{"id":176653,"date":"2023-05-16T11:39:11","date_gmt":"2023-05-16T11:39:11","guid":{"rendered":"https:\/\/pharmeasy.in\/blog\/?p=176653"},"modified":"2026-03-11T10:18:58","modified_gmt":"2026-03-11T10:18:58","slug":"diagnostic-nephrotic-syndrome-causes-symptoms-treatment","status":"publish","type":"post","link":"https:\/\/pharmeasy.in\/blog\/diagnostic-nephrotic-syndrome-causes-symptoms-treatment\/","title":{"rendered":"Nephrotic Syndrome: Causes, Symptoms & Treatment"},"content":{"rendered":"\n\n<\/head>

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Table of Contents<\/p>\nToggle<\/span>

Introduction<\/a><\/li>
Signs and Symptoms of Nephrotic Syndrome<\/a><\/li>
Causes of Nephrotic Syndrome<\/a><\/li>
Risk Factors for Nephrotic Syndrome<\/a><\/li>
Diagnosis of Nephrotic Syndrome<\/a><\/li>
Treatment of Nephrotic Syndrome<\/a><\/li>
Prevention of Nephrotic Syndrome<\/a><\/li>
Complications of Nephrotic Syndrome<\/a><\/li>
When to See a Doctor?<\/a><\/li>
Frequently Asked Questions (FAQs)<\/a><\/li>
References<\/a><\/li><\/ul><\/nav><\/div>\n \n <\/span>\n $\"Join$ \n <\/a>\n
<\/span>Introduction<\/strong><\/span><\/h2>\n\n\n\nNephrotic syndrome is a medical condition that occurs when the kidney filters are damaged. These filters usually take back the protein in your blood and prevent it from going into the urine. When they are damaged, excess protein leaks into the urine. This can cause your body to lose important proteins that help maintain fluid balance in your blood vessels. As a result of this imbalance, some of the fluid starts to leak out into your tissues, leading to swelling, which is called oedema. You might notice swelling in your legs, ankles, or around your eyes. Your urine may also look foamy due to the extra protein in it 1<\/a><\/sup>.<\/p>\n\n\n\n
Let us discuss the causes, symptoms, and treatments available for nephrotic syndrome.<\/p>\n\n\n\n
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Did You Know?<\/strong><\/p>\n\n\n\n
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Focal Segmental Glomerulosclerosis (FSGS) is more likely to cause Nephrotic Syndrome in adults than in children, and it is most commonly found in individuals aged 45 years or older.<\/li>\n\n\n\n
In children, the primary cause of Nephrotic Syndrome is Minimal Change Disease, which is responsible for about 80% of cases 8<\/a><\/sup>.<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n
<\/span>Signs and Symptoms of Nephrotic Syndrome<\/strong><\/span><\/h2>\n\n\n\n
The following are the signs and symptoms of pneumonia, to look out for:<\/p>\n\n\n\n
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Excretion of high amounts of the protein albumin in the urine (albuminuria)<\/li>\n\n\n\n
Elevated levels of fat and cholesterol in the blood (hyperlipidemia)<\/li>\n\n\n\n
Swelling (oedema) usually in the feet, ankles, or legs that can also occur in the hands or face<\/li>\n\n\n\n
Reduced levels of albumin in the blood (hypoalbuminemia)<\/li>\n\n\n\n
Appetite loss<\/li>\n\n\n\n
Not feeling well<\/li>\n\n\n\n
Pain in the abdomen (from the ribs to the pelvis)<\/li>\n\n\n\n
Production of foamy urine 2<\/a><\/sup><\/li>\n<\/ul>\n\n\n\n
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Most children with nephrotic syndrome have times when their symptoms are under control (remission), followed by times when symptoms return (relapses). In most cases, relapses become less frequent as they get older and often stop by their late teens.<\/p>\n Dr. Ashish Bajaj, M.B.B.S, M.D.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n
<\/span>Causes of Nephrotic Syndrome<\/strong><\/span><\/h2>\n\n\n\n
Nephrotic syndrome can be caused by:<\/p>\n\n\n\n
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Nephrotic syndrome is typically caused by damage to the glomeruli, which are tiny blood vessels in the kidneys that filter the blood.<\/li>\n\n\n\n
Glomerular damage can result from various diseases and conditions, such as diabetic kidney disease, minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, systemic lupus erythematosus, and amyloidosis.<\/li>\n\n\n\n
Nephrotic syndrome can also be caused by secondary factors, including infections such as HIV\/AIDS, hepatitis B and C, certain medications such as non-steroidal anti-inflammatory drugs, some allergic reactions, genetic disorders that affect the kidneys, and other underlying medical conditions.<\/li>\n\n\n\n
The primary causes of nephrotic syndrome are focal segmental glomerulosclerosis (FSGS), membranous nephropathy, and minimal change disease.<\/li>\n\n\n\n
FSGS is the most common cause of nephrotic syndrome in Black adults, while membranous nephropathy is the most common cause in white adults, and minimal change disease is the main cause in children 4<\/a>,5<\/a><\/sup>.<\/li>\n<\/ul>
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