{"id":156932,"date":"2022-03-21T12:09:27","date_gmt":"2022-03-21T06:39:27","guid":{"rendered":"https:\/\/pharmeasy.in\/blog\/?p=156932"},"modified":"2026-03-02T10:56:29","modified_gmt":"2026-03-02T10:56:29","slug":"ayurveda-uses-benefits-side-effects-of-hadjod","status":"publish","type":"post","link":"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/","title":{"rendered":"Hadjod (Cissus Quadrangularis): Uses, Benefits, Side Effects &amp; More!"},"content":{"rendered":"<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><head><meta http-equiv=\"Content-Type\" content=\"text\/html; charset=utf-8\">\n<\/head><body><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69dfe6a29ef60\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"ez-toc-cssicon\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69dfe6a29ef60\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Introduction\" >Introduction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Nutritional_Value_of_Hadjod\" >Nutritional Value of Hadjod<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Uses_of_Hadjod\" >Uses of Hadjod<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Benefits_of_Hadjod\" >Benefits of Hadjod<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#How_to_Use_Hadjod\" >How to Use Hadjod?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Side_Effects_of_Hadjod\" >Side Effects of Hadjod<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#Frequently_Asked_Questions_FAQs\" >Frequently Asked Questions (FAQs)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-hadjod\/#References\" >References<\/a><\/li><\/ul><\/nav><\/div>\n    <a rel=\"nofollow\" href=\"https:\/\/pharmeasy.in\/blog\/channel-health-talk\"\n       class=\"pe-healthtalk-banner\"\n       style=\"position:relative; display:block; margin:10px; border-radius:10px; border-bottom:2px solid #117B77; overflow:hidden;\">\n        <span aria-hidden=\"true\" style=\"position:absolute; left:0; bottom:0; width:2px; height:50%; background:#10847e;\"><\/span>\n        <img alt=\"Join Health Talk by PharmEasy on WhatsApp\"\n             src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2026\/01\/PEhealthtalk-1.png\"\n             style=\"width:100%; display:block; border-radius:10px;\">\n    <\/a>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Introduction\"><\/span><strong>Introduction<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><em>Cissus quadrangularis<\/em>, commonly known as \u2018Hadjod\u2019 in Hindi, is a fleshy plant belonging to the <em>Vitaceae<\/em> family<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\">1<\/a><\/sup>. It is known by numerous vernacular names depending on the region. In Bangladesh, it is known as Hathisur in Sri Lanka, it is known as Heeressa in West Africa, it is known as Treebine, Zarnazaru, Banddiagra, Oongoonujaara in Thailand, it is known as Khankho, phet sangkhaat, san cha khuat and in India, it is known as Bonesetter, Adamant creeper, Veldt-grape, Hadjod, Hadsanka and Asthisamadhani. Hadjod, also known as Asthisamharaka, is a luscious herb found in India\u2019s warmest regions. It can grow up to 500 meters above sea level in plain coastal areas, forests, and wastelands.\u00a0Stem cuttings are used to propagate the herb.<strong> <\/strong>From June to December, the herb blooms. It is a climbing herb that turns leafless as it ages. It is a shrubby climber that can grow up to 1.5 meters tall. The plant blossoms small greenish-white flowers. The leaves are 2.5-5 cm long, broadly ovate or kidney-shaped leaves. The calyx is cup-shaped, short, and deciduous. There are 4-5 petals on each flower. The fruits are obovoid, very acrid, one-seeded, and dark purple to black. The stem is smooth, branched, glabrous, subangular, and fibrous and found to be buff colored with a greenish tinge. The stems measure 8\u201310 cm in length and 1\u20131.5 cm in width<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<strong>\u00a0<\/strong>Iridoids, alkaloids, flavonoids, stilbene derivatives, sterols, triterpenes, fatty acids, methyl esters, and other phytochemicals have been found in the hadjod. The presence of five well-known chemicals on leaves was discovered, including Tetratriacotanol, Ecosyl eicosanoate, Tetratriacontanoic acid, \u03b1,\u03b2-amyrin, \u03b2-sitosterol. Polyphenols such as Daidezein, Quercetin, and Genistein were also reported in the leaves<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\">1<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Nutritional_Value_of_Hadjod\"><\/span><strong>Nutritional Value of Hadjod<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>The nutritional content fount in hadjod root powder\/100 gm is:\u00a0<\/p>\n\n\n\n<ul>\n<li><strong>Carbohydrates<\/strong>: 