and healthy red blood cells.\u00a0<\/p>\n\n\n\n<p>When folate levels are inadequate, the body struggles to make adequate normal red blood cells.\u00a0Instead, the bone marrow produces large, immature, and abnormal cells that\u00a0don\u2019t\u00a0work properly.\u00a0This can result in folate-deficiency anaemia, a condition in which the blood\u00a0fails to\u00a0transport enough oxygen to the body\u2019s tissues. As a result, a person may experience weakness, fatigue, and a lack of energy.\u00a0Low folate levels can\u00a0also\u00a0slow down the body\u2019s ability to make DNA properly.\u00a0<\/p>\n\n\n\n<p>Folate deficiency can develop gradually over time, often due to\u202fa poor diet, specific health conditions, or increased nutritional requirements, such as during pregnancy or rapid growth. If not detected and treated early, it can have a negative impact on overall health and daily functioning<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_Is_Folate_Important_for_the_Body\"><\/span><strong>Why Is Folate Important for the Body?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate is an essential vitamin that the body needs to function properly. It plays a key role in several important processes\u00a0such as:\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. Red Blood Cell Production<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-375x250.webp\" alt=\"blood cell\" class=\"wp-image-267762\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell-150x100.webp 150w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/blood-cell.webp 1536w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption class=\"wp-element-caption\"><sub>Image Source: freepik.com<\/sub><\/figcaption><\/figure><\/div>\n\n\n<p>Folate\u00a0helps the body produce healthy red blood cells in the bone marrow, which carry\u00a0oxygen\u00a0from the lungs to all parts of the body, helping organs and tissues function properly.\u00a0Inadequate\u00a0folate levels\u00a0lead to\u00a0abnormal red blood cell formation\u00a0and\u00a0cause\u00a0folate deficiency <a href=\"https:\/\/pharmeasy.in\/blog\/8-types-of-food-that-can-help-you-fight-anaemia\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>anaemia<\/strong><\/a>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. DNA\u00a0Synthesis\u00a0and Repair<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-375x250.webp\" alt=\"dna\" class=\"wp-image-269522\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2-150x100.webp 150w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/12\/dna-2.webp 1620w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption class=\"wp-element-caption\"><sub>Image Source: freepik.com<\/sub><\/figcaption><\/figure><\/div>\n\n\n<p>Folate is essential for\u00a0formation and\u00a0repairing\u00a0of\u00a0DNA,\u00a0the genetic material found in every cell of the body. It is especially important during periods of\u00a0rapid cell production and growth.\u00a0It works through\u00a0one-carbon metabolism,\u00a0a simple process\u00a0that helps the body build and repair DNA properly.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. Cell Growth and Division<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-375x250.webp\" alt=\"nerve cells\" class=\"wp-image-267390\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/05\/nerve-cells-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption class=\"wp-element-caption\"><sub>Image Source: freepik.com<\/sub><\/figcaption><\/figure><\/div>\n\n\n<p>\u00a0Folate plays a key role in\u00a0methylation reactions that help in gene regulation and amino acid production aiding\u00a0the formation of new cells. This is particularly important during pregnancy, childhood, adolescence, and recovery from illness or injury when the body is growing or healing quickly<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. Pregnancy and Foetal Development<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-375x250.webp\" alt=\"good for pregnancy\" class=\"wp-image-252274\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/good-for-pregnancy-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Folate is crucial during early pregnancy as it helps prevent neural tube defects (such as spina bifida) in the developing baby. Adequate intake before and during early pregnancy supports proper brain and spinal cord development\u00a0in baby<sup><a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5. Brain and Mental Health<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-375x250.webp\" alt=\"brain\" class=\"wp-image-208266\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-375x250.webp 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-1024x683.webp 1024w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-768x512.webp 768w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-1536x1024.webp 1536w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-2048x1365.webp 2048w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-741x494.webp 741w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-480x320.webp 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-720x480.webp 720w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27062955\/paper-brain-with-arrows-pointing-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Folate plays\u00a0an important role\u00a0in brain function as it helps\u00a0in making and managing chemicals that control mood, thinking, and memory. It also supports key body processes that keep brain cells healthy.