Table of Contents<\/p>\nToggle<\/span><\/path><\/svg><\/svg><\/span><\/span><\/label>Introduction<\/a><\/li>Properties of Kalmegh<\/a><\/li>Potential Uses of Kalmegh<\/a><\/li>How to Use Kalmegh?<\/a><\/li>Side Effects of Kalmegh<\/a><\/li>Precautions to Take With Kalmegh<\/a><\/li>Interactions With Other Drugs<\/a><\/li>Frequently Asked Questions (FAQs)<\/a><\/li>References<\/a><\/li><\/ul><\/nav><\/div>\n \n <\/span>\n \n <\/a>\n<\/span>Introduction<\/strong><\/span><\/h2>\n\n\n\nAndrographis paniculata<\/em> (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1<\/sup><\/a>.<\/p>\n\n\n\nKalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as a wonder drug in tribal medicine and in Indian Siddha, ayurvedic systems of medicine2<\/sup><\/a>,4<\/sup><\/a>.<\/p>\n\n\n\n<\/span>Properties of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nKalmegh is an important herb for its benefits for health, as it acts by inducing enzymes. Kalmegh\u2019s potential beneficial properties are as follows1<\/sup><\/a>:<\/p>\n\n\n\n\nIt may have immunity-building properties<\/li>\n\n\n\nIt may have antithrombotic properties that may help to reduce the risk of blood clots<\/li>\n\n\n\nIt may have the potential to help with typhoid<\/li>\n\n\n\nIt may have antimalarial properties<\/li>\n\n\n\nIt may have antibiotic properties<\/li>\n\n\n\nIt may have liver-protecting properties<\/li>\n\n\n\nIt may show anti-inflammatory activity.<\/li>\n<\/ul>\n\n\n\n<\/span>Potential Uses of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIndian systems of medicine, including Ayurveda, have been using the plant for its potential health benefits since ancient times. <\/sup>In countries like China, India, and other south-east Asian countries, kalmegh is traditionally used for various health conditions4<\/a><\/sup>.\u00a0 A variety of compounds that have been isolated from the plant may be used in medicinal formulations. The potential uses of kalmegh and its extracts are:<\/p>\n\n\n\n1. Potential Uses of Kalmegh in Infections<\/strong><\/h3>\n\n\n\nKalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Andrographis paniculata<\/em> (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1<\/sup><\/a>.<\/p>\n\n\n\nKalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as a wonder drug in tribal medicine and in Indian Siddha, ayurvedic systems of medicine2<\/sup><\/a>,4<\/sup><\/a>.<\/p>\n\n\n\n<\/span>Properties of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nKalmegh is an important herb for its benefits for health, as it acts by inducing enzymes. Kalmegh\u2019s potential beneficial properties are as follows1<\/sup><\/a>:<\/p>\n\n\n\n\nIt may have immunity-building properties<\/li>\n\n\n\nIt may have antithrombotic properties that may help to reduce the risk of blood clots<\/li>\n\n\n\nIt may have the potential to help with typhoid<\/li>\n\n\n\nIt may have antimalarial properties<\/li>\n\n\n\nIt may have antibiotic properties<\/li>\n\n\n\nIt may have liver-protecting properties<\/li>\n\n\n\nIt may show anti-inflammatory activity.<\/li>\n<\/ul>\n\n\n\n<\/span>Potential Uses of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIndian systems of medicine, including Ayurveda, have been using the plant for its potential health benefits since ancient times. <\/sup>In countries like China, India, and other south-east Asian countries, kalmegh is traditionally used for various health conditions4<\/a><\/sup>.\u00a0 A variety of compounds that have been isolated from the plant may be used in medicinal formulations. The potential uses of kalmegh and its extracts are:<\/p>\n\n\n\n1. Potential Uses of Kalmegh in Infections<\/strong><\/h3>\n\n\n\nKalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as a wonder drug in tribal medicine and in Indian Siddha, ayurvedic systems of medicine2<\/sup><\/a>,4<\/sup><\/a>.<\/p>\n\n\n\n<\/span>Properties of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nKalmegh is an important herb for its benefits for health, as it acts by inducing enzymes. Kalmegh\u2019s potential beneficial properties are as follows1<\/sup><\/a>:<\/p>\n\n\n\n\nIt may have immunity-building properties<\/li>\n\n\n\nIt may have antithrombotic properties that may help to reduce the risk of blood clots<\/li>\n\n\n\nIt may have the potential to help with typhoid<\/li>\n\n\n\nIt may have antimalarial properties<\/li>\n\n\n\nIt may have antibiotic properties<\/li>\n\n\n\nIt may have liver-protecting properties<\/li>\n\n\n\nIt may show anti-inflammatory activity.