68.89 \u00b1 1.16 mg<\/li>\n\n\n\n<li><strong>Proteins<\/strong>: 7.5 \u00b1 0.17 mg<\/li>\n\n\n\n<li><strong>Fibres<\/strong>: 5.97 \u00b1 0.10 mg<\/li>\n\n\n\n<li><strong>Potassium<\/strong>: 67.5 mg<\/li>\n\n\n\n<li><strong>Calcium<\/strong>: 39.5 mg<\/li>\n\n\n\n<li><strong>Zinc<\/strong>: 3 mg<\/li>\n\n\n\n<li><strong>Sodium<\/strong>: 22.5 mg<\/li>\n\n\n\n<li><strong>Iron<\/strong>: 7.5 mg<\/li>\n\n\n\n<li><strong>Lead<\/strong>: 3.5 mg<\/li>\n\n\n\n<li><strong>Cadmium<\/strong>: 39.5 mg<\/li>\n\n\n\n<li><strong>Copper<\/strong>: 0.5 mg<\/li>\n\n\n\n<li><strong>Magnesium<\/strong>: 1.15 mg<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Uses_of_Hadjod\"><\/span><strong>Uses of Hadjod<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul>\n<li><strong>Hadjod stems<\/strong>: It is used to treat various medical conditions. Furthermore, it is one of the most regularly utilized food supplements in southern India<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\">2<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod leaves:<\/strong> The plant\u2019s young shoots are considered stomachic<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod leaves powder:<\/strong> It is used to treat stomach problems<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod juice:<\/strong> For the union of fractured bones, it is given both internally and applied externally<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod shoot juice:<\/strong> When sprayed into the nostrils, the juice helps with epistaxis (nose bleeding). It is also used as an eardrop for otorrhea and irregular menstruation<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod shoot ash powder:<\/strong> The powder shoot ash is taken internally to treat dyspepsia<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n\n\n\n<li><strong>Hadjod root powder:<\/strong> It is used to union bone fractures and is also used to treat constipation and gout<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a><\/sup>.\u00a0<\/li>\n<\/ul><div id=\"sfa_container_156932\" class=\"sfa_container\" style=\"display:none\"><div class=\"sfa_overlay\"><\/div><button id=\"sfa_btn_156932\" class=\"sfa_btn\">Show Full Article<\/button><\/div>\n\n\n\n<blockquote class=\"wp-block-quote doc-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>Hadjod might be your ally in dental problems! Yes, you read it right Recent studies have revealed that the use of Hadjod may help in alleviating dental cavities when they start due to its anti-bacterial nature<sup><a href=\"https:\/\/saudijournals.com\/media\/articles\/SJODR_62_97-101_FT.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>.<\/p>\n<cite><strong><a href=\"https:\/\/pharmeasy.in\/legal\/editorial-policy\/dr-siddharth-gupta-73\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)<\/a><\/strong><\/cite><\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Benefits_of_Hadjod\"><\/span><strong>Benefits of Hadjod<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. Benefits of Hadjod for Pain<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-375x250.webp\" alt=\"osteoarthritis\" class=\"wp-image-208286\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-375x250.webp 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-1024x683.webp 1024w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-768x512.webp 768w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-1536x1024.webp 1536w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-2048x1365.webp 2048w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-741x494.webp 741w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-480x320.webp 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-720x480.webp 720w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27064531\/young-sport-woman-suffered-from-knee-pain-injury-while-running-city-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Traditional Hadjod folklore is that it is used to relieve pain. Animal models that are widely accepted worldwide were used to test its analgesic potential. Hadjod\u2019s effects were shown to be effective even at low doses, indicating that the herb has high potency in simulating central and peripheral pain. The phytosterols \u03b2-sitosterol and \u03b2-sitosterol glycoside, terpenoids, and phenolic substances such as resveratrol, quercetin, quercitrin, and kaempferol found in hadjod are thought to have analgesic properties<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. Benefits of Hadjod for Ulcer<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-375x250.webp\" alt=\"Gastric Ulcers\" class=\"wp-image-257467\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2023\/02\/Gastric-Ulcers-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>The