\u00a0Studies show that low folate levels can cause\u00a0mood\u00a0changes\u00a0(depression), memory issues, and are at\u00a0higher risk of age-related mental decline<sup><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1123448\/\" target=\"_blank\" rel=\"noreferrer noopener\">4<\/a><\/sup>.<\/p><div id=\"sfa_container_277844\" class=\"sfa_container\" style=\"display:none\"><div class=\"sfa_overlay\"><\/div><button id=\"sfa_btn_277844\" class=\"sfa_btn\">Show Full Article<\/button><\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6. Heart Health\u00a0<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-375x250.webp\" alt=\"heart health\" class=\"wp-image-276472\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/04\/heart-with-cardiogram-light-background-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption class=\"wp-element-caption\"><sub>Image Source: freepik.com<\/sub><\/figcaption><\/figure><\/div>\n\n\n<p>Folate helps regulate homocysteine levels in the blood. High homocysteine is a risk factor for cardiovascular diseases, so adequate folate intake\u00a0can\u00a0support heart health<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27528407\/\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7. Overall\u00a0Health\u00a0Maintenance<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--375x250.webp\" alt=\"Boost Immunity\u00a0\" class=\"wp-image-276669\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/Boost-Immunity--150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption class=\"wp-element-caption\"><sub>Image Source: freepik.com<\/sub><\/figcaption><\/figure><\/div>\n\n\n<p>Folate\u00a0contributes to normal growth, development of tissues and organs, and overall good health, making it essential for people of all ages<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0Folate supplements should not be taken without proper medical guidance as they may mask signs of vitamin B12 deficiency with\u00a0nerve damage continuing\u00a0to progress.<\/em>\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Symptoms_of_Folate_Deficiency\"><\/span><strong>Symptoms of Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate deficiency can affect multiple systems in the body, leading to a range of symptoms involving the blood, brain, digestive system, and mouth.\u00a0The following are some common\u00a0folate deficiency symptoms.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. Folate Deficiency Anaemia\u00a0Symptoms<\/strong>\u00a0<\/h3>\n\n\n\n<ol><\/ol>\n\n\n\n<ul>\n<li><strong>Fatigue and weakness:\u00a0<\/strong>Feeling unusually tired or lacking energy due to reduced red blood cells.\u00a0<\/li>\n\n\n\n<li><strong>Pale skin:<\/strong>\u00a0Caused by decreased haemoglobin levels<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Jaundice\u00a0(if present):<\/strong>\u00a0Happens when poorly formed red blood cells break down early.\u00a0<\/li>\n\n\n\n<li><strong>Shortness of breath:<\/strong>\u00a0Especially during physical activity<sup><a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Fast\u00a0heartbeats\u00a0(palpitations):\u00a0<\/strong>As the heart works harder to supply oxygen<sup><a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. Neuropsychiatric\u202fSigns<\/strong>\u00a0<\/h3>\n\n\n\n<ul>\n<li><strong>Irritability or mood changes:\u00a0<\/strong>Feeling easily annoyed or emotionally unstable<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Difficulty concentrating:<\/strong>\u00a0Trouble focusing or thinking clearly<sup><a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Memory problems:<\/strong>\u00a0Difficulty with memory and thinking, especially in older adults<sup><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1123448\/\" target=\"_blank\" rel=\"noreferrer noopener\">4<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. Oral and Mucosal Problems<\/strong><\/h3>\n\n\n\n<ul>\n<li><strong>Mouth ulcers:\u00a0<\/strong>Painful sores inside the mouth<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Glossitis:<\/strong>\u00a0The tongue may appear\u00a0sore, red,\u00a0swollen\u00a0and smooth<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. Gastrointestinal Problems<\/strong><\/h3>\n\n\n\n<ul>\n<li><strong>Loss of appetite:<\/strong>\u00a0Reduced desire to eat.\u00a0<\/li>\n\n\n\n<li><strong>Weight loss:<\/strong>\u00a0Unintentional weight loss, often linked to poor appetite.