<\/li>\n<\/ul>\n\n\n\n<\/span>Potential Uses of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIndian systems of medicine, including Ayurveda, have been using the plant for its potential health benefits since ancient times. <\/sup>In countries like China, India, and other south-east Asian countries, kalmegh is traditionally used for various health conditions4<\/a><\/sup>.\u00a0 A variety of compounds that have been isolated from the plant may be used in medicinal formulations. The potential uses of kalmegh and its extracts are:<\/p>\n\n\n\n1. Potential Uses of Kalmegh in Infections<\/strong><\/h3>\n\n\n\nKalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh is an important herb for its benefits for health, as it acts by inducing enzymes. Kalmegh\u2019s potential beneficial properties are as follows1<\/sup><\/a>:<\/p>\n\n\n\n\nIt may have immunity-building properties<\/li>\n\n\n\nIt may have antithrombotic properties that may help to reduce the risk of blood clots<\/li>\n\n\n\nIt may have the potential to help with typhoid<\/li>\n\n\n\nIt may have antimalarial properties<\/li>\n\n\n\nIt may have antibiotic properties<\/li>\n\n\n\nIt may have liver-protecting properties<\/li>\n\n\n\nIt may show anti-inflammatory activity.<\/li>\n<\/ul>\n\n\n\n<\/span>Potential Uses of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIndian systems of medicine, including Ayurveda, have been using the plant for its potential health benefits since ancient times. <\/sup>In countries like China, India, and other south-east Asian countries, kalmegh is traditionally used for various health conditions4<\/a><\/sup>.\u00a0 A variety of compounds that have been isolated from the plant may be used in medicinal formulations. The potential uses of kalmegh and its extracts are:<\/p>\n\n\n\n1. Potential Uses of Kalmegh in Infections<\/strong><\/h3>\n\n\n\nKalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Indian systems of medicine, including Ayurveda, have been using the plant for its potential health benefits since ancient times. <\/sup>In countries like China, India, and other south-east Asian countries, kalmegh is traditionally used for various health conditions4<\/a><\/sup>.\u00a0 A variety of compounds that have been isolated from the plant may be used in medicinal formulations. The potential uses of kalmegh and its extracts are:<\/p>\n\n\n\n1. Potential Uses of Kalmegh in Infections<\/strong><\/h3>\n\n\n\nKalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh may not be a substitute for antibiotics, but it could have a complementary effect when used along with antibiotics for several infections. Some infections that may be helpful in are gastrointestinal tract infections, upper respiratory tract infections, throat infections, fever, and colds. It is, however, essential to consult your doctor before taking kalmegh for any infection3<\/sup><\/a>.<\/p>\n\n\n\n2. Potential Uses of Kalmegh as an Analgesic & Anti-inflammatory Herb<\/strong><\/h3>\n\n\n\nKalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh may act as a pain killer, and it may also reduce swelling and blood loss. The anti-inflammatory action of kalmagh may probably be mediated, in part, by its adrenal function. <\/sup>Moreover, for pain and inflammation2<\/sup><\/a>, consult your doctor for relief.<\/p>\n\n\n\n3. Potential Uses of Kalmegh in Improving Digestion<\/strong><\/h3>\n\n\n\nKalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh helps improve digestion due to its laxative properties; it aids in the elimination of faeces. It is also choleretic (helps in improving the properties of bile and causes a substantial increase in the flow of bile) and thus aids in digestion3<\/sup><\/a>.