presence of phytochemicals like polyphenols, glycosides, vitamin C, and \u03b2-sitosterol in hadjod may contribute to antiulcer potential or accelerate ulcer healing by releasing polyamines and transforming growth factor-\u00ce\u00b1. Hadjod displayed cytoprotection by increasing potassium, hexosamine, bicarbonate, and the carbohydrate, protein ratio while lowering pepsin, proteins, and acid secretion in the stomach<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. Benefits of Hadjod for Infections<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-375x250.webp\" alt=\"skin infections\" class=\"wp-image-255377\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/skin-infections-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Traditional literature mentions the use of hadjod in treating a variety of bacterial and viral infections. The steroids and flavonoids present in a partially purified extract of the hadjod stem were found to have excellent antiviral activity against herpes simplex virus types I and II<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>. In an antibacterial study, six different extracts of hadjod stem were tested against gram-positive and gram-negative bacteria. As a result, methanol extract was found to have superior antibacterial activity against <em>S. pyogenes<\/em>, <em>B. subtilis, S. aureus<\/em>, <em>P. aeruginosa,<\/em> and <em>S. typhi<\/em>, among other bacteria<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>. The antifungal activity of hadjod extract was determined by comparing it to the standard medication fluconazole. The diameter of the zone of inhibition generated on the surface of Petri dishes was used to determine antifungal activity. The study found that hadjod extract had promising antifungal efficacy against <em>Aspergillus flavus<\/em><sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\">1<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. Benefits of Hadjod for Worm Infections<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-375x250.webp\" alt=\"hadjod\" class=\"wp-image-258496\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>On the Haemonchus contortus worm, the anthelmintic activity of hadjod extract was investigated. The presence of alkaloids, flavonoids, tannins, and phenols in the extract may contribute to its anthelmintic effect<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5. Benefits of Hadjod for Cancer<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"227\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-375x227.webp\" alt=\"cancer\" class=\"wp-image-256387\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-375x227.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-1024x619.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-768x464.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-1536x928.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-2048x1237.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-480x290.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-794x480.webp 794w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/04\/cancer-150x91.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Hadjod has shown anticancer and antitumor activity in a variety of cancer cell lines, including breast cancer, osteosarcoma, leukaemia, Dalton\u2019s ascitic lymphoma, and Erlich ascitic-induced carcinoma. The extract of hadjod at various doses has been investigated to protect rats from breast cancer. All biochemical and haematological changes caused by 7,12-Dimethylben (a) anthracene were reversed when rats were given hadjod extract<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6. Benefits of Hadjod for Inflammation<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"252\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-375x252.webp\" alt=\"reduces inflammation\" class=\"wp-image-248383\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-375x252.webp 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-1024x688.webp 1024w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-768x516.webp 768w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-1536x1031.webp 1536w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-2048x1375.webp 2048w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-480x322.webp 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-715x480.webp 715w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/14060713\/reduces-inflammation-150x101.