\u00a0<\/li>\n\n\n\n<li><strong>Diarrhoea or digestive discomfort:<\/strong>\u00a0Due to effects on the intestinal lining<sup><a href=\"https:\/\/www.bda.uk.com\/resource\/folic-acid.html\" target=\"_blank\" rel=\"noreferrer noopener\">7<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Causes_of_Folate_Deficiency\"><\/span><strong>Causes of Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate deficiency can be\u00a0caused by a variety of reasons. The following are the most common\u00a0folate deficiency causes.\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Inadequate\u00a0Dietary\u00a0Intake:\u00a0<\/strong>Inadequate consumption of folate-rich foods such as green leafy vegetables, fruits, legumes, and fortified cereals can cause low folate levels in the body over time.\u00a0<\/li>\n\n\n\n<li><strong>Overcooking\u00a0Food:\u00a0<\/strong>Prolonged cooking, reheating, or boiling foods can\u00a0cause\u00a0significant\u00a0loss of\u00a0folate,\u00a0mainly because it leaches\u00a0(leaks)\u00a0into the cooking\u00a0water\u00a0and also\u00a0because it\u00a0is a heat-sensitive vitamin.\u00a0<\/li>\n\n\n\n<li><strong>Malabsorption\u00a0Disorders:\u00a0<\/strong>Conditions like Celiac disease and Crohn\u2019s disease damage the lining of the small intestine, reducing the body\u2019s ability to absorb folate properly.\u00a0<\/li>\n\n\n\n<li><strong>Excess Alcohol Consumption:\u00a0<\/strong>Alcohol interferes with folate absorption in the intestines, reduces its storage in the liver, and increases its excretion from the body.\u00a0<\/li>\n\n\n\n<li><strong>Certain\u00a0Medications<\/strong>:\u00a0Some drugs, such as <a href=\"https:\/\/pharmeasy.in\/molecules\/methotrexate-13\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>methotrexate<\/strong><\/a>, <a href=\"https:\/\/pharmeasy.in\/molecules\/phenytoin-58\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>phenytoin<\/strong><\/a>, <a href=\"https:\/\/pharmeasy.in\/molecules\/sulfasalazine-779\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>sulfasalazine<\/strong><\/a>, and <a href=\"https:\/\/pharmeasy.in\/molecules\/trimethoprim-2\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>trimethoprim<\/strong><\/a>\u00a0can interfere with folate absorption, metabolism, or utilisation in the body.\u00a0<\/li>\n\n\n\n<li><strong>Increased\u00a0Requirements:\u00a0<\/strong>Folate deficiency can develop when the body\u00a0requires\u00a0more folate than usual. This\u00a0can\u00a0occur during pregnancy, breastfeeding, and times of fast growth such as infancy, childhood, and adolescence. It can also occur in individuals undergoing haemodialysis (since folate is lost during the procedure; however,\u00a0significant deficiency is uncommon\u00a0with modern dialysis procedure)\u00a0and in some skin disorders such as dermatitis, where rapid cell division raises folate requirements.\u00a0<\/li>\n\n\n\n<li><strong>Genetic Factor:<\/strong>\u00a0A change in certain genes (such as MTHFR<strong>)<\/strong>\u00a0can make it harder for the body to use folate properly, even\u00a0if proper diet is followed.\u00a0<\/li>\n\n\n\n<li><strong>Vitamin B12 Deficiency:<\/strong>\u00a0Vitamin B12 deficiency causes\u00a0the\u00a0folate\u00a0to\u00a0get\u00a0trapped in a form that the body cannot use effectively<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Risk_Factors_for_Folate_Deficiency\"><\/span><strong>Risk Factors for Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Some people are more likely to develop folate deficiency than others.\u00a0People who are at a higher\u00a0risk\u00a0of developing folate deficiency includes the following:\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Pregnant Women:<\/strong>\u00a0During pregnancy, the body need more folate to support the baby\u2019s growth, particularly brain and spinal cord development. If this\u00a0additional\u00a0demand is not met,\u202fdeficiency can occur.\u00a0<\/li>\n\n\n\n<li><strong>People With Poor Diet:<\/strong>\u00a0Those who do not eat enough folate-rich foods like green leafy vegetables, fruits, beans, and fortified cereals may not get the required amount of folate\u00a0and are at risk.\u00a0<\/li>\n\n\n\n<li><strong>Alcohol Users:<\/strong>\u00a0People\u00a0who drink alcohol regularly or heavily may develop folate deficiency because alcohol interferes with the absorption and storage of folate in the body.\u00a0<\/li>\n\n\n\n<li><strong>People\u00a0With\u00a0Digestive\u00a0Problems:\u00a0<\/strong>People with conditions such as celiac disease may have a reduced ability to absorb folate properly from food.\u00a0<\/li>\n\n\n\n<li><strong>People\u00a0Taking\u00a0Certain\u00a0Medications:<\/strong>\u00a0People\u00a0who\u00a0consume certain medication\u00a0(methotrexate,\u00a0sulfasalazine,\u00a0trimethoprim, etc.)\u00a0are at risk as\u00a0these medicines interfere with how folate is absorbed or used in the body.