<\/p><\/div>Show Full Article<\/button><\/div>\n\n\n\n4. Potential Uses of Kalmegh for Protecting the Liver<\/strong><\/h3>\n\n\n\nKalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh may be effective against liver toxicity by producing a cleaning solvent and inhibiting the production of free radicals that destroy the cellular membranes that surround liver cells. Free radicals might cause liver cirrhosis. This can further result in coma and death. Studies5<\/sup><\/a> have shown that kalmegh may be an effective solution for infectious hepatitis. In a study5<\/sup><\/a>, decoction obtained from the kalmegh plant demonstrates cleaning and purifying activity, especially of blood. Thus, it may be used to cure jaundice. Kalmegh may be helpful for the treatment of fatty liver, and it can reduce the risk of gallstone formation. Thus, it might also aid in fat digestion2<\/sup><\/a>. <\/sup>Moreover, for any conditions related to the liver, you must be diagnosed and treated by a doctor.<\/p>\n\n\n\n5. Potential Uses of Kalmegh for Cancer Treatment<\/strong><\/h3>\n\n\n\nKalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh is believed to have a cancerolytic effect; it fights and may even kill cancer cells. Extract from kalmegh may have some effect on enhancing immune system functions. Studies6<\/sup><\/a> show the potential of kalmegh as it activates dual responses, making it effective against a variety of infectious and cancer-causing agents.\u00a0<\/p>\n\n\n\nDue to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n6. Potential Uses of Kalmegh in the Treatment of Ulcers<\/strong><\/h3>\n\n\n\nKalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Due to this ability, the National Cancer Institute terms kalmegh as a cytotoxic substance. It may also have lesser toxicity than most chemotherapeutic agents. While kalmegh shows potential in treatment for cancer, further research is needed to find which types of cancer respond to it.\u00a0\u00a0<\/p>\n\n\n\n
Kalmegh extract demonstrated antiulcerogenic activity. It may reduce the development of ulcers as it significantly decreases stomach acidity without any major side effects7<\/sup><\/a>. However, more studies are needed to establish its effect on ulcers in humans. Consult a doctor to get better advice.<\/p>\n\n\n\n7. Potential Uses of Kalmegh in the Treatment of Filaria<\/strong><\/h3>\n\n\n\nKalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh extracts may be effective in the treatment of filaria, in which there is obstruction of lymph channels leading to gross swelling termed elephantiasis8<\/sup><\/a>. It may show no apparent toxic effects. Though the exact effects of kalmegh on filaria are not known, thus you must consult a doctor.<\/p>\n\n\n\n8. Potential Uses of Kalmegh for the Treatment of Malaria<\/strong><\/h3>\n\n\n\nKalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kalmegh extract comprises of antimalarial substance, which is known to show activity against Plasmodium berghei (malaria-transmitting parasite). Its effects were found to be even better than that of an antimalarial drug9<\/sup><\/a>. It may control the spread of parasites which causes the spread of malaria, thus being more effective. <\/sup>Further studies can establish this effect of kalmegh.<\/p>\n\n\n\n9. Potential Uses of Kalmegh for Treatment of Inflammation<\/strong><\/h3>\n\n\n\nResearches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Researches10<\/sup><\/a> show the anti-inflammatory activity of kalmegh; it was found to inhibit oedema. <\/sup>It may also treat chronic inflammation of the colon in combination with prescription drugs. Local bacterial infection causes kidney inflammation. Studies11<\/sup><\/a> have shown kalmegh extracts to be effective in the treatment of this condition, and their performance was found to be comparable to the standard clinical drug used for the treatment. <\/sup>You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p>\n\n\n\n10. Potential Uses of kalmegh as Thrombolytic & Cardioprotective Substance<\/strong><\/h3>\n\n\n\nStudies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Studies12<\/sup><\/a> show that kalmegh has the potential to increase the time taken to clot clotting. It, may, therefore, reduce the risk of restenosis (closing of blood vessels) observed post-angioplasty. Contraction of blood vessels caused by injuries to the inner lining of blood vessels or by high cholesterol in the diet may also be reduced significantly by using kalmegh.