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Ear oedema was used to test hadjod\u2019s anti-inflammatory activity in rats. Hadjod can reduce swelling, relieve pain, treat allied illnesses associated with fractures, and aid in healing fractures. The inclusion of Beta-sitosterol and luteolin flavonoids in hadjod is responsible for its anti-inflammatory properties. Hadjod inhibits many inflammatory mediators that increase vascular permeability, support vasodilation, and cause oedema development<sup><a href=\"https:\/\/www.researchgate.net\/publication\/360411730_A_review_on_Cissus_quadrangularis_L_as_herbal_medicine\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7. Benefits of Hadjod for Obesity<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-375x250.webp\" alt=\"\" class=\"wp-image-257631\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/07\/Obesity-1-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>In hyperlipidemia models in rats, hadjod extract significantly reduced the total cholesterol, triglycerides, low-density lipoprotein cholesterol, and atherogenic index while increasing high-density lipoprotein cholesterol levels. Hadjod\u2019s antihyperlipidemic properties are thought to be related to phytosterols, including stigmasterol, \u03b2-sitosterol, ketosteroid, and flavonoids like kaemferol, quercetin, and daidzein. Phytosterols may lower low-density lipoprotein cholesterol levels or diminish intestinal cholesterol absorption by increasing faecal cholesterol excretion<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8. Benefits of Hadjod for Fertility<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"229\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/05100015\/Figs-for-Fertility-375x229.webp\" alt=\"fertility\" class=\"wp-image-214727\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/05100015\/Figs-for-Fertility-375x229.webp 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/05100015\/Figs-for-Fertility-480x293.webp 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/05100015\/Figs-for-Fertility-150x91.webp 150w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/05100015\/Figs-for-Fertility.webp 741w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>In rats, an extract of hadjod stem restored significant abnormalities caused by lead acetate. The use of hadjod extract on rats increases total sperm count. Antioxidant deficiency harms sperm viability and motility in males. Hadjod\u2019s anti-infertility effect is attributed to its antioxidant enzymes restorative capacity or pregnancy abruption, implantation inhibition, and abortion induction<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9. Benefits of Hadjod for Diabetes<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"223\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/12\/19144956\/Diabetes-375x223.jpg\" alt=\"fpg, ppg &amp; Hba1c numbers in diabetes\" class=\"wp-image-167279\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/12\/19144956\/Diabetes-375x223.jpg 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/12\/19144956\/Diabetes-480x285.jpg 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/12\/19144956\/Diabetes.jpg 760w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>In diabetic rats, the injection of hadjod extract at various doses considerably lowers blood glucose levels. Furthermore, hadjod extract caused a rise in plasma insulin levels and restored liver antioxidant enzymes and histology in diabetic mice. Improvements in glycemic metabolism and regulation, free radical elimination, cholesterol reduction, insulin secretion, and microcirculation can contribute to hadjod\u2019s antidiabetic action<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10. Benefits of Hadjod for Haemorrhoids<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-375x250.webp\" alt=\"Haemorrhoids\" class=\"wp-image-258497\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-1536x1025.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-2048x1366.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/Haemorrhoids-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Hadjod extract\u2019s anti-hemorrhoids activity was tested on an isolated human umbilical vein, which caused contraction of vascular smooth muscles of the vein. Hadjod extract was found to have a vasoconstrictive impact on the intact inner lining of the vein<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0In clinical research, taking a tablet of hadjod reduced piles symptoms in patients. Flavonoids, which are significant phytochemicals, are thought to help treat haemorrhoidal diseases by reducing localized bleeding, itching, and discomfort, potentially by improving capillary resistance and venous tonicity by lowering capillary permeability<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11. Benefits of Hadjod for Immunomodulation<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"300\" src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-375x300.webp\" alt=\"blood