\u00a0<\/li>\n\n\n\n<li><strong>Those\u00a0With\u00a0Increased\u00a0Needs:<\/strong>\u00a0Growing children, teenagers, and individuals recovering from illness or surgery may require more folate for tissue repair and growth, increasing their risk if intake is not sufficient<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Elderly:<\/strong>\u00a0Older adults may have poor dietary intake and reduced ability to absorb nutrients, making them more prone to folate deficiency<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25939915\/\" target=\"_blank\" rel=\"noreferrer noopener\">8<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0Many of these risk factors can also\u00a0predispose to\u00a0vitamin B12 deficiency, so B12 levels should be checked before treating with folate alone.<\/em>\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Folate_Deficiency_in_Pregnancy\"><\/span><strong>Folate Deficiency in Pregnancy<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate is extremely important during pregnancy as it supports the baby\u2019s quick growth and development. It is critical in the formation of the baby\u2019s brain, spinal cord, and other tissues, particularly in the first few weeks of pregnancy when many vital structures are growing.\u00a0<\/p>\n\n\n\n<p>One of folate\u2019s most significant functions is to help avoid neural tube defects, which are conditions that affect the development of the baby\u2019s brain and spine. Consuming adequate folate before and during early pregnancy promotes healthy development and lowers the chance of these issues.\u00a0<\/p>\n\n\n\n<p>Folate also helps the mother\u2019s body produce extra red blood cells needed during pregnancy and supports overall health and energy levels.\u00a0Because of these important roles,\u00a0pregnant women are usually advised to\u00a0ensure adequate folate intake through a healthy diet and\u00a0recommended\u00a0supplements<sup><a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<p>All women\u00a0planning for\u00a0pregnancy\u00a0are usually advised to take about\u00a0400 mcg of folic acid daily\u00a0to\u00a0maintain adequate folate levels in the body and\u00a0support\u00a0a healthy pregnancy<sup><a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.\u00a0Women at higher risk\u00a0(for example, those who had a previous baby with a birth defect or take certain medicines)\u00a0may need a higher dose (around 4-5 mg per day), but only if a doctor recommends it<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0Anaemia in pregnancy can have multiple causes, and iron deficiency is more common; therefore, both iron and folate levels should be\u00a0properly assessed\u00a0and managed.\u00a0Folate should not be taken on its own without checking for vitamin B12 deficiency, as it can hide blood problems while nerve damage may\u00a0still continue. All\u00a0supplementations\u00a0should be taken under the guidance of a doctor.\u00a0<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Complications_of_Folate_Deficiency\"><\/span><strong>Complications of Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate deficiency\u00a0can cause several complications, such as:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. Severe Blood Disorders\u00a0<\/strong><\/h3>\n\n\n\n<ol><\/ol>\n\n\n\n<ul>\n<li><strong>Megaloblastic Anaemia:\u00a0<\/strong>The main complication of the folate deficiency, where\u00a0the body produces huge, unhealthy red blood cells that\u00a0don\u2019t\u00a0function properly. As a result, less oxygen is delivered to various regions of the body, causing <a href=\"https:\/\/pharmeasy.in\/blog\/eat-these-10-foods-to-fight-fatigue\/\"><strong>fatigue<\/strong><\/a> and weakness<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537254\/\" target=\"_blank\" rel=\"noreferrer noopener\">9<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Pancytopenia:\u00a0<\/strong>In severe cases,\u00a0folate deficiency causes\u00a0decrease in all three types of blood cells,\u00a0red blood cells, white blood cells, and platelets.\u00a0This can affect immunity and cause several health problems<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a>,<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563146\/\" target=\"_blank\" rel=\"noreferrer noopener\">10<\/a><\/sup>.                                                                                                                                          <\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. Pregnancy and Developmental Complications<\/strong><\/h3>\n\n\n\n<ul>\n<li><strong>Neural Tube Defects (NTD):<\/strong>\u00a0Serious\u00a0birth defects that can affect a baby during early pregnancy. They include problems like spina bifida (when the spinal cord\u00a0doesn\u2019t\u00a0form properly) and anencephaly (when parts of the brain and skull\u00a0don\u2019t\u00a0develop properly)<sup><a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Pregnancy Loss &amp; Prematurity:<\/strong>\u00a0Increased\u00a0risk of miscarriage (loss of pregnancy-spontaneous abortion), and babies being born too early (preterm birth)<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. Brain and\u00a0Mental\u00a0Health\u00a0Problems<\/strong><\/h3>\n\n\n\n<ul>\n<li><strong>Cognitive decline<\/strong>:\u00a0Long-term folate deficiency can lead to memory problems, confusion, and a higher risk of conditions like dementia or Alzheimer\u2019s disease<sup><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1123448\/\" target=\"_blank\" rel=\"noreferrer noopener\">4<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Mental Health Issues<\/strong>:\u00a0Can cause depression, irritability and\u00a0difficulty falling asleep or staying asleep<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Neuropathy:\u00a0<\/strong>Although rare,\u00a0long-term severe folate deficiency can damage the nerves. This may cause symptoms like tingling, numbness, or weakness\u00a0in the body<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>. <\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. Other Health Problems<\/strong><\/h3>\n\n\n\n<ul>\n<li><strong>Heart Disease:\u00a0<\/strong>Increased\u00a0risk of heart-related problems as folate deficiency causes\u00a0a rise in a substance called homocysteine in the blood.\u00a0<\/li>\n\n\n\n<li><strong>Gastrointestinal Problems:<\/strong>\u00a0Long-lasting diarrhoea, unintentional weight loss, and swelling or soreness of the tongue (glossitis), along with mouth ulcers<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a>,<a href=\"https:\/\/www.bda.uk.com\/resource\/folic-acid.html\" target=\"_blank\" rel=\"noreferrer noopener\">7<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Fertility\u00a0Problems:<\/strong>\u00a0Difficulty in getting pregnant, which usually resolves by supplementation<sup><a href=\"https:\/\/www.nhs.uk\/conditions\/vitamin-b12-or-folate-deficiency-anaemia\/complications\/\" target=\"_blank\" rel=\"noreferrer noopener\">11<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diagnosis_of_Folate_Deficiency\"><\/span><strong>Diagnosis of Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>To\u00a0identify\u00a0folate deficiency,\u00a0your doctor might\u00a0evaluate a combination of symptoms, medical history, and laboratory test results rather than relying on a single sign.\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Clinical Evaluation:<\/strong>\u00a0Your doctor might\u00a0look\u00a0for\u00a0symptoms like tiredness, weakness, pale skin, mouth ulcers, or a sore tongue.\u00a0He might\u00a0also ask about your diet, alcohol\u00a0consumption, medication use, mood\u00a0changes\u00a0and any existing health problems<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Blood Tests:<\/strong>\u00a0Your doctor might\u00a0suggest <a href=\"https:\/\/pharmeasy.in\/diagnostics\/packages\/anaemia-care-health-checkup-1971\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>blood\u00a0tests for folate deficiency<\/strong><\/a>,\u00a0such as the following:\u00a0\n<ul>\n<li><strong><a href=\"https:\/\/pharmeasy.in\/diagnostics\/profile\/complete-blood-count-cbc-408\" target=\"_blank\" rel=\"noreferrer noopener\">Complete\u00a0Blood\u00a0Count (CBC)<\/a>:\u00a0<\/strong>Helps\u00a0the doctor to\u00a0identify\u00a0anaemia\u00a0and also\u00a0may show low haemoglobin levels and the presence of unusually large red blood cells (megaloblastic changes), due to\u00a0faulty DNA formation,\u00a0leading to ineffective red blood cell production.\u00a0<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/pharmeasy.in\/diagnostics\/tests\/folic-acid-1015\" target=\"_blank\" rel=\"noreferrer noopener\">Serum Folate Test<\/a>:<\/strong>\u00a0Measures\u00a0folate levels in the body, helping\u00a0the doctor\u00a0to confirm whether\u00a0folate\u00a0levels are low.\u00a0<\/li>\n\n\n\n<li><strong>Serum Homocysteine Levels<\/strong>:\u00a0Measures homocysteine levels to\u00a0identify\u00a0the deficiency.\u00a0<\/li>\n\n\n\n<li><strong>Peripheral Blood Smear<\/strong>:\u00a0Looks at your blood under a microscope, which\u00a0helps doctor\u00a0identify\u00a0whether there are\u00a0larger than normal red blood cells and\u00a0any\u00a0changes in white blood cells\u00a0which shows deficiency<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/pharmeasy.in\/diagnostics\/tests\/vitamin-b12-154\" target=\"_blank\" rel=\"noreferrer noopener\">Vitamin B12 Test<\/a>:<\/strong>\u00a0Your doctor might also suggest vitamin B12 test at the same time, because B12 deficiency can look\u00a0similar to\u00a0folate deficiency<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0\u00a0<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0Symptoms such as tingling, numbness, or nerve damage (neuropathy) are more commonly seen in vitamin B12 deficiency.