<\/p>\n\n\n\nReduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Reduced blood supply and oxygen availability to heart muscles may cause the heart tissues to die. Kalmegh was found to stimulate the natural process in the body called fibrinolysis that dissolves blood clots in studies. <\/sup>However, such effects need to be proved by further research. Moreover, it is essential to consult a doctor before using kalmegh for any apparent health benefits.<\/p>\n\n\n\n11. Potential Uses of Kalmegh in Brain-related Disorders<\/strong><\/h3>\n\n\n\nKamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Kamegh may also help in maintaining the flow of blood and oxygen to the brain. It may therefore helpful in reducing the occurrence of memory loss, impaired mental performance, dizziness, headaches, depression, and ringing in the ears13<\/sup><\/a>. However, these effects need to be proved by further research and it is essential to consult a doctor before using kalmegh for any benefits.<\/p>\n\n\n\nThough there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Though there are studies that show the potential uses of kalmegh in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of kalmegh on human health.\u00a0\u00a0<\/p>\n\n\n\n
\nBased on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Based on some research14<\/sup><\/a>, I have found that andrographolide, present in Kalmegh, may have the potential in fighting HIV. Scientists created different versions of andrographolide and found that some derivatives were effective against HIV. Further research is needed, but these findings suggest that andrographolide derivatives might be useful in managing HIV.<\/p>\nDr. Smita Barode, B.A.M.S, M.S.<\/strong><\/a><\/cite><\/blockquote>\n\n\n\n<\/span>How to Use Kalmegh?<\/strong><\/span><\/h2>\n\n\n\nEvery part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n\nFresh leaves, dried leaves, and juice of the plant as an official drug.<\/li>\n\n\n\nTraditionally, garlic is added to kalmegh leaf powder with buttermilk for jaundice.<\/li>\n\n\n\nThe paste is formed by leaves and fresh twigs of the plant.<\/li>\n<\/ul>\n\n\n\nKindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\nAlso Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Every part of the kalmegh plant body may be used to obtain active pharmacological compounds for its benefit.<\/p>\n\n\n\n
Kindly refer to your doctor for advice, and consult a qualified doctor before taking any herbal supplements. Do not discontinue or replace an ongoing treatment of modern medicine with an ayurvedic\/herbal preparation without consulting a qualified doctor.<\/p>\n\n\n\n
Also Read: Bael (Aegle Marmelos): Uses, Benefits, Nutritional Value & Side Effects<\/a><\/strong><\/em><\/p>\n\n\n\n<\/span>Side Effects of Kalmegh<\/strong><\/span><\/h2>\n\n\n\nWhen consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n\nConsuming high amounts of kalmegh extract may lead to lethargy and decreased activity.<\/li>\n\n\n\nSome people may observe allergic reactions from kalmegh, varying from slight skin rashes to a potentially life-threatening allergic reaction called anaphylaxis due to high dosage.<\/li>\n\n\n\nKalmegh may have pregnancy-terminating effects and thus can abort the pregnancy.\u00a0<\/li>\n\n\n\nIt shows an antifertility effect as it prevents ovulation and reduces sperm count. Studies have also shown that it inhibits the production of progesterone.<\/li>\n<\/ul>\n\n\n\nIn case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
When consumed in moderation kalmegh may be safe, but overuse of kalmegh may produce some side effects such as.\u00a0\u00a0<\/p>\n\n\n\n
In case you experience such side effects you must consult your doctor<\/a><\/strong> for help they will prescribe a solution as per your condition.<\/p>\n\n\n\nAlso Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Also Read: Noni Fruit Juice: Uses, Benefits, Side Effects By Dr. Rajeev Singh<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Precautions to Take With Kalmegh<\/strong><\/span><\/h2>\n\n\n\nIt is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