toxicity\" class=\"wp-image-208279\" style=\"width:335px;height:auto\" srcset=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-375x300.webp 375w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-1024x819.webp 1024w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-768x614.webp 768w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-1536x1229.webp 1536w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-2048x1638.webp 2048w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-480x384.webp 480w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-600x480.webp 600w, https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/06\/27063419\/red-blood-cells-150x120.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Hadjod\u2019s extract significantly increased blood carbon clearance, blood immunoglobulin levels, and a delayed type of hypersensitive response to sheep red blood cells. In another study, hadjod extract nanoparticles corrected immunosuppression in immunosuppressive animals using sheep red blood cells. The findings suggested that hadjod had immunomodulatory properties in both cellular and humoral immunity.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12. Benefits of Hadjod for Arthritis<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-375x250.webp\" alt=\"Arthritis\" class=\"wp-image-256492\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/01\/Arthritis-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Hadjod has been shown to have antiarthritic potential in various animal models. Hadjod extract was found to have an antiarthritic effect by reducing bone and cartilage degeneration, excessive paw inflammation, and associated biochemical and haematological changes<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13. Benefits of Hadjod for Bone Function<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-375x250.webp\" alt=\"\" class=\"wp-image-257925\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2025\/11\/bone-health-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Hadjod\u2019s antiosteoporotic potential has been demonstrated in various animal models by several authors. An osteoporotic rat model of ovariectomy, closed fracture by bending the radius-ulna in rats and dogs was used to test the antiarthritic activity of hadjod extract. The work was carried out <em>in vitro <\/em>using cell lines. Few clinical studies have shown that hadjod, combined with Zingiber officinale, can reduce joint swelling, discomfort, and soreness in osteoporotic and fractured patients. Hadjod\u2019s bone protective activity is thought to be due to its steroidal content, which functions as phytoestrogens to prevent or minimise bone loss and suppress bone reabsorption caused by oestrogen deficiency<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>14. Benefits of Hadjod as an Antioxidant Activity<\/strong><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"250\" src=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-375x250.webp\" alt=\"hadjod\" class=\"wp-image-258499\" srcset=\"https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-375x250.webp 375w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-1024x683.webp 1024w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-768x512.webp 768w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-1536x1024.webp 1536w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-2048x1365.webp 2048w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-741x494.webp 741w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-480x320.webp 480w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-720x480.webp 720w, https:\/\/pharmeasy.in\/blog\/wp-content\/uploads\/2022\/03\/hadjod-1-150x100.webp 150w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><\/figure><\/div>\n\n\n<p>Various research has already assessed the antioxidant activity of hadjod utilizing different antioxidant assays and procedures. By lowering serum enzyme levels and boosting antioxidant enzyme levels, the antioxidant activity of hadjod extract was examined on liver protective activity<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<blockquote class=\"wp-block-quote doc-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>I recently read an article that says Hadjod may be used as a diuretic. Hadjod is known for its anti-inflammatory and antioxidant properties<sup><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7649020\/\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><\/sup>.