\u00a0<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Treatment_of_Folate_Deficiency\"><\/span><strong>Treatment of Folate Deficiency<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>The treatment of folate deficiency\u00a0mainly focuses\u00a0on replacing the missing folate and treating the underlying cause.\u00a0You doctor might prescribe any of the following as a\u00a0folate deficiency treatment, based on your cause or condition.\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Folate supplements:\u00a0<\/strong>The most common treatment that might\u00a0doctor\u00a0prescribe.\u00a0Your doctor might give you\u00a0folic acid (vitamin B9) tablets\u00a0(usually a dose of 1-5 mg per day), which\u00a0help restore folate levels in the body.\u00a0<\/li>\n\n\n\n<li><strong>Improving Diet:<\/strong>\u00a0Your doctor might suggest a folate-rich diet\u00a0(leafy greens,\u00a0fruits, lentils, nuts, etc.)\u00a0along with other medications, which might help\u00a0maintain\u00a0folate levels in the long term.\u00a0<\/li>\n\n\n\n<li><strong>Treating Underlying Causes:<\/strong>\u00a0Your doctor\u00a0might\u00a0initiate\u00a0treatment for underlying causes like\u00a0digestive problems, alcohol use, or certain medications\u00a0such as:\u00a0\n<ul>\n<li>Treating gut disorders to improve absorption\u00a0<\/li>\n\n\n\n<li>Reducing alcohol intake\u00a0<\/li>\n\n\n\n<li>Adjusting medications if needed<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Special Care During Pregnancy:<\/strong>\u00a0If you are pregnant, your doctor might\u00a0give\u00a0you\u00a0folate\u00a0supplements to support the baby\u2019s development and\u00a0avoid\u00a0birth defects<sup><a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0Always check for vitamin B12 deficiency before starting folic acid, as folate may improve anaemia but can allow nerve damage to continue or worsen. This should only be done under your doctor\u2019s guidance.<\/em>\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_to_Manage_Folate_Deficiency_Naturally\"><\/span><strong>How to Manage Folate Deficiency Naturally?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"572\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-1024x572.webp\" alt=\"how to manage folate deficiency naturally\" class=\"wp-image-277889\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-1024x572.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-375x209.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-768x429.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-480x268.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-860x480.webp 860w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally-150x84.webp 150w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/How-to-Manage-Folate-Deficiency-Naturally.webp 1376w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<p>Folate deficiency can often be improved with simple lifestyle and diet changes. Here are some practical tips:\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Eat more folate-rich foods:<\/strong>\u00a0Include green leafy vegetables (like spinach), fruits (such as oranges and bananas), beans, lentils,\u00a0nuts, etc.\u00a0in your daily diet<sup><a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Choose\u00a0Fresh\u00a0Foods:<\/strong>\u00a0Avoid long storage or overcooking\u00a0which can cause folate\u00a0loss. Eating\u00a0fresh foods whenever possible\u00a0can\u00a0retain\u00a0the folate\u00a0content in food<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Include\u00a0Fortified\u00a0Foods:<\/strong>\u00a0Consume\u00a0cereals and grains\u00a0that\u00a0are fortified with folate.\u00a0This can give enough folate needed for your body<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Limit\u00a0Alcohol\u00a0Intake:<\/strong>\u00a0Reduce\u00a0alcohol\u00a0consumption.\u00a0This may\u00a0assist\u00a0your body take in and utilise folate more effectively<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Manage Medical Conditions:<\/strong>\u00a0Proper treatment of digestive or chronic illnesses, with the guidance of your doctor\u00a0can improve nutrient absorption<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong>\u00a0These tips\u202fcan help boost folate levels, but they are not a substitute for medical treatment. If you experience signs of folate deficiency or have been diagnosed with it, see a doctor for a complete diagnosis and treatment plan. In some circumstances, folic acid supplements or treatment may be\u00a0required.\u00a0Also,\u00a0ruling\u00a0out vitamin B12 deficiency before starting folate supplementation is important, as it may mask anaemia,\u00a0retaining\u00a0nerve damage.<\/em>\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"When_to_See_a_Doctor\"><\/span><strong>When to See a\u00a0Doctor?