It is advisable that, as a precaution, women may avoid kalmegh usage while they are pregnant. <\/sup>The safety of kalmegh in pregnant and breastfeeding women has not been fully studied. Likewise, no research has been done on the safety of kalmegh in children and elderly. Therefore, it should only be taken under the supervision and advice of a physician.<\/p>\n\n\n\nAlso Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Also Read: Chandraprabha Vati (Chandraprabha Gulika): Uses, Benefits, Side Effects, Precautions & More!<\/a><\/em><\/strong><\/p>\n\n\n\n<\/span>Interactions With Other Drugs<\/strong><\/span><\/h2>\n\n\n\nThere is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n<\/span>Frequently Asked Questions (FAQs)<\/strong><\/span><\/h2>\n\n\n\nIs kalmegh good for stomach ailments?\u00a0\u00a0<\/strong><\/strong> Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div> Can we use kalmegh as a sedative?\u00a0<\/strong><\/strong> It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div> Can kalmegh help diabetic patients?\u00a0<\/strong><\/strong> Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
There is not much information available on how kalmegh interacts with other medications. Hence, one should consult a doctor before taking barley if they take any other drug or supplement.<\/p>\n\n\n\n
Pills prepared by mixing juice obtained from the leaves of the kalmegh plant and spices (cardamom, clove, and cinnamon) are prescribed to relieve infants from stomach aches and other stomach ailments. You should consult a doctor for proper diagnosis and treatment for such conditions, it may be dangerous to self-medicate using herbs without proper information of its impact on your condition.<\/p> <\/div>
It is shown that kalmegh demonstrates some sedative effects. It is rather a relaxing herb as it is not as effective as established herbal sedatives, you should consult a doctor for advice on consuming kalmegh for its relaxing effect.<\/p> <\/div>
Kamegh decoction on oral use may reduce blood glucose levels as it demonstrates a hypoglycemic effect stimulating the release of insulin<\/a><\/strong> from the pancreas, which is similar to that of other antidiabetic medicines. <\/sup>However, conditions like diabetes must be diagnosed and treated by a doctor. Kindly consult a doctor and do not self-medicate.<\/p> <\/div> Can cholesterol levels in the body be reduced by using kalmegh?\u00a0<\/strong><\/strong> Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Studies14<\/sup><\/a> have shown extracts from kalmegh to have potential hypolipidemic effects. Moreover, it protects our heart without causing any damage to the liver. It reduces bad cholesterol (low-density lipoprotein) and triglyceride levels in the blood. Kindly consult a doctor as the diseases of the heart must be properly diagnosed and treated by a specialist.<\/p> <\/div> <\/div>\n\n\n\n<\/span>References<\/strong><\/span><\/h2>\n\n\n\n\nOkhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun;4(3):213\u2013222. doi:10.1016\/S2222-1808(14)60509-0. PMCID: PMC4032030. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4032030\/<\/a><\/li>\n\n\n\nMishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): a review. Pharmacogn Rev. 2007 Jul-Dec;1(2):283\u2013298. Available from: https:\/\/www.researchgate.net\/publication\/281535536_Andrographis_paniculata_Kalmegh_A_review<\/a><\/li>\n\n\n\nHossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Moh Qrimida A, Allzrag AMM, Ming LC, Pagano E, Capasso R. Andrographis paniculata (Burm. f.) Wall. ex Nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life (Basel). 2021 Apr 16;11(4):348. doi:10.3390\/life11040348. PMID: 33923529; PMCID: PMC8072717. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8072717\/<\/a><\/li>\n\n\n\nBhaisare S, Pathak S, Ajankar VV. Physiological activities of the King of Bitters (Andrographis paniculata<\/em>): a review. Cureus.<\/em> 2023 Aug 15;15(8):e43515. doi: 10.7759\/cureus.43515. PMID: 37719535; PMCID: PMC10501175. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10501175\/<\/a><\/li>\n\n\n\nChturvedi GN, Tomar GS, Tiwari SK, Singh KP. Clinical studies on kalmegh (Andrographis paniculata Nees) in infective hepatitis. Anc Sci Life. 1983 Apr\u2013Jun;2(4):208\u2013215. PMID: 22556984; PMCID: PMC3336768. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3336768\/<\/a><\/li>\n\n\n\nVarma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med. 2011;2011:815390. doi:10.1093\/ecam\/nep135. PMID: 19752167; PMCID: PMC3139959. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3139959\/<\/a><\/li>\n\n\n\nSaranya P, Geetha A, Selvamathy SM. A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer. Indian J Pharm Sci. 2011 Sep-Oct;73(5):550\u2013557. doi:10.4103\/0250-474X.99012. PMID: 22923868; PMCID: PMC3425067. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3425067\/<\/a><\/li>\n\n\n\nAl-Abd NM, Nor ZM, Al-Adhroey AH, Suhaimi A, Sivanandam S. Recent advances on the use of biochemical extracts as filaricidal agents. Evid Based Complement Alternat Med. 2013;2013:986573. doi:10.1155\/2013\/986573. PMID: 24298292; PMCID: PMC3835708. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3835708\/<\/a><\/li>\n\n\n\nMisra P, Pal NL, Guru PY, Katiyar JC, Srivastava V, Tandon JS. Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int J Pharmacogn. 1992;30(4):263\u2013274. doi:10.3109\/13880209209054010. Available from: https:\/\/www.researchgate.net\/publication\/232035136<\/a><\/li>\n\n\n\nManjula SD, Prasanna Kumar S, Rao VK. Anti-inflammatory activity of ten indigenous plants in carrageenan induced paw oedema in albino rats. Biomedicine (India). 2021;41(3):649\u2013653. doi:10.51248\/.v41i3.585. Available from: https:\/\/www.researchgate.net\/publication\/355775104<\/a><\/li>\n\n\n\nIntharuksa A, Arunotayanun W, Yooin W, Sirisa-ard P. A comprehensive review of Andrographis paniculata (Burm. f.) Nees and its constituents as potential lead compounds for COVID-19 drug discovery. Molecules. 2022 Jul 13;27(14):4479. doi:10.3390\/molecules27144479. PMID: 35889352; PMCID: PMC9316804. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9316804\/<\/a><\/li>\n\n\n\nWang DW, Zhao HY. Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata Nees and fish oil. Experimental studies of effects and mechanisms. Chin Med J (Engl). 1994 Jun;107(6):464\u201370. PMID: 7956489. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/7956489\/<\/a><\/li>\n\n\n\nSouza LC, Andrade MK, Azevedo EM, Ramos DC, Bail EL, Vital MABF. Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer\u2019s disease. Neurotox Res. 2022 Oct;40(5):1440\u20131454. doi:10.1007\/s12640-022-00569-5. Epub 2022 Aug 27. PMID: 36029454. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/36029454\/<\/a><\/li>\n\n\n\nJayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med. 2013;2013:846740. doi:10.1155\/2013\/846740. Epub 2013 Mar 24. PMID: 23634174; PMCID: PMC3619690. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3619690\/<\/a><\/li>\n<\/ol>\n\n\n\nDisclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Disclaimer:<\/strong>The information provided here is for educational\/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.<\/em><\/p>\n<\/body><\/html>\n\r\n \r\n \r\n \r\n <\/a>\r\n 39 <\/span>\r\n<\/div>\r\n \r\n \r\n <\/a>\r\n 1<\/span>\r\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Introduction Andrographis paniculata (Burm.f.) Nees is known as kalmegh in Hindi. It is known to be an important native crop of India and Srilanka1. Kalmegh is also called \u2018BhuiNeem\u2019 as it looks very similar to neem and, though smaller, has a bitter taste. Kalmegh is an erect herb that grows annually. It is used as [\u2026]","protected":false},"author":92,"featured_media":155853,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[6293],"tags":[],"acf":[],"_embedded":{"wp:featuredmedia":[{"source_url":"https:\/\/blog-images-1.pharmeasy.in\/blog\/production\/wp-content\/uploads\/2022\/02\/11131216\/kalmegh.jpg"}]},"_links":{"self":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849"}],"collection":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/users\/92"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/comments?post=155849"}],"version-history":[{"count":37,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions"}],"predecessor-version":[{"id":273831,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/posts\/155849\/revisions\/273831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media\/155853"}],"wp:attachment":[{"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/media?parent=155849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/categories?post=155849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmeasy.in\/blog\/wp-json\/wp\/v2\/tags?post=155849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}