<\/p>\n<cite><strong><a href=\"https:\/\/pharmeasy.in\/legal\/editorial-policy\/dr-rajeev-singh-70\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Rajeev Singh, BAMS<\/a><\/strong><\/cite><\/blockquote>\n\n\n\n<p><strong><em>Also Read: <a href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-banana-leaf\/\" target=\"_blank\" rel=\"noreferrer noopener\">Banana Leaf: Uses, Benefits, Side Effects By Dr. Smita Barode<\/a><\/em><\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_to_Use_Hadjod\"><\/span><strong>How to Use Hadjod?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul>\n<li>Hadjod tablets<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>\u00a0<\/li>\n\n\n\n<li>Hadjod capsule<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup><\/li>\n\n\n\n<li>Hadjod powder<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup><\/li>\n\n\n\n<li>Hadjod drops<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup><\/li>\n<\/ul>\n\n\n\n<p>Your Ayurvedic physician will guide you for the appropriate dose and frequency of medication as per your condition. Avoid self-medication.\u00a0\u00a0<\/p>\n\n\n\n<p><em><strong>Also Read: <a href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-nutritional-value-of-kachnar\/\" target=\"_blank\" rel=\"noreferrer noopener\">Kachnar (Bauhinia Variegata): Uses, Benefits, Nutritional Value &amp; More!<\/a><\/strong><\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects_of_Hadjod\"><\/span><strong>Side Effects of Hadjod<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Various studies demonstrate that hadjod extracts are safe and free of side effects at commonly used doses. The reported side effects of hadjod extract are lack of appetite, staggering, dyspnoea, and diarrhoea in a limited case<sup><a href=\"https:\/\/escipub.com\/Articles\/AJCRR\/AJCRR-2020-07-1705.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">4<\/a><\/sup>.\u00a0<\/p>\n\n\n\n<p><strong><em>Also Read: <a href=\"https:\/\/pharmeasy.in\/blog\/ayurveda-uses-benefits-side-effects-of-akarkara\/\" target=\"_blank\" rel=\"noreferrer noopener\">Akarkara (Pellitory): Uses, Benefits, Side Effects &amp; More!<\/a><\/em><\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions_FAQs\"><\/span><strong>Frequently Asked Questions (FAQs)<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-question-1689333988324\"><strong class=\"schema-faq-question\"><strong>What are the synonyms of hadjod?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">It is known as Heeressa, Hathisur, Khankho, Zarnazaru, Treebine, Banddiagra, Oongoonujaara, phet sangkhaat, san cha khuat, Veldt-grape, Adamant creeper, Asthisamadhani, Bonesetter, and Hadsanka in different regions<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1689333998866\"><strong class=\"schema-faq-question\"><strong>What are the chemical constituents of hadjod?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">The plant contains several phytoconstituents like iridoids, stilbene derivatives, sterols, triterpenes, alkaloids, fatty acids, methyl esters, flavonoids<sup><a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a>,<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1689334042894\"><strong class=\"schema-faq-question\"><strong>What is the use of hadjod?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">It treats constipation, piles, tumours, blindness, loss of appetite, muscular pain, vata and kapha, epileptic fits, chronic ulcers, and bone fractures. It is also used as a digestive, anthelmintic, analgesic, laxative, stomachic, tonic aphrodisiac agent, treatment of back and spine problems, pus removal<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\">2<\/a><\/sup>.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1689334060380\"><strong class=\"schema-faq-question\"><strong>How to use hadjod?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">Hadjod is used in hadjod tablets, capsules, powder and drops<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\">2<\/a><\/sup>.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1689334068568\"><strong class=\"schema-faq-question\"><strong>Is a hadjod good for bone protection?<\/strong>\u00a0<\/strong> <p class=\"schema-faq-answer\">Yes, hadjod has bone protective activity. Hadjod\u2019s protective action is thought to be due to its steroidal content, which functions as phytoestrogens to prevent or minimise bone loss and suppress bone reabsorption caused by estrogen deficiency<sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\">2<\/a><\/sup>.<\/p> <\/div> <\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span><strong>References<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol>\n<li>Mukherjee T, Saha N, Palbag S. Ethnopharmacology, phytochemistry and pharmacology of ayurvedic plant hadjod-<em>Cissus quadrangularis<\/em> L. Int. J. Res. Ayurveda Pharm. 2016; 7(4): 78-83.