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Consider seeing a doctor if you have persistent tiredness or weakness even after rest, pale skin or shortness of breath, mouth ulcers or a sore tongue, memory problems or confusion, numbness or tingling in the hands and feet, unexplained weight loss, or long-lasting diarrhoea, which could indicate nutrient absorption problems.\u00a0<\/p>\n\n\n\n<p>It is especially important to seek medical guidance while pregnant or planning pregnancy, as folate is\u00a0required\u00a0for the baby\u2019s development. You should also <a href=\"https:\/\/pharmeasy.in\/online-doctor-consultation\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>see a doctor<\/strong><\/a> if you eat poorly, drink excessively, have digestive difficulties or chronic conditions that affect vitamin absorption, or are taking long-term drugs that may interfere with folate levels<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<p><strong><em>Also Read: <a href=\"https:\/\/pharmeasy.in\/blog\/7-things-you-need-to-avoid-in-anaemia\/\" target=\"_blank\" rel=\"noreferrer noopener\">7 Things You Need to Avoid in Anaemia!<\/a><\/em><\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span><strong>Conclusion<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Folate deficiency means\u00a0a condition that occurs when the body does not have enough folate to meet its needs. It is a common, yet\u00a0avoidable\u00a0condition that can negatively affect overall health if left untreated. Since folate is essential for blood formation, DNA synthesis,\u00a0repair\u00a0and\u00a0cell\u00a0growth,\u00a0maintaining\u00a0adequate levels through a balanced diet and healthy lifestyle is important.\u00a0It is especially important if you are pregnant or planning pregnancy.\u00a0Early detection\u00a0of any deficiency\u00a0and proper treatment can help\u00a0avoid\u00a0complications and support good health in people of all ages.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions_FAQs\"><\/span><strong>Frequently Asked Questions (FAQs)<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-question-1778164144859\"><strong class=\"schema-faq-question\"><strong>Can low folate be serious?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">Low folate can\u00a0sometimes be serious if left untreated, as it can lead to anaemia, fatigue, and other health problems.\u00a0In severe cases, it may cause complications like nerve issues or problems during pregnancy<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1778164176723\"><strong class=\"schema-faq-question\"><strong>How long does it take to recover from folate deficiency?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">Recovery from folate deficiency usually begins within a few days of starting folate\u00a0treatment, with blood levels improving over a few weeks.\u00a0Full recovery, including correction of anaemia and symptoms,\u00a0might\u00a0take about 4-8\u00a0weeks depending on severity and underlying cause<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1778164200601\"><strong class=\"schema-faq-question\"><strong>How can I raise my folate levels quickly?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">You can raise folate levels by eating folate-rich foods like leafy greens, fruits, beans, and fortified cereals.\u00a0Doctors may also recommend folic acid supplements for a quicker and more effective increase<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1778164224438\"><strong class=\"schema-faq-question\"><strong>What food is highest in folate?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">Leafy green vegetables like spinach,\u00a0mustard greens,\u00a0lettuce\u00a0etc.\u00a0are among the highest natural sources of folate.\u00a0Other rich foods include lentils, beans, oranges,\u00a0nuts\u00a0and fortified cereals<sup><a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1778164250460\"><strong class=\"schema-faq-question\"><strong>Is folate and B12 the same thing?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">No, folate (vitamin B9) and vitamin B12 are different vitamins.\u00a0Both help in red blood cell formation and DNA synthesis, but they have\u00a0different sources\u00a0and roles in the body<sup><a href=\"https:\/\/medlineplus.gov\/ency\/article\/002399.htm\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.<\/p> <\/div> <\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span><strong>References<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>1. Vitamins. 2025.\u00a0doi: <a href=\"https:\/\/medlineplus.gov\/ency\/article\/002399.htm\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/medlineplus.gov\/ency\/article\/002399.htm<\/a>\u00a0<\/p>\n\n\n\n<p>2. Baddam S, Khan KM,\u00a0Jialal\u00a0I. Folic Acid Deficiency. 2025.\u00a0doi: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535377\/<\/a>\u00a0<\/p>\n\n\n\n<p>3. About Folic Acid. 2025.\u00a0doi: <a href=\"https:\/\/www.cdc.gov\/folic-acid\/about\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.cdc.gov\/folic-acid\/about\/index.html<\/a>\u00a0<\/p>\n\n\n\n<p>4. Reynolds EH. Folic acid, ageing, depression, and dementia.