\u00a0Available from: <a href=\"https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L\">https:\/\/www.researchgate.net\/publication\/305356131_ETHNOPHARMACOLOGY_PHYTOCHEMISTRY_AND_PHARMACOLOGY_OF_AYURVEDIC_PLANT_HADJOD_CISSUS_QUADRANGULARIS_L<\/a><\/li>\n\n\n\n<li>Bafna PS, Patil PH, Maru SK, Mutha RE. Cissus quadrangularis L: A comprehensive multidisciplinary review. Journal of Ethnopharmacology. 2021; 279: 114355.\u00a0Available from: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34181958\/<\/a><\/li>\n\n\n\n<li>Ravi L. A review on\u00a0<em>Cissus quadrangularis<\/em>\u00a0L. as herbal medicine. Ind J Natural Products Resources. 2020; 11(3): 155-164.\u00a0Available from: <a href=\"https:\/\/www.researchgate.net\/publication\/360411730_A_review_on_Cissus_quadrangularis_L_as_herbal_medicine\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.researchgate.net\/publication\/360411730_A_review_on_Cissus_quadrangularis_L_as_herbal_medicine<\/a><\/li>\n\n\n\n<li>A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, <em>Cissus quadrangularis<\/em> L. Am J Clin Res Rev; 2020; 4:18. Available from: <a href=\"https:\/\/escipub.com\/Articles\/AJCRR\/AJCRR-2020-07-1705.pdf\">https:\/\/escipub.com\/Articles\/AJCRR\/AJCRR-2020-07-1705.pdf<\/a><\/li>\n\n\n\n<li>Shingare P. Cissus Quadrangularis\u2013Potential Dental Biomaterial. Saudi J Oral Dent Res. 2021;6(2):97-101. doi:10.36348\/sjodr.2021.v06i02.003. Available from: <a href=\"https:\/\/saudijournals.com\/media\/articles\/SJODR_62_97-101_FT.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/saudijournals.com\/media\/articles\/SJODR_62_97-101_FT.pdf<\/a><\/li>\n\n\n\n<li>Sundaran J, Begum R, Vasanthi M, Kamalapathy M, Bupesh G, Sahoo U. A short review on pharmacological activity of Cissus quadrangularis. Bioinformation. 2020 Aug 31;16(8):579-585. doi: 10.6026\/97320630016579. PMID: 33214745; PMCID: PMC7649020. Available from: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7649020\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7649020\/<\/a><\/li>\n<\/ol>\n\n\n\n<p id=\"block-6cc7756d-7c4e-47a5-bd1e-ce62a0d9fa4f\"><strong><em>Disclaimer:<\/em><\/strong> <em>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n\n\n\n<p><em>Links and product recommendations in the information<\/em> <em>provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products\/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.<\/em><\/p>\n<\/body><\/html>\n<div class=\"pld-like-dislike-wrap pld-custom\">\r\n    <div class=\"pld-like-wrap  pld-common-wrap\">\r\n    <a href=\"javascript:void(0)\" class=\"pld-like-trigger pld-like-dislike-trigger  \" title=\"Likes\" data-post-id=\"156932\" data-trigger-type=\"like\" data-restriction=\"cookie\" data-already-liked=\"0\">\r\n                            <img src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/12132143\/like.png\" alt=\"Likes\" \/>\r\n            <\/a>\r\n    <span class=\"pld-like-count-wrap pld-count-wrap\">24    <\/span>\r\n<\/div><div class=\"pld-dislike-wrap  pld-common-wrap\">\r\n    <a href=\"javascript:void(0)\" class=\"pld-dislike-trigger pld-like-dislike-trigger  \" title=\"Dislikes\" data-post-id=\"156932\" data-trigger-type=\"dislike\" data-restriction=\"cookie\" data-already-liked=\"0\">\r\n                            <img src=\"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2024\/08\/12132208\/dislike.png\" alt=\"Dislikes\" \/>\r\n            <\/a>\r\n    <span class=\"pld-dislike-count-wrap pld-count-wrap\">1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Cissus quadrangularis, commonly known as \u2018Hadjod\u2019 in Hindi, is a fleshy plant belonging to the Vitaceae family1. It is known by numerous vernacular names depending on the region. In Bangladesh, it is known as Hathisur in Sri Lanka, it is known as Heeressa in West Africa, it is known as Treebine, Zarnazaru, Banddiagra, Oongoonujaara [\u2026]","protected":false},"author":93,"featured_media":157013,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[5405,219,5172,5173,1553,648],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/03\/21114115\/17Blog-Image-2.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/156932"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/93"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=156932"}],"version-history":[{"count":35,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/156932\/revisions"}],"predecessor-version":[{"id":259154,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/156932\/revisions\/259154"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/157013"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=156932"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=156932"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=156932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}