\u00a0<em>BMJ<\/em>. 2002;324(7352):1512.1-1515. doi:10.1136\/bmj.324.7352.1512\u00a0<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1123448\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1123448\/<\/a><\/p>\n\n\n\n<p>5. Li Y, Huang T, Zheng Y, Muka T, Troup J, Hu FB. Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta\u2010Analysis of Randomized Controlled Trials.\u00a0<em>JAHA<\/em>. 2016;5(8):e003768. doi:10.1161\/JAHA.116.003768\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27528407\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27528407\/<\/a><\/p>\n\n\n\n<p>6. Folate Fact Sheet for Consumers. 2018.\u00a0doi: <a href=\"https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/ods.od.nih.gov\/pdf\/factsheets\/folate-consumer.pdf<\/a>\u00a0<\/p>\n\n\n\n<p>7. Folic Acid. 2023.\u00a0doi: <a href=\"https:\/\/www.bda.uk.com\/resource\/folic-acid.html\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.bda.uk.com\/resource\/folic-acid.html<\/a>\u00a0<\/p>\n\n\n\n<p>8. Ara\u00fajo JR, Martel F, Borges N, Ara\u00fajo JM, Keating E.\u00a0Folates\u00a0and aging: Role in mild cognitive impairment,\u00a0dementia\u00a0and depression.\u00a0<em>Ageing Research Reviews<\/em>.\u00a02015;22:9-19.\u00a0doi:10.1016\/j.arr.2015.04.005 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25939915\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25939915\/<\/a>\u00a0<\/p>\n\n\n\n<p>9. Hariz A, Bhattacharya PT. Megaloblastic\u00a0Anemia(Archived). 2023.\u00a0doi: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537254\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537254\/\u00a0<\/a><\/p>\n\n\n\n<p>10. Chiravuri S, Jesus OD. Pancytopenia. 2023.\u00a0doi: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563146\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563146\/<\/a>\u00a0<\/p>\n\n\n\n<p>11. Complications. 2023.\u00a0doi: <a href=\"https:\/\/www.nhs.uk\/conditions\/vitamin-b12-or-folate-deficiency-anaemia\/complications\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nhs.uk\/conditions\/vitamin-b12-or-folate-deficiency-anaemia\/complications\/<\/a>\u00a0<\/p>\n\n\n\n<p><em><strong>Disclaimer:<\/strong> The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n\n\n\n<p><em>Links and product recommendations in the information<\/em>\u00a0<em>provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products\/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes<\/em>.<\/p>\n<\/body><\/html>\n<div class=\"pld-like-dislike-wrap pld-custom\">\r\n    <div class=\"pld-like-wrap  pld-common-wrap\">\r\n    <a href=\"javascript:void(0)\" class=\"pld-like-trigger pld-like-dislike-trigger  \" title=\"Likes\" data-post-id=\"277844\" data-trigger-type=\"like\" data-restriction=\"cookie\" data-already-liked=\"0\">\r\n                            <img src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/12132143\/like.png\" alt=\"Likes\" \/>\r\n            <\/a>\r\n    <span class=\"pld-like-count-wrap pld-count-wrap\">    <\/span>\r\n<\/div><div class=\"pld-dislike-wrap  pld-common-wrap\">\r\n    <a href=\"javascript:void(0)\" class=\"pld-dislike-trigger pld-like-dislike-trigger  \" title=\"Dislikes\" data-post-id=\"277844\" data-trigger-type=\"dislike\" data-restriction=\"cookie\" data-already-liked=\"0\">\r\n                            <img src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/12132208\/dislike.png\" alt=\"Dislikes\" \/>\r\n            <\/a>\r\n    <span class=\"pld-dislike-count-wrap pld-count-wrap\"><\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Vitamins are essential substances that our body\u202fneeds to stay healthy and function properly. They play a key role in a variety of functions, including,\u00a0helping in\u00a0energy production, immunity, growth, and tissue repair. One such important vitamin is folate (vitamin B9).\u00a0Folate plays a key role in the formation of red blood cells and in the making [\u2026]","protected":false},"author":176,"featured_media":277878,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[1783,10435],"tags":[14292,14293,14296,14294,14297,14295],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/05\/Folate-Deficiency.webp"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/277844"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/176"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=277844"}],"version-history":[{"count":23,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/277844\/revisions"}],"predecessor-version":[{"id":277948,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/277844\/revisions\/277948"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/277878